Moleculin Biotech, Inc., (NASDAQ: MBRX) shares hav
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Janssen Research & Development (JNJ) announced that the FDA has assigned a PDUFA date under priority review of October 28, 2017 for the supplemental New Drug Application (sNDA) of XARELTO (rivaroxaban) to include a 10 mg once-daily dose for reducing the risk of VTE after at least six months of standard anticoagulant therapy.
Akebia Therapeutics, Inc. (NASDAQ:AKBA) announced the pricing of an underwritten public offering of 4,000,000 shares at a price of $14.50 per share. Shares closed the after-hours session down 4.7% to $14.78.
Gemphire Therapeutics Inc.(NASDAQ:GEMP) announced that it met the primary endpoint from its Phase 2b COBALT-1 trial. COBALT-1 evaluated gemcabene in homozygous familial hypercholesterolemia (HoFH) patients who are on stable maximally tolerated lipid-lowering therapies to assess the efficacy, safety, and tolerability of multiple rising doses of gemcabene. Gemcabene 300 mg lowered LDL-C by a mean of 25% (p=0.0063; range -55% to +1%), while the 600mg and 900mg doses lowered LDL-C by a mean of 30% (p=0.0047) and 29% (p=0.0035), respectively. Shares closed the after-hours session up 10% to $13.50.
Major price movers (stocks priced > $1.00, volume > 100k):
ADVANCERS:
Cascadian Therapeutics Inc (NASDAQ:CASC): $4.26; +18%.
DelMar Pharmaceuticals Inc (NASDAQMPI): $2.36; +17%.
Ra Pharmaceuticals Inc (NASDAQ:RARX): $19.88; +12%.
Fibrocell Science Inc (NASDAQ:FCSC): $4.31; +10%.
Merrimack Pharmaceuticals Inc (NASDAQ:MACK): $1.40; +10%.
DECLINERS:
Flex Pharma Inc (NASDAQ:FLKS): $3.82; -10%.
Alder Biopharmaceuticals Inc (NASDAQ:ALDR): $12.15; -10%.
Omeros Corporation (NASDAQ:OMER): $20.34; -9%.
Matinas BioPharma Holdings Inc (NYSEMKT:MTNB): $1.67; -8%.
Minerva Neurosciences Inc (NASDAQ:NERV): $7.95; -8
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