"For administration to human patients, the total d

"For administration to human patients, the total daily dose of the active compounds is anticipated to be in the range of 1 mg to 300 mg per kg of body weight, depending on the mode of administration. For example, oral administration may require a total daily dose of from 100 mg to 300 mg per kg of body weight, while an intravenous dose may only require from 20 mg to 200 mg per kg of body weight. The total daily dose may be administered in single or divided doses. For an average human subject having a weight of about 70 kg, the dosage would be about 1400 mg to 21000 mg for oral administration and about 140 mg to 1400 mg for intravenous administration. The physician will readily be able to determine doses for subjects whose weight falls outside this range, such as infants and the elderly. A veterinarian will readily be able to determine doses for other mammals."