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Yes, lets start the trial. Here is the paper RP

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Post# of 154514
(Total Views: 216)
Posted On: 03/31/2019 7:36:44 PM
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Posted By: trding
Re: misiu143 #1523
Yes, lets start the trial.

Here is the paper RP’s slide is from for anyone that has not read it.

https://www.cell.com/cancer-cell/pdfExtended/...16)30087-3

Patient Summary

775578824_patientsmara.jpg

Result Summary

1329961026_patientsresults.jpg
1381832997_patientsresults1.jpg
993783430_patientsresults2.jpg
Quote:
Survival data from the MARACON trial is not conclusive due to the limited number of patients and the much more unfavorable clinical features of these patients compared with typical patient cohorts on fourth- or fifth-line therapy (Grothey et al., 2013). Looking at the trial data, it is nevertheless clear that the subsequent objective treatment responses are very encouraging. Historically the objective response rates in patients on or after the third line of chemotherapy are around 5%–10% (Nielsen et al., 2014).No large datasets exist on patients on or after fourth-line therapy, but objective responses were generally not observed and chemotherapy is only applied for symptom control (Arkenau et al., 2009). This is in contrast to our result of a high response rate in this advanced situation.





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