The safety 100 patients on 700 mg will be important for other indication and in less degree to cancer , since cancer patients will be also on very toxic most of the time chemotherapy , they want to know how this mixture with Leronlimab will affect patients.
And they need to do that , this is basic...
This is why they starting with 350 mg dose , regardless what results we seeing with those 100 patients on 700 mg.