Pratteln, Switzerland, August 21, 2018 - Santhera Pharmaceuticals (SIX: SANN) will announce its first half-year financial figures for 2018 and provide a corporate update on Tuesday, September 4, 2018, at 07:00 CEST / 06:00 BST / 01:00 EDT. A conference call with Thomas Meier, PhD, CEO of Santhera and Christoph Rentsch, CFO of Santhera, will be held in English on the same day at 13:00 CEST / 12:00 BST / 07:00 EDT. Participants are invited to dial one of the following numbers 10-15 minutes before the conference call starts (no dial-in code is required): Europe:    +41 58 310 50 00 UK:            +44 207 107 0613 USA:          +1 631 570 5613 Half-year Report 2018 and press release will be available on www.santhera.com from 07:00 CEST. About Santhera Santhera Pharmaceuticals (SIX: SANN) is a Swiss specialty pharmaceutical company focused on the development and commercialization of innovative medicines for rare and other diseases with high unmet medical needs. The portfolio comprises clinical stage and marketed treatments for neuro-ophthalmologic, neuromuscular and pulmonary diseases. Santhera's Raxone® (idebenone) is authorized in the European Union, Norway, Iceland, Liechtenstein and Israel for the treatment of Leber's hereditary optic neuropathy (LHON) and is currently commercialized in more than 20 countries. For further information, please visit www.santhera.com . Raxone ® is a trademark of Santhera Pharmaceuticals. For further information please contact: public-relations@santhera.com or Eva Kalias, Head External Communications Phone: +41 79 875 27 80 eva.kalias@santhera.com For Investors: investor-relations@santhera.com or Christoph Rentsch, Chief Financial Officer                                  Hans Vitzthum, LifeSci Advisors Europe: +41 61 906 89 65                                                                US: +1 212 915 2568 christoph.rentsch@santhera.com                                                hans@lifesciadvisors.com Disclaimer / Forward-looking statements This communication does not constitute an offer or invitation to subscribe for or purchase any securities of Santhera Pharmaceuticals Holding AG. This publication may contain certain forward-looking statements concerning the Company and its business. Such statements involve certain risks, uncertainties and other factors which could cause the actual results, financial condition, performance or achievements of the Company to be materially different from those expressed or implied by such statements. Readers should therefore not place undue reliance on these statements, particularly not in connection with any contract or investment decision. The Company disclaims any obligation to update these forward-looking statements. # # #

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