There are a few presentations showing leronlimab w

There are a few presentations showing leronlimab working on hiv resistant to mvc

Here is one
http://www.natap.org/2008/IAS/IAS_48.htm


The main poster I’m still searching for, the website has changed since, showing no emergence of viral resistance back in 2010 as referenced https://aidsinfo.nih.gov/drugs/423/leronlimab/0/professional.


Jacobson J, Morris S, Carpenito J, et al. Co-receptor tropism and viral resistance following short-term monotherapy with the anti-CCR5 monoclonal antibody PRO 140. Paper presented at: Conference on Retroviruses and Opportunistic Infections (CROI); February 16-19, 2010; San Francisco, CA. Paper 531. http://www.retroconference.org/2010/Abstracts/38126.htm


All these people working on it back then including MA Thompson, who Fine said was complaining about how long it is currently taking, apparently canned further developing pro 140, and didn’t for some reason try doses above 350mg, another complaint fine had of cydy, but it was really these guys that dropped the ball way back then. Luckily NP saw the potential or it probably would be still on a shelf with all the other ccr5 inhibitors.

https://www.ncbi.nlm.nih.gov/pubmed/20377413