Dublin, Feb. 14, 2019 (GLOBE NEWSWIRE) -- The "Prader-Willi Syndrome - Market Insights, Epidemiology and Market Forecast-2028" report has been added to ResearchAndMarkets.com's offering. The global market of Prader-Willi Syndrome (PWS) was estimated to be USD 2110.17 million in 2018 Prader-Willi Syndrome - Market Insights, Epidemiology and Market Forecast-2028' report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Prader-Willi Syndrome in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan. The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Prader-Willi Syndrome (PWS) from 2017 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market. Prader-Willi Syndrome Epidemiology According to this research, the prevalent population of Prader-Willi Syndrome was estimated to be 47,560 [7MM] in 2018. United States accounts for the highest Prader-Willi cases, followed by EU5 (Germany, France, Italy, Spain & UK) and Japan. Among the EU5 countries Germany had the highest prevalent patient population of Prader-Willi Syndrome, followed by Italy. Prader-Willi Syndrome Drug Chapters At present, pharmacological management of Prader-Willi Syndrome focuses largely on the use of human growth hormone (HGH) supplementation which is approved in the US. Growth hormone supplementation constitutes the primary component of the entire therapeutic market composition due to the nearly ubiquitous deficiency of growth hormone (GH) in PWS patients. Some of the majorly approved GH therapies include Pfizer's Genotropin (somatropin) along with other major brands such as Norditropin (Novo Nordisk) and a few others in the US. Central nervous system and cardiovascular agents are used with increasing frequency in older PWS patients. Another approved drug is Omnitrope (somatropin [rDNA origin] injection) from Sandoz. Detailed chapters for all of these drug therapies have been covered in the report. Prader-Willi Syndrome Market Outlook Amongst the therapeutic class, Hormone Therapies hold the highest patient share [%] amongst the other therapeutic options available for the treatment of PWS. The increasing awareness of the disease assisted by organizational support along with the promising pipeline therapies is expected to fuel the market size during the forecasted period of 2019-2028. Prader-Willi Syndrome Drugs Uptake This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2017-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug. This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions. Upcoming therapies, such as DCCR (Soleno Therapeutics), LV-101 (Levo Therapeutics) and Lariglutide (Novo Nordisk), have the potential to create a positive shift in the PWS market size during the study period (2017-2028). Expected launch of potential therapies will lead to an increase in the market size of Prader-Willi Syndrome (PWS) in the coming years. DCCR (Soleno Therapeutics) is the going to be the first FDA approved therapy that is expected to be launched in all of the 7 Major Markets, during the forecast period [2018-2028]. Key Topics Covered: 1 Key Insights 2 Prader-Willi Syndrome Market Overview at a Glance 2.1 Market Share (%) Distribution of Prader-Willi Syndrome in 2017 2.2 Market Share (%) Distribution of Prader-Willi Syndrome in 2028 3 Prader-Willi syndrome: Disease Background and Overview 3.1 Introduction 3.2 Cause 3.3 Symptoms 3.4 Complications 3.5 Stages of Prader-Willi Syndrome 3.6 Molecular Genetic Pathogenesis 3.7 Diagnosis 4 Epidemiology and Patient Population 4.1 Key Findings 4.2 Population and Forecast Parameters 4.3 Total Prevalence of Prader-Willi Syndrome in 7MM 5 Country Wise-Epidemiology of Prader-Willi Syndrome 6 United States 6.1 Assumptions and Rationale 6.2 Prevalent Population of Prader-Willi Syndrome (PWS) in the United States 6.3 Diagnosed cases of PWS in the US 6.4 PWS cases by Mutation Types in the US 6.5 PWS associated Clinical Manifestations 7 EU-5 7.1 Assumptions and Rationale 8 Germany 8.1 Prevalent Population of Prader-Willi Syndrome (PWS) in Germany 8.2 Diagnosed cases of PWS in Germany 8.3 PWS cases by Mutation Types in Germany 8.4 PWS associated Clinical Manifestations 9 France 10 Italy 11 Spain 12 United Kingdom 13 Japan 14 Treatment 14.1.1 Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome 15 Unmet Needs 16 Marketed Drugs 16.1 GENOTROPIN: Pfizer 16.2 Other Hormonal Therapies 16.2.1 OMNITROPE: Sandoz Inc 16.3 Norditropin: Novo Nordisk 17 Emerging Drugs Analysis 18 Emerging Therapies 18.1 Diazoxide Choline Controlled-Release: Soleno Therapeutics 18.2 LV-101: Levo Therapeutics 18.3 Liraglutide: Novo Nordisk 18.3 Livoletide: Millendo Therapeutics 19 Prader-Willi Syndrome: 7 Major Market Analysis 19.1 Key Findings 19.2 Total Market Size of Prader-Willi Syndrome in 7MM 19.3 7 MM Size of Prader-Willi Syndrome by Therapies 20 Market Outlook by Country 20.1 The United States: Market Outlook 20.2 United States Market Size 20.3 EU-5 Countries: Market Outlook 20.4 Germany Market Size 20.5 France Market Size 20.6 Italy Market Size 20.7 Spain Market Size 20.8 The United Kingdom Market Size 20.9 Japan: Market Outlook 21 Market Drivers 22 Market Barriers 23 Appendix Companies Mentioned
- Pfizer
- Sandoz Inc
- Novo Nordisk
- Soleno Therapeutics
- Levo Therapeutics
- Millendo Therapeutics
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