SLC again re P:
slcimmuno Member Level Saturday, 05/13/17 08:35:07 PM
Re: biodoc post# 181868
Post # of 181920
Would be nice, for sure, to see the 12wk results carry over to the 16wk re-check--P showing staying power. Always appreciate your input too. Maybe more of us geezers (as in: how long we've been in the stock) can start piping up, change the content and tone of this board for the better.
Truth be told, re itching (pruritus), I think Brilacidin has more/the most potential in treating numerous Derm indications (as a topical). This article goes to HDP MOA and skin disease.
"Novel Insight Into the Role of Antimicrobial (Host Defense) Peptides/Proteins in Human Skin Diseases"
https://www.jstage.jst.go.jp/article/jmj/62/2...0/_article
Just need to get the formulation done and start testing away in eczema, acne, h suppurative, etc.
With limited systemic absorption but what looks like early Kick-A efficacy in UPS (IBD... as an enema) and OM (swish/spit) bodes well for Brilacidin more broadly topically applied. Also that it has antibacterial properties should help as Atopic Derm and H.S. have a strong infection component to their etiology.
Just need that first kaching deal to supercharge Dev, either solo or with Big Rx. Drugs are v hard to come-by--formulation the much easier part of the equation.
slcimmuno Member Level Saturday, 05/13/17 08:35:07 PM
Re: biodoc post# 181868
Post # of 181920
Would be nice, for sure, to see the 12wk results carry over to the 16wk re-check--P showing staying power. Always appreciate your input too. Maybe more of us geezers (as in: how long we've been in the stock) can start piping up, change the content and tone of this board for the better.
Truth be told, re itching (pruritus), I think Brilacidin has more/the most potential in treating numerous Derm indications (as a topical). This article goes to HDP MOA and skin disease.
"Novel Insight Into the Role of Antimicrobial (Host Defense) Peptides/Proteins in Human Skin Diseases"
https://www.jstage.jst.go.jp/article/jmj/62/2...0/_article
Just need to get the formulation done and start testing away in eczema, acne, h suppurative, etc.
With limited systemic absorption but what looks like early Kick-A efficacy in UPS (IBD... as an enema) and OM (swish/spit) bodes well for Brilacidin more broadly topically applied. Also that it has antibacterial properties should help as Atopic Derm and H.S. have a strong infection component to their etiology.
Just need that first kaching deal to supercharge Dev, either solo or with Big Rx. Drugs are v hard to come-by--formulation the much easier part of the equation.
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