$TXTM In modifying its research protocols, the Company cited seventeen previously published randomized human trials with green tea catechins that demonstrated favorable effects with glucose control and insulin sensitivity through decreased fasting glucose and Hb A1c concentrations. A further fourteen studies confirmed that catechins are effective in lowering LDL cholesterol and in reducing fatty deposits around the liver and pancreas. In addition, recent investigations at seven Japanese medical institutions established that catechins reduce body fat and cardiovascular risks. In addition, mouse model studies have shown that the auto-immune protective properties of catechins are effective in reducing the onset of Type 1 diabetes. Despite all these clinical investigations and positive findings regarding catechins and diabetes, the universal conclusion is that low bioavailability (absorption) and high daily dosage requirements remain the limiting factors to green tea becoming a primary diabetes therapy. In the case of Type 1 diabetes, a study must be undertaken to determine if green tea catechins can be used at the latent autoimmune stage, before the diabetes starts destroying pancreatic beta cells. For green tea catechins to become effective pharmaceutical alternative medicines, the barriers of solubility, permeability, metabolism, excretion, target tissue uptake, and disposition must be overcome.
https://finance.yahoo.com/news/protext-pharma...58561.html
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