Article - Chemotherapy-Induced and Radiotherapy-In
Post# of 72440
"Between 20% and 40% of patients treated with conventional chemotherapy will develop mucositis compared with approximately 80% of patients who receive high-dose myeloablative chemotherapy prior to hematopoietic stem cell transplant (HSCT) and 100% of patients who undergo radiotherapy for head and neck cancer (HNC) ."
Conclusion
"Oral mucositis is a potentially life-threatening complication of radiotherapy or chemotherapy. In addition to severe pain and a negative effect on quality of life, OM increases the risk of infection, hospitalizations, and therapy discontinuation. Treatment options consist primarily of oral rinses, which are relatively safe but have limited evidence for their effectiveness. A better understanding of the pathogenesis and risk factors for OM may lead to the development of novel agents that are more effective at preventing or treating the condition."
http://www.cancertherapyadvisor.com/side-effe...le/651633/