One theory that conforms with this is the idea tha

One theory that conforms with this is the idea that the amyloid plaques are the body's way of trying to stop the destructive process -- sealing things off -- and that by forcibly removing them, it's like ripping off a Band-Aid. The "bleeding" starts again. In other words, the plaques are a symptom, not a cause.

This idea certainly has merit, given that many of the supposed plaques-attacking medicines make patients dramatically WORSE in clinical trials.

I have been saying for years that everyone was going after the effect (amyloid plaques) instead of the cause (whatever it is). I hope that AVXL or NTRP or some other company that we don't know about yet (or PRAN?) comes up with a drug or drugs that help. It would be great if some of the different approaches these companies are taking turned out to be complementary therapies, so that a combo dosing could halt and reverse this horrible disease.