Quote:Pomegranate: Powerful Support for Cardiovascular Health
May Reverse Atherosclerosis
Human studies of pomegranate juice have demonstrated even more dramatic effects, showing that pomegranate may actually reverse atherosclerosis. Israeli scientists studied patients with narrowing of their carotid arteries as a result of atherosclerosis.7 The carotid arteries in the neck are responsible for more than 80% of blood flow to the brain, and narrowing of these major vessels is a major risk factor for stroke.
Among patients given daily pomegranate juice supplements (providing 78 mg of punicalagins) for one year, atherosclerotic lesions in the common carotid artery decreased by 35% in size, while actually growing by 9% in a control group. Thus, pomegranate reversed existing atherosclerosis, which continued to worsen in those who did not consume pomegranate.
Blood analysis showed that total antioxidant activity increased 130% in the pomegranate juice group, compared to before-treatment values. Finally, the participants’ systolic blood pressure fell by an impressive 21% after one year of pomegranate juice supplementation.
http://www.lifeextension.com/Magazine/2007/5/...te/Page-01
Punicalagins were identified as the most clinically important pomegranate phytochemicals. Punicalagins are highly bioavailable and possess antioxidant activity that greatly exceeds that of many plant-derived antioxidants.45,46 In the most significant clinical studies to date, a daily dose of 78 mg of punicalagins yielded such remarkable benefits as reversing atherosclerosis, reducing high blood pressure, and preventing the adverse cardiovascular consequences of diabetes. 7,8,14 Moreover, an important clinical study demonstrated that 280-375 mg of punicalagins per day halted the progression of prostate cancer in men who had failed conventional therapy.26
Life Extension thus recommends 78 mg of punicalagins per day for cardiovascular protection, and 280-375 mg of punicalagins daily to promote prostate health.
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