Innovation Pharmaceuticals Expands Brilacidin Pate
Post# of 72436
BEVERLY, Mass., Nov. 01, 2018 (GLOBE NEWSWIRE) -- Innovation Pharmaceuticals, (IPIX) (“the Company”), a clinical stage biopharmaceutical company, is pleased to report that the U.S. Patent & Trademark Office recently announced the allowance of another application directed to Brilacidin.
The “Notice of Allowance” is directed to Brilacidin oral, buccal, and sublingual pharmaceutical compositions. The allowed claims for Brilacidin pharmaceutical compositions include liquid compositions, such as rinses. Previously issued U.S. Patents for Brilacidin include U.S. Patent Numbers: 8,802,683; 9,155,738; 9,457,027; and 9,795,575.
“These new patent protections further bolster the intellectual property estate that we’ve built around Brilacidin, our novel Host Defense Protein mimetic drug candidate,” commented Arthur P. Bertolino, MD, PhD, MBA, President and Chief Medical Officer at Innovation Pharmaceuticals. “The new allowances are of particular relevance to Brilacidin for the treatment of oral mucositis, in head and neck cancer patients, administered as a convenient oral rinse. The Company currently is preparing for an End-of-Phase 2 meeting with the FDA to discuss Brilacidin oral rinse continued development in addressing this area of large unmet need. Future clinical applications of Brilacidin in liquid form to treat other indications may potentially include chronic sinusitis and infections related to periodontal disease.”
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About Innovation Pharmaceuticals
Innovation Pharmaceuticals Inc. (IPIX) is a clinical stage biopharmaceutical company developing a world-class portfolio of innovative therapies addressing multiple areas of unmet medical need, including inflammatory diseases, cancer, infectious disease, and dermatologic diseases. Brilacidin, a versatile compound with broad therapeutic potential, is in a new chemical class called defensin-mimetics. A Phase 2 trial of Brilacidin as an oral rinse for the prevention of Severe Oral Mucositis (SOM) in patients with Head and Neck Cancer, met its primary and secondary endpoints, including reducing the incidence of SOM. Positive results were also observed in a Phase 2 Proof-of-Concept trial treating patients locally with Brilacidin for Ulcerative Proctitis/Ulcerative Proctosigmoiditis. A Phase 2b trial of Brilacidin showed a single intravenous dose of the drug delivered comparable outcomes to a seven-day dosing regimen of the FDA-approved blockbuster daptomycin in treating Acute Bacterial Skin and Skin Structure Infections. Kevetrin is a novel anti-cancer drug shown to modulate p53, often referred to as the “Guardian Angel Gene” due to its crucial role in controlling cell mutations, and has successfully completed a Phase 2 trial in ovarian cancer. Prurisol, an oral psoriasis drug candidate acting through immune modulation and PRINS reduction, has now completed a Phase 2b trial and is awaiting statistical analysis. More information is available on the Company website at www.IPharmInc.com.
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