F1ash posted the attached article regarding a 2009
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Posted On: 07/01/2017 9:25:58 PM
F1ash posted the attached article regarding a 2009 article about Brilacidin and how it KILLS malaria. The 2 paragraphs below are excerpts from the article linked beneath the paragraphs.
Due to so many malaria cases being from extremely poor areas such as Sub-Sahara Africa and SE Asia, the revenues may not be there but the need is great and maybe someday the UN might actually get off their ass and do something positive and provide B as malaria kills 1 in 5 Sub-Saharan children.
"Dr. Greenbaum recently reported that small molecule defensin-mimetic compounds discovered by Radnor, Penn.-based biopharmaceutical company PolyMedix, irreversibly kill P. falciparum while sparing human red blood cells. Plasmodium species are responsible for the nearly five hundred million cases of malaria worldwide and as many as two million deaths, most of them in children. As with antimicrobial agents, first-line malaria agents are losing effectiveness due to development of resistance to drugs by the target organisms.
Dr. Greenbaum demonstrated that PolyMedix's compounds kill P. falciparum irreversibly, meaning the cells do not recover when the agent is depleted. Irreversible killing distinguishes a "cidal," or true killing mechanism, from a "static" mechanism that holds the infectious agent at bay while the body's immune system fights off the infection. "If we treat for ten hours and remove the compound, the parasites never recover," notes Dr. Greenbaum. Many antimicrobial and antifungal drugs are of the static variety."
http://newswise.com/articles/new-malaria-drug...ays-expert
Due to so many malaria cases being from extremely poor areas such as Sub-Sahara Africa and SE Asia, the revenues may not be there but the need is great and maybe someday the UN might actually get off their ass and do something positive and provide B as malaria kills 1 in 5 Sub-Saharan children.
"Dr. Greenbaum recently reported that small molecule defensin-mimetic compounds discovered by Radnor, Penn.-based biopharmaceutical company PolyMedix, irreversibly kill P. falciparum while sparing human red blood cells. Plasmodium species are responsible for the nearly five hundred million cases of malaria worldwide and as many as two million deaths, most of them in children. As with antimicrobial agents, first-line malaria agents are losing effectiveness due to development of resistance to drugs by the target organisms.
Dr. Greenbaum demonstrated that PolyMedix's compounds kill P. falciparum irreversibly, meaning the cells do not recover when the agent is depleted. Irreversible killing distinguishes a "cidal," or true killing mechanism, from a "static" mechanism that holds the infectious agent at bay while the body's immune system fights off the infection. "If we treat for ten hours and remove the compound, the parasites never recover," notes Dr. Greenbaum. Many antimicrobial and antifungal drugs are of the static variety."
http://newswise.com/articles/new-malaria-drug...ays-expert
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