Lets get cranking on our study! https://www.upi
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Posted On: 02/27/2019 3:58:58 PM
Lets get cranking on our study!
https://www.upi.com/Health_News/2019/02/26/On...551216963/
One dose of Keytruda may put melanoma into remission
"Researchers also investigated how tumor cells in patients whose cancer returned were able to develop a resistance to Keytruda. The investigators found two causes -- tumor mutations and increased activity of cells that naturally suppress the immune system.
Knowing the factors that cause a lack of response to the drug may help to identify patients who might benefit from other therapies in combination with PD-1, Wherry said.
Dr. Steven Savona, a physician at Northwell Health's Monter Cancer Center in Lake Success, N.Y., was not involved with the study, but reviewed the findings. He said the fast-acting immune response offers a new approach to a disease that used to be approachable only with surgery.
Savona said it could make the surgery simpler, and if used in combination with other treatments, surgery might not even be necessary for some patients.
"This might be a new approach for patients with limited but advanced melanoma, but we do need additional testing to prove that," said Savona.
Merck, Inc., maker of Keytruda, supplied the drug for the study but did not fund the trial."
https://www.upi.com/Health_News/2019/02/26/On...551216963/
One dose of Keytruda may put melanoma into remission
"Researchers also investigated how tumor cells in patients whose cancer returned were able to develop a resistance to Keytruda. The investigators found two causes -- tumor mutations and increased activity of cells that naturally suppress the immune system.
Knowing the factors that cause a lack of response to the drug may help to identify patients who might benefit from other therapies in combination with PD-1, Wherry said.
Dr. Steven Savona, a physician at Northwell Health's Monter Cancer Center in Lake Success, N.Y., was not involved with the study, but reviewed the findings. He said the fast-acting immune response offers a new approach to a disease that used to be approachable only with surgery.
Savona said it could make the surgery simpler, and if used in combination with other treatments, surgery might not even be necessary for some patients.
"This might be a new approach for patients with limited but advanced melanoma, but we do need additional testing to prove that," said Savona.
Merck, Inc., maker of Keytruda, supplied the drug for the study but did not fund the trial."
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