Smarty, My take on the sublingual tablet is tha
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Posted On: 02/25/2019 4:24:32 PM
Smarty,
My take on the sublingual tablet is that it's really a variety of products, at least one of which is intended for MM. I believe they would hope to have one formulation on the market sooner, which would be a substitute for smoking, and even that might offer a big variety of strengths and formulations. I'm certainly no expert on cannabis, but I know enough to know that all sorts of products exist, and I think they'd like to do the same with the sublingual tablet.
To the best of my knowledge, no form of cannabis that is smoked has ever been put through clinical testing, it's possible the sublingual tablet will only be tested to the point of showing it's a safe and effective replacement for smoking, but not to the point where it's approved as a drug. I believe the language from the company still supports such actions though I believe it's also clear that certain products are intended to go through the full drug approval process. The drug they use in the MM clinical trials may very much be like sublingual tablets on the market as a replacement for smoking.
I would suspect that once the sublingual tablet is available it may be found to be effective in cancer cachexia, the uncontrolled loss of weight people have while undergoing cancer treatment. Personally I believe hospital food is also largely responsible, at least some of the time, but I have little doubt that the sublingual tablet would have benefits for some patients who lose weight when even the finest foods don't tempt them to eat because of the side effects of the drugs they're taking.
Hospitals unfortunately still must prevent the use of cannabis for patients because they get Federal grants which could be lost if they're found to support the use of cannabis. I had been given some candy when undergoing treatment years ago and the nurses went ballistic when they learned about it, even though it was something that could be legally purchased in California. I think most Doctors, and even the nurses recognize it has benefits, but the fear of losing Federal funding prevents them from advocating its use. Hopefully this will change at some point in the not to distant future. My Dr. at City of Hope is at least interested in the trials being initiated that use a cannabis product for GVHD. I suspect that if the trial is FDA approved it can be done in the U.S. without repercussions from the Federal Govt. I'm approaching 4 years post stem cell transplant, so I don't need the drug, but I do hope it works for others and while the initial testing is being done with leukemia, it may be found to have benefits in other types of transplantation.
Gary
My take on the sublingual tablet is that it's really a variety of products, at least one of which is intended for MM. I believe they would hope to have one formulation on the market sooner, which would be a substitute for smoking, and even that might offer a big variety of strengths and formulations. I'm certainly no expert on cannabis, but I know enough to know that all sorts of products exist, and I think they'd like to do the same with the sublingual tablet.
To the best of my knowledge, no form of cannabis that is smoked has ever been put through clinical testing, it's possible the sublingual tablet will only be tested to the point of showing it's a safe and effective replacement for smoking, but not to the point where it's approved as a drug. I believe the language from the company still supports such actions though I believe it's also clear that certain products are intended to go through the full drug approval process. The drug they use in the MM clinical trials may very much be like sublingual tablets on the market as a replacement for smoking.
I would suspect that once the sublingual tablet is available it may be found to be effective in cancer cachexia, the uncontrolled loss of weight people have while undergoing cancer treatment. Personally I believe hospital food is also largely responsible, at least some of the time, but I have little doubt that the sublingual tablet would have benefits for some patients who lose weight when even the finest foods don't tempt them to eat because of the side effects of the drugs they're taking.
Hospitals unfortunately still must prevent the use of cannabis for patients because they get Federal grants which could be lost if they're found to support the use of cannabis. I had been given some candy when undergoing treatment years ago and the nurses went ballistic when they learned about it, even though it was something that could be legally purchased in California. I think most Doctors, and even the nurses recognize it has benefits, but the fear of losing Federal funding prevents them from advocating its use. Hopefully this will change at some point in the not to distant future. My Dr. at City of Hope is at least interested in the trials being initiated that use a cannabis product for GVHD. I suspect that if the trial is FDA approved it can be done in the U.S. without repercussions from the Federal Govt. I'm approaching 4 years post stem cell transplant, so I don't need the drug, but I do hope it works for others and while the initial testing is being done with leukemia, it may be found to have benefits in other types of transplantation.
Gary
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