Dublin, Nov. 06, 2017 (GLOBE NEWSWIRE) -- The "Transdermal Drug Delivery - Technologies, Markets, and Companies" report from Jain PharmaBiotech has been added to Research and Markets' offering.
This report deals with transdermal drug delivery - an approach used to deliver drugs through the skin for therapeutic use as an alternative to oral,intravascular, subcutaneous and transmucosal routes.
Various transdermal drug delivery technologies are described including the use of suitable formulations, carriers and penetration enhancers. The most commonly used transdermal system is the skin patch using various types of technologies. Nanoparticles as well as the use of physical agents to facilitate transcutaneous drug delivery is described. Microneedle and needleless technologies are also described.
Transdermal technologies may be applied for several categories of pharmaceuticals used for the treatment of disorders of the skin or for systemic effect to treat diseases of other organs. Several transdermal products and applications include hormone replacement therapy, contraception, management of pain, angina pectoris, smoking cessation and neurological disorders such as Parkinson's disease. The market for transdermal drug delivery is analyzed according to technologies and therapeutic areas from 2016 to 2026. This market is analyzed according to geographical regions as well.
Key Topics Covered:
Executive Summary 1. Basics of Transdermal Drug Delivery Introduction Historical landmarks in transdermal drug delivery Anatomy and physiology of skin Skin metabolomics and transcutaneous passage of drugs Transcutaneous absorption Transdermal versus other methods of drug delivery Advantages of transdermal drug delivery First-Pass Effect Drawbacks of transdermal delivery Factors that influence transdermal drug delivery Rate of permeation across the skin Properties of the skin Properties of drugs The role of pH and pharmacokinetics Intradermal disposition of drugs after topical application Role of nanobiotechnology in understanding basis of transdermal delivery 2. Transdermal Drug Delivery Technologies Introduction Local application formulations Crystalline topical formulations Microemulsions for transdermal drug delivery Nanoemulsions for transdermal drug delivery Transdermal gel technology Biphasix system Penetration enhancers Chemical enhancers Nitric oxide-based transdermal drug delivery Ionic liquids for transdermal delivery of drugs against bacterial biofilms on skin Vesicular transdermal carriers Liposomes Transfersomes Ethosomes Elastic vesicles for transdermal drug delivery Nanovesicles for transdermal drug delivery Transdermal patches Adhesives for transdermal patches Commercial development of transdermal patches Innovations in transdermal patches e-Patch controlled release micropump system Patchless Transdermal Delivery System Metered-dose transdermal system Polymers for transdermal drug delivery Polymer membranes in transdermal patches Film forming polymeric solutions Use of physical modalities to facilitate transdermal transport Transdermal electrotransport Electroporation Drug delivery by electroporation Cryoelectrophoresis Iontophoresis Iontophoresis compared with electrophoresis Application of iontophoresis for drug delivery Patents in iontophoresis Companies with technologies for drug delivery by iontophoresis Combination of electrophoresis and iontophoresis Dermaportation Radiofrequency-driven transdermal delivery Microporation Transcutaneous drug delivery by electropulsation Companies involved in electroporation-based drug delivery Electrode Scanning System Use of electrostatic force in skin patch technology Multiple Absorption Kinetic System Transdermal drug delivery facilitated by heat Controlled, heat-aided drug delivery Ultrasound Magnetophoresis Use of lasers for transdermal drug delivery Laser-induced microporation Transdermal drug delivery by laser-induced pressure waves Transdermal drug delivery by laser-assisted changes in skin Transdermal delivery by gas under pressure Transdermal delivery with PowderJect gas gun Microscission induced by gas Role of microelectronics in transdermal drug delivery Microneedles and dermal microinjection technologies Applications of microneedles AdminPatch microneedle array Biodegradable microneedles Ceramic microneedle arrays Dissolvable microneedle patches MicorCor Microneedle arrays for drug delivery Microneedle patch MicroPyramid microneedles Microstructured Transdermal Systems Microneedle Array Patch technology Microneedle transdermal chip Microneedle applicator device Nanoject microneedle technology PatchPump Polymer microneedles Silk microneedles Tattooing for drug delivery ZP Patch microprojections technology Companies developing microneedles for transdermal drug delivery Needlefree injections Glide SDI solid dose injector Jet injection Mini-Ject needlefree delivery system MicroJet for painless injections Nanoliter-volume pulsed microjets SUMAVEL DosePro needle-less injection Skin ablation or abrasion for drug delivery Nanotechnology-based transdermal drug delivery Delivery of nanostructured drugs from transdermal patches Effect of mechanical flexion on penetration of bucky balls through the skin Nanobiotechnology for transdermal application Nanoparticles and nanoemulsions for skin disorders Nanopatches Inocyte epidermal drug delivery system Ionic nanoparticle technology SLN gel for treatment of skin disorders Topical delivery of siRNA- nanoparticle conjugates Transdermal nanoparticle preparations for systemic effect Transferosomes for transdermal drug delivery Transdermal administration of nanocarriers Nanotechnology-based transdermal vaccination and immunotherapy Safety issues of applications of nanomaterial carriers on the skin Comparison of transdermal drug delivery systems Transdermal drug design In vitro testing of transdermal drug delivery systems Commercially available skin models for transdermal drug testing FDA guidelines for post-approval changes in semisold topical drugs In vivo testing of drug delivery systems Infrared spectroscopy for evaluation of transdermal drug delivery Modeling of transport through the skin Concluding remarks on transdermal drug delivery technologies Future developments in transdermal drug delivery 3. Transdermal Therapeutics Introduction Drugs that can be administered transdermally Approved transdermal products Drugs in clinical trials Skin disorders Cutaneous leishmaniasis Hair loss Iontophoretic drug delivery for nail disorders Psoriasis Nanoemulsions for paclitaxel delivery in psoriasis Iontophoresis for treatment of psoriasis Cardiovascular disorders Transdermal estrogen for prevention of atherosclerotic cardiovascular disease Transdermal drug delivery for angina pectoris Transdermal drug delivery for hypertension Transdermal clonidine Transdermal delivery of -blockers for hypertension Transdermal delivery of calcium channel blockers for hypertension Transdermal drug delivery for congestive heart failure Transdermal beta blockers Transdermal anticoagulants Respiratory diseases Asthma Chronic obstructive pulmonary disease Neurological and psychiatric disorders Parkinson's disease Transdermal drug delivery for Parkinson's disease Transdermal levodopa delivery systems Transdermal dopamine agonists for Parkinson's disease Rotigotine for Parkinson disease Rotigotine for restless legs syndrome Transdermal administration of other drugs for Parkinson disease Depression Antidepressants Selective serotonin-reuptake inhibitors Transdermal fluoxetine Monoamine oxidase inhibitors Transdermal selegiline Trazodone hydrochloride Venlafaxine Bupropion Bipolar disorder Transdermal lithium Schizophrenia Transdermal haloperidol Transdermal risperidone for treatment of schizophrenia Transdermal blonanserin for treatment of schizophrenia Restless legs syndrome Alzheimer's disease Transdermal rivastigmine Transdermal donepezil Transdermal galantamine Transdermal arecoline Transdermal nicotine for Tourette syndrome Attention deficit hyperactivity disorder Transdermal methylphenidate Migraine Transdermal sumatriptan Transdermal zolmitriptan Epilepsy Tinnitus/Vertigo Transdermal nitroglycerin for vasospasm due to subarachnoid hemorrhage Musculoskeletal disorders Osteoporosis Transdermal alendronate Transdermal estrogen Transdermal human parathyroid hormone Osteoarthritis Transdermal therapy of diabetes Insulin delivery in diabetes by transdermal patches Microneedle patch for glucose-responsive insulin delivery Patch monitoring system for insulin delivery Sonic Applicator & Control Device for TDD of insulin V-Go disposable insulin delivery device ViaDor System for TDD of insulin Companies developing devices for transdermal insulin delivery Transdermal therapy of oral antidiabetic agents Transdermal antidiabetic agents other than insulin Male disorders Erectile dysfunction Topical and transdermal preparation for erectile dysfunction Hypogonadism in the male Topical testosterone Benign prostatic hypertrophy Tamsulosin TDS Women's health Female sexual arousal disorder Menopause Hormone replacement therapy for menopause Effect of transdermal estradiol on bone density Transdermal PTH for postmenopausal osteoporosis Transdermal testosterone for low libido in postmenopausal women Breast disorders Dysmenorrhea Female infertility Contraception Female contraception Ortho Evra AG200-15 BAY86-5016 Desogestrel Male contraception Transdermal progestin plus testosterone Cancer Delivery of the photosensitizer drug d-amino levulinic acid Intradermal delivery of cancer vaccines by adenoviral vectors Nanoemulsion-based delivery of caffeine for skin cancer Topical interferon a2b for cervical cancer and precancerous lesions Transcutaneous electroporation for delivery of anticancer drugs Transdermal delivery of peptide cancer vaccines Transdermal drug delivery for prostate cancer Transdermal nitroglycerine for prostate cancer Transdermal estradiol gel for prostate cancer Transdermal leuprolide acetate for prostate cancer Transdermal drug delivery for breast cancer Afimoxifene topical gel for breast cancer Pain Relief of pain associated with minor medical procedures Transdermal Lidocaine for relief of pain Transdermal Lidoderm? for postherpectic neuralgia Transdermal capsaicin for relief of pain Nonsteroidal antiinflammatory drugs Topical NSAIDs Transdermal ketoprofen Topical opioids Cancer pain Transdermal fentanyl Transdermal nitroglycerine as an adjuvant to opioids Transdermal buprenorphine Chronic pain of non-malignant origin Transdermal local anesthetics Postoperative pain Transdermal fentanyl for the management of postoperative pain Fibromyalgia Nanotechnology-based approved transdermal analgesic preparations Nausea and vomiting Motion sickness Postoperative vomiting Chemotherapy-induced nausea and vomiting Antiaging strategies Smoking cessation Transdermal nicotine replacement Use of nicotine patch for smoking cessation in pregnancy Other methods of nicotine replacement Other treatments for smoking cessation Miscellaneous uses of transdermal drug delivery Chronic fatigue syndrome Overactive bladder and urinary incontinence Transdermal oxybutynin Viral infections Transdermal nanoparticles for immune enhancement in HIV Transdermal IQP-0410 for HIV/AIDS Wound healing and ulcers Transdermal gene therapy Transdermal delivery of plasmid DNA by electroporation Transdermal antisense therapy Transdermal vaccination The skin as an immune organ Technologies for transdermal vaccination Dissolvable microneedle array for vaccine delivery Electroporation for administering DNA vaccines Microneedles for transdermal delivery of vaccines Needle-free delivery of vaccines Transcutaneous immunotherapy using nanodispersions Applications of transdermal vaccination HIV/AIDS vaccination by topical application Transdermal DNA influenza vaccine Transdermal A vaccination for Alzheimer's disease Transdermal vaccination for traveller's diarrhoea Transdermal nutraceuticals Complications of transdermal therapy Adverse effects of drugs Overdose effect Skin complications MRI-induced skin burns from transdermal patches 4. Markets for Transdermal Drug Delivery Introduction Global markets for drug delivery Geographical distribution of transdermal drug delivery markets Emerging transdermal drug delivery markets in Asia Transdermal technology markets in therapeutic areas Angina pectoris Attention deficit hyperactivity disorder Erectile dysfunction Hypertension Osteoporosis Pain therapeutics Parkinson's disease Smoking cessation Transdermal hormone replacement therapy for menopause Transdermal testosterone replacement therapy for hypogonadism in the male Transdermal contraceptive market Markets according to transdermal technologies Markets for microneedle-based transdermal drug delivery Marketing strategies for transdermal drug delivery Marketing advantages of transdermal drug delivery Unmet needs in transdermal drug delivery Regulatory aspects that affect transdermal drug delivery markets Future prospects of transdermal drug delivery Growth of new technologies used in transdermal drug delivery Prospects of transdermal delivery for drugs coming off patents Transdermal delivery of biologicals Transdermal delivery of cosmetics 5. Companies involved in transdermal drug delivery Profiles of companies Top companies in transdermal drug delivery Collaborations
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