IMPETUS will combine paper, printing and microchip technologies to realize a pilot line in an industrial environment capable of manufacturing fully integrated paper-based electrochemical biosensors that directly transfer the measured data to the user's smartphone. These biosensors will be designed as self-powered disposable test strips that combine the simplicity of lateral flow tests with quantitative readout, which is enabled by the implemented electrochemical detection method. As an application example, IMPETUS will fulfil the consumer need for fast and inexpensive point-of-care discrimination between bacterial and viral infections.
This goal will be achieved by developing new technologies for paper manufacturing, coating and surface modification, and the respective processing will work hand in hand with the ink development (cellulose-based inks for fabricating the printed battery as well as bio-inks for surface functionalization and reagent deposition). A highly integrated and energy efficient silicon microchip will be developed that enables electrochemical signal acquisition, storage and contactless NFC transmission. The microchip will be mounted onto the paper substrate by an inline placement process. Paper will be employed as substrate for the printed circuits and the microchip, but also as active component of the printed battery as well as of the biosensor.
The IMPETUS pilot line will integrate screen-, flexo-, inkjet-printing and an unhoused chip placement in a seamless roll-to-roll process compatible with high throughput fabrication. As result, the pilot line will offer the possibility to be easily adapted for various sensing applications (e.g. medical diagnostics, food safety) accessible to interested third parties after the project end. IMPETUS is a four-year collaborative project, which has received funding from the European Union's Horizon 2020 research and innovation program (topic H2020-PILOTS-05-2017 Paper-based electronics) under grant agreement No 761167. The project has been launched in January 2018 and brings together twelve leading partners with a strong focus on industrialization: three research institutes (AIT Austrian Institute of Technology GmbH, Papiertechnische Stiftung, Technische Universität Chemnitz), two small-medium (Maurer Services GmbH, Saralon GmbH) and seven large enterprises (DPI Holding GmbH, Gwent Electronic Materials Limited, Infineon Technologies Austria AG, Melecs EWS GmbH, R-Biopharm AG, Ricoh UK Products Ltd, Schoeller Technocell GmbH & Co KG). In summary, the IMPETUS pilot line will pave the way towards the real world application of paper-based quantitative electrochemical diagnostic test strips, thereby clearly advancing the current state-of-the-art, which up to now has mostly focussed on individual fabrication processes and device concepts.
AIT Austrian Institute of Technology
The AIT Austrian Institute of Technology is Austria's largest non-university research institute. With its eight Centers, AIT regards itself as a highly specialized research and development partner for industry. Its researchers focus on the key infrastructure issues of the future: Energy, Health & Bioresources, Digital Safety & Security, Vision, Automation & Control, Mobility Systems, Low-Emission Transport, Technology Experience and Innovation Systems & Policy. Throughout the whole of Austria - in particular at the main locations Wien Giefinggasse, Seibersdorf, Wiener Neustadt, Tulln, Graz, Hall in Tirol, Ranshofen and Leoben - around 1,300 employees carry out research on the development of those tools, technologies and solutions that will keep Austria's economy fit for the future in line with our motto "Tomorrow Today".
Contacts:
Fabian Purtscher Marketing & Communications Center for Health and Bioresources AIT Austrian Institute of Technology GmbH fabian.purtscher@ait.ac.at | www.ait.ac.at T +43 (0)50550-4406 | M +43 (0)664 8251322
Mag. Michael H. Hlava Head of Corporate and Marketing Communications AIT Austrian Institute of Technology GmbH Giefinggasse 4 | 1210 Wien michael.h.hlava@ait.ac.at | www.ait.ac.at T +43 (0)50550-4040
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