In reply to Kswiss12 question What is Amniostem?
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Posted On: 06/27/2018 9:00:32 PM
In reply to Kswiss12 question What is Amniostem?
In layman's terms Amniostem is the secret ingredient in KFC chicken + Coca Cola + In and Out Burger's sauce + +. These things aren't really secret just like amniotic fluid has been around since Adam and Eve. Use of that fluid to get usable injectable stem cells is secret. The patened technology is practical isolation and growth of the cells that can be tailored for specific commercial applications.
This is perhaps why this stock has gone up 500% since February, but that is only opinion.
The due dilligence portion of IHANG website has better graphics and is easier to read
WHAT IS AMNIOSTEM?
Amniotic fluid derived stem cell
Issued US patent, licensed from UCSD
Covering composition of matter and practical isolation procedures for amniotic fluid stem cells
“AmnioStem Patent Covers Means to Isolate, Grow and Use Amniotic Fluid Derived Stem Cells in a Scalable and Commercializable Manner”
WHY IS AMNIOTIC FLUID SPECIAL?
Clear, yellowish liquid, surrounds fetus during pregnancy
Continuously inhaled, exhaled by fetus
98% water, proteins, peptides, carbohydrates, lipids and hormones
Protects the developing fetus, promotes growth
AMNIOTIC FLUID STEM CELLS
2001: Atala group postulates existence of c-kit positive stem cells, no means of practical expansion
2003: Prusa et al described stem cell markers in amniotic fluid, no means of expansion
2003: Martin Haas at UCSD (our inventor) Practical protocol for isolation, expansion and growth of amniotic fluid stem cells
2007: First publication on practical use of amniotic stem cells (DeCoppi et al)
“Since 2007 there have been over 600 peer-reviewed publications on the benefits of amniotic fluid stem cells”
AMNIOSTEM IS PRACTICAL STEM CELL THERAPY
Practical protocol for generating therapeutic quality stem cells starting from small (1-5 ml) amniocentesis sample
Do not mutate and maintain phenotype
Large scale expansion of stem cells feasible, with 1 donor generating >20,000 doses
AmnioStem cells do not require matching with recipient (one size fits all)
LOCATION ON THE STEM CELL CONTINUUM
GENERATION OF THERAPEUTIC AMNIOTIC FLUID DERIVED STEM CELLS
ADVANTAGES
Embryonic
Stem Cells Amniotic Fluid Stem Cells Adult
Stem Cells
Developmental potential Pluripotent Pluripotent or multipotent Multipotent
Renewal capacity Very high expansion in cell culture High expansion Limited
Potential for tumor formation Yes No No
Ethical considerations Serious ethical issues raised using embryos No issues; obtained during routine procedures No
What is Amniostem?
Treating Stroke
Pre-Clinical Research
Clinical Research Plan
In layman's terms Amniostem is the secret ingredient in KFC chicken + Coca Cola + In and Out Burger's sauce + +. These things aren't really secret just like amniotic fluid has been around since Adam and Eve. Use of that fluid to get usable injectable stem cells is secret. The patened technology is practical isolation and growth of the cells that can be tailored for specific commercial applications.
This is perhaps why this stock has gone up 500% since February, but that is only opinion.
The due dilligence portion of IHANG website has better graphics and is easier to read
WHAT IS AMNIOSTEM?
Amniotic fluid derived stem cell
Issued US patent, licensed from UCSD
Covering composition of matter and practical isolation procedures for amniotic fluid stem cells
“AmnioStem Patent Covers Means to Isolate, Grow and Use Amniotic Fluid Derived Stem Cells in a Scalable and Commercializable Manner”
WHY IS AMNIOTIC FLUID SPECIAL?
Clear, yellowish liquid, surrounds fetus during pregnancy
Continuously inhaled, exhaled by fetus
98% water, proteins, peptides, carbohydrates, lipids and hormones
Protects the developing fetus, promotes growth
AMNIOTIC FLUID STEM CELLS
2001: Atala group postulates existence of c-kit positive stem cells, no means of practical expansion
2003: Prusa et al described stem cell markers in amniotic fluid, no means of expansion
2003: Martin Haas at UCSD (our inventor) Practical protocol for isolation, expansion and growth of amniotic fluid stem cells
2007: First publication on practical use of amniotic stem cells (DeCoppi et al)
“Since 2007 there have been over 600 peer-reviewed publications on the benefits of amniotic fluid stem cells”
AMNIOSTEM IS PRACTICAL STEM CELL THERAPY
Practical protocol for generating therapeutic quality stem cells starting from small (1-5 ml) amniocentesis sample
Do not mutate and maintain phenotype
Large scale expansion of stem cells feasible, with 1 donor generating >20,000 doses
AmnioStem cells do not require matching with recipient (one size fits all)
LOCATION ON THE STEM CELL CONTINUUM
GENERATION OF THERAPEUTIC AMNIOTIC FLUID DERIVED STEM CELLS
ADVANTAGES
Embryonic
Stem Cells Amniotic Fluid Stem Cells Adult
Stem Cells
Developmental potential Pluripotent Pluripotent or multipotent Multipotent
Renewal capacity Very high expansion in cell culture High expansion Limited
Potential for tumor formation Yes No No
Ethical considerations Serious ethical issues raised using embryos No issues; obtained during routine procedures No
What is Amniostem?
Treating Stroke
Pre-Clinical Research
Clinical Research Plan
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Louis Pasteur -- chance favours only the prepared mind.
Lecture, University of Lille (7 December 1854)
Lecture, University of Lille (7 December 1854)