Got this back from Leo when I asked him about the
Post# of 72440
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Posted On: 01/03/2018 2:11:41 PM
Got this back from Leo when I asked him about the PR this morning.
Quote:
It's because we reduced incidences of SOM with Brilacidin, too few SOM patients were in the Brilacidin arm to make a statement about reduction that would be mathematically valid. Our primary goal is to prevent patients from getting SOM.
I tried my best to make it clear in the PR.
Duration of Severe Oral Mucositis: Given that Brilacidin-OM successfully prevented SOM from occurring, as well as delayed its onset, in a substantial number of patients, data comparisons aimed at assessing potential reduction in the duration of SOM were constrained by the fewer number of Brilacidin-OM treated patients that could be included in such analysis. While Brilacidin-OM appeared to decrease the initial duration of SOM (time from the initial WHO Grade ≥ 3 to the first WHO Grade ≤ 2 OM assessment), detailed interpretation of this and other duration data comparisons were limited.
Replies:
Thanks!
Jhawker on 1/3/2018 1:56:48 PM
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Quote:
It's because we reduced incidences of SOM with Brilacidin, too few SOM patients were in the Brilacidin arm to make a statement about reduction that would be mathematically valid. Our primary goal is to prevent patients from getting SOM.
I tried my best to make it clear in the PR.
Duration of Severe Oral Mucositis: Given that Brilacidin-OM successfully prevented SOM from occurring, as well as delayed its onset, in a substantial number of patients, data comparisons aimed at assessing potential reduction in the duration of SOM were constrained by the fewer number of Brilacidin-OM treated patients that could be included in such analysis. While Brilacidin-OM appeared to decrease the initial duration of SOM (time from the initial WHO Grade ≥ 3 to the first WHO Grade ≤ 2 OM assessment), detailed interpretation of this and other duration data comparisons were limited.
Replies:
Thanks!
Jhawker on 1/3/2018 1:56:48 PM
Report TOS
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