I just noticed that a lot more specific detail was

I just noticed that a lot more specific detail was added to the patent claims between when Bayer applied for the application and when QMC was granted the application.

Quote:

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1. A continuous-flow method for preparing InP/ZnS nanoparticles conducted in a micro-reaction system comprising at least one mixing chamber connected to one reaction chamber, said method comprising:
preparing an indium precursor solution by mixing an indium salt, a fatty protic alkylamine, a fatty alkylacid, and zinc carboxylate with an inert solvent and heating up to 50-200° C. to get a clear solution under water and oxygen free atmosphere;
preparing a phosphine precursor solution comprising tris(trimethylsilyl) phosphine in the inert solvent under water and oxygen free atmosphere;
injecting the indium precursor solution in excess to the phosphine precursor solution into the mixing chamber to obtain a reaction mixture, wherein the mixing chamber is a magnetic mixing micro-chamber with a volume in the range of 10 mm3 to 10,000 mm3, and wherein the injecting is at a flow rate from 0.1 ml/min to 10 ml/min;
forwarding and heating the reaction mixture at a temperature from 160 to 320° C., within the reaction chamber until InP core suspension is obtained;
forwarding the core suspension into a mixing chamber and injecting a shell precursor solution comprising a Zn source and a S source to the core suspension and capping ligands into the mixing chamber;
forwarding and heating the suspension at a temperature from 160 to 320° C. for shell preparation within the reaction chamber; and cooling.
2. The continuous-flow method of claim 1, wherein the Zn source and the S source is a single source.
3. The continuous-flow method of claim 1, wherein the mixing chamber is a magnetic mixing micro-chamber with a volume in the range of 30 mm3 to 70 mm3.
4. The continuous-flow method of claim 1, wherein the reaction chamber has an inner diameter in the range of 0.1 mm and 2 mm and a length in the range of 0.5 m to 20 m.
5. The continuous-flow method of claim 1, wherein the forwarding and heating of the reaction mixture within the reaction chamber until InP core suspension is obtained is at a temperature from 200 to 280° C.
6. The continuous-flow method of claim 1, wherein all operations are completed in less than one hour.

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Granted patent
https://www.google.com/patents/US9577149?dq=%...sQ6AEIKDAA

Quote:

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1. Continuous-flow method for preparing InP/ZnS nanoparticles conducted in a micro-reaction system comprising at least one mixing chamber connected to one reaction chamber and said method comprising:
a. Preparing an indium precursor solution by mixing an indium salt, a fatty protic alkylamine, a fatty alkylacid and zinc carboxylate with an inert solvent optionally heating up to 50-200° C. to get a clear solution under water and oxygen free atmosphere,
b. Preparing a phosphine precursor solution comprising tris(trimethylsilyl) phosphine in the inert solvent under water and oxygen free atmosphere,
c. Injecting the indium precursor solution in excess to the phosphine precursor solution into the mixing chamber to obtain a reaction mixture, wherein the mixing chamber is a magnetic mixing micro-chamber, optionally at a flow rate from 0.1 ml/min to 10 ml/min,
d. Forwarding and heating the reaction mixture at a temperature from 160 to 320° C., within the reaction chamber until InP core suspension is obtained,
e. Forwarding the core suspension into a mixing chamber and injecting a shell precursor solution comprising a Zn source and a S source to the core suspension and optionally capping ligands into the mixing chamber,
f. Forwarding and heating the suspension at a temperature from 160 to 320° C., optionally 200 to 280° C. for shell preparation within the reaction chamber,
g. Cooling.
2. Method according to claim 1 wherein Zn source and S source is a single source.
3. InP/ZnS nanoparticle obtainable by the method of claim 1.
4. Formulation comprising the nanoparticle of claim 3.
5. Device comprising the nanoparticle of claim 3.

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Application
https://www.google.com/patents/US20140326921?...oration%22