It's possible that lower doses over a longer perio
Post# of 72440
You don't have to have 100% efficacy for a drug to be approved. Drugs for diseases like rheumatoid arthritis have a high failure rate.
Prurisol has a much better safety profile that the other drugs that they are comparing it to.
And as I have said over and over again like a broken record (which some of our younger posters have never experienced ), doctors typically prescribe the least dangerous drug FIRST, then progress to more dangerous drugs if that drug doesn't work. So if Prurisol has efficacy that is even slightly inferior to the biologics, doctors will want to try that on patients first.
When I read the list of possible side effects for biologics, it's pretty horrifying.