From a good poster on IHUB, Fletch falconer66a
Post# of 1460
Fletch
falconer66a Monday, 01/15/18 05:49:24 PM
Re: kevindenver post# 137361
Post # o\f 137370
DNA Whole Exome Sequencing is Big
The gut/brain connection continues to be discovered and explained. Far too much to elaborate on here, except to note that the ability to analyze and discern the DNA signatures of constituent bacteria in the gut (intestine) becomes ever more precise and functional.
With this, it is not unreasonable that in the future (not so distant), a fecal swab would be extracted from a potential patient’s rectum, quickly cultured on an agar plate or in a nutrient broth flask, and the resulting microbes processed to extract and reveal their DNA.
Various microbial DNA signatures may correlate with various dosages and treatment benefits of Anavex sigma-1 receptor agonists; with Anavex 2-73 at the start, or course.
Precision medicine, the careful and precise matching of treatments to diseases and symptoms is rapidly emerging. Last-century throw-a-lot-and-see-what-sticks approaches will become antiquated, replaced with things like gut biome genomic analysis.
Anavex, of course, is doing other precise analyses, matching age classes, symptomologies, and all the other patient data extracted from the Australians in that clinical trial.
Before, drug treatments were pretty much a shotgun approach. Shoot straight and often, a few of the shot have to hit something. Today, with Anavex, it will be precise single-shot, single bullet targeting, at known targets.
The package inserts (or downloadable PDFs) for physicians prescribing Anavex drugs will likely be pretty complex, telling pages of information guiding facilitative and effective dosings. Physicians may have to take an afternoon “course” at a medical conference to learn how to effectively prescribe and monitor Anavex drug usages.
(Or, perhaps just as likely, Anavex 2-73 will prove to be effective and utterly safe in a company-provided list of dosage ranges. A can’t-go-wrong sort of drug.)