Dolutegravir used a direct switch vs delayed switc
Post# of 148190
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Posted On: 03/01/2019 12:45:58 AM
Dolutegravir used a direct switch vs delayed switch in their comparison monotheorpy hiv trial.
I’m looking for a trial with an overlap with 5 half-lives though, with start-up vs maintenance phases. The 5 half-lives is the rule of thumb to reach steady state, but I’m still searching for reference with it in fda trials.
https://clinicaltrials.gov/ct2/show/NCT02401828
I’m looking for a trial with an overlap with 5 half-lives though, with start-up vs maintenance phases. The 5 half-lives is the rule of thumb to reach steady state, but I’m still searching for reference with it in fda trials.
https://clinicaltrials.gov/ct2/show/NCT02401828
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