Believe I finally found out why Dr. Menon decided
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Posted On: 08/24/2017 6:15:13 PM
Believe I finally found out why Dr. Menon decided to try Abacavir (Prurisol is Abacavir Acetate) as a treatment for Psoriasis.
Summary. Abacavir is a type of antiretroviral drug called a nucleoside analogue (“nuke”)
https://www.google.com/url?sa=t&rct=j&...iNzhtG98Ug
Antiretroviral Treatment
Exacerbation of psoriasis lesions with increasing degrees
of immunosuppression suggested antiretroviral treatment
as a therapeutic strategy. With the introduction of the first
drugs that acted specifically against HIV (with zidovudine
[AZT] as the only such drug available), several cases were
reported of partial improvement of psoriasis lesions that
had previously been refractory to other treatments.33 The
drug was shown to be useful and safe, though its mechanism
of action against psoriasis was unknown.
https://pdfs.semanticscholar.org/9549/def0453...542d15.pdf
Summary. Abacavir is a type of antiretroviral drug called a nucleoside analogue (“nuke”)
https://www.google.com/url?sa=t&rct=j&...iNzhtG98Ug
Antiretroviral Treatment
Exacerbation of psoriasis lesions with increasing degrees
of immunosuppression suggested antiretroviral treatment
as a therapeutic strategy. With the introduction of the first
drugs that acted specifically against HIV (with zidovudine
[AZT] as the only such drug available), several cases were
reported of partial improvement of psoriasis lesions that
had previously been refractory to other treatments.33 The
drug was shown to be useful and safe, though its mechanism
of action against psoriasis was unknown.
https://pdfs.semanticscholar.org/9549/def0453...542d15.pdf
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