Stockholm, 22 September 2016. Nuevolution AB (publ) (NUE.ST) will today present preclinical and preliminary toxicology data from its BET BD1 program at Discovery on Target 2016 (DoT 2016) in Boston, MA, USA. Jimmi G. Seitzberg, Project Manager, Nuevolution, will give an oral presentation reporting the key findings from the poster “NUE7770 - A BET-BD1 selective chemical probe with potent cellular and in vivo anti-inflammatory activity”, also including preliminary data from the first comparative animal toxicology study with NUE7770, selective BET BD1 inhibitor. The preliminary data from a two-week mouse toxicology study with Nuevolution’s selective BET inhibitor NUE7770 showed no mortality and no loss in body weight even at high doses of the compound, whereas the non-selective BET control compound, JQ1, showed a high mortality already at lower doses. The final conclusion from this toxicology study is not yet available as further studies still are ongoing. A full characterisation and conclusion from this comparative animal toxicology study will be available in the fourth quarter 2016. NUE7770 is also being tested in mouse models of Systemic Lupus Erythematosus (SLE) and Idiopathic Lung Fibrosis (IPF), severe inflammatory diseases. Data from these studies will be reported later in 2016. For more information, please contact: Thomas Franch, CSO Phone: +45 7020 0987 Email: tf@nuevolution.com Henrik D. Simonsen, CFO Phone: +45 3913 0947 Email: hs@nuevolution.com About bromodomain proteins BET bromodomain proteins play an important role in regulation of gene expression, which thereby affect inflammatory responses and the ability of cancer cells to sustain growth and survive. The human proteome comprises 46 bromodomain-containing proteins, many of which are thought to be involved in cancer, inflammation and cardiovascular disease. About Nuevolution Nuevolution AB (publ) is a leading small molecule drug discovery biotech company founded in 2001, headquartered in Copenhagen, Denmark. Nuevolution partners its proprietary discovery platform and programs with pharmaceutical and biotechnology companies to seek future benefit of patients in need of novel medical treatment options. Nuevolution’s internal programs are focused on therapeutically important targets within inflammation, oncology and immuno -oncology. Nuevolution AB (publ) is required to disclose the information provided herein pursuant to the Securities Markets Act. The information was sent for publication on Thursday 22 September 2016, 18:10 (CEST). Nuevolution AB (publ) is listed at Nasdaq First North Premier in Stockholm, Sweden (ticker: NUE.ST). Västra Hamnen Corporate Finance AB acts as Certified Adviser to Nuevolution AB (publ). More information about Nuevolution can be found on: www.nuevolution.com
Oral presentation of preclinical and preliminary toxicology
Top 10 Most Recent News Articles
Elevest Unveils MADE: Shaping Wealth for Athletes, Artists
Turning Talent Into Tangible Wealth Ask any musician or athlete, and they'll tell you—riding those career highs is exhilarating, but financial stability can be a different ballgame. Here comes Elevest Capital with a fresh move meant to set the players right where many falter: long-term ownership. They're rolling out MADE, a new initiative focused on flipping that burst...
Continue Reading
Rutter Mills Secures $13M in Virginia Injury Cases
The Stakes in Virginia When you drop nine successful injury cases on the scales and they tip over $13 million, that's a story worth dissecting. The two top dogs at Rutter Mills certainly know how to make a splash in the legal puddle, don't they? We're talking about attorneys Adam H. Lotkin and Georgina D. Montgomery here, the legal eagles behind these jaw-dropping...
Continue Reading
Morphe’s Auction Hits High Notes with Fine Jewelry
Luxurious Gems Steal the Spotlight When the gavel dropped at Morphy's Fine Jewelry & Watches Auction, it set the stage for a spectacular showcase of opulent treasures. The event, highlighting 632 lots and tallying over $1.8 million in sales, left bidders buzzing in anticipation of their next chance to snag a slice of elegance. Bvlgari's Serpentine Charm In the spotlight...
Continue Reading
Ajman Tourism Department Hits Internal Audit Milestone
A Nod to Standards in Ajman's Tourism Department Folks, it's not every day you see a government department get this kind of spotlight in the internal audit arena, yet here we are. The Ajman Department of Tourism, Culture and Media has snagged Full Conformance with Internal Audit Quality Standards. That’s not just some random feather in their cap but a signal flare in...
Continue Reading
Newfold Digital Revamps Leadership for Growth Surge
Steering into New Horizons with Fresh Leadership October 2026 marks a fresh chapter for Newfold Digital, as they shuffle the deck chairs a bit and ramp up for some ambitious growth endeavors. This web and commerce tech company decided it's time to bring a few heavy hitters on board. Starting this month, watch out for Sachin Puri taking the reins as Chief Executive...
Continue Reading
Moore, Schulman & Moore Attorneys Earn Top Honors Again
In the realm of family law, consistency in excellence matters just as much as landing a high-stakes stock trade. Moore, Schulman & Moore, APC, a San Diego family law outfit, has grabbed the spotlight yet again with nine of its ace attorneys snagging recognition from the 2027 Super Lawyers roster. A Tradition of Professional Recognition Leading the pack is Erik Moore, a...
Continue Reading
Teamsters Secure Landmark Deal for SF Parking Workers
Major Win for San Francisco's Parking Professionals Parking lots and garages across San Francisco might not be the first places you’d look for labor triumphs, but that’s exactly what almost 1,000 members of Teamsters Local 665 have achieved. Under a newly ratified four-year master contract, these parking pros snagged one of the richest deals the industry has seen. A...
Continue Reading
AI Visibility: A Game Changer for SEO in 2027?
AI Changes the SEO Game Rank Math, the brains behind a trusty WordPress SEO plugin, has thrown a bold prediction at us: AI visibility is set to become a standard SEO metric next year. Gurugram, India, saw this gem of an announcement on October 9, 2026. So, what's ticking here? Consumers, more than ever, are resting on AI-generated answers to make decisions. It's like...
Continue Reading
STRATA Showcases Excimer Laser Success in Dermatology
The Cutting Edge of Skin Care: STRATA's Spotlight It's not every day you hear about dermatology shaking things up, but STRATA Skin Sciences, Inc. pulled it off with flair at the 2026 Fall Clinical Dermatology Conference in Las Vegas. For 'skin in the game,' these folks are leading the charge with their innovative excimer laser phototherapy approach, shining a fresh light...
Continue Reading
Ingram Mercantile's Aviation Push: SCORE or Sink?
Unpacking Neobanx's Strategic Play Straight off the tarmac, Neobanx launches Ingram Mercantile, placing their bets on the aviation sector with none other than Eli Stepp at the helm. This ain't just another day in the sky for those in the know; it's part of a gutsy bid to inject some high-octane intelligence into the world of retail. I mean, have you seen the landscape...
Continue ReadingTop 5 Most Recently Viewed Articles
Prospects of Bulk Bag Dischargers Market Growth by 2034
Insights into the Bulk Bag Dischargers Market The global bulk bag dischargers market, currently valued at USD 201.2 million, is forecasted to reach USD 272.9 million by 2034. This growth trajectory emphasizes a compound annual growth rate (CAGR) of 2.9% from 2024 to 2034, driven primarily by the increasing demand for automated systems that enhance efficiency in material...
Continue Reading
Cousins Properties Shows Strong Growth in Recent Quarter Results
Cousins Properties Announces Third Quarter Results Cousins Properties (NYSE: CUZ) has revealed robust numbers for its third quarter results. The latest financial disclosures showcase the company's ongoing success and stability as it navigates a competitive real estate market. Key Financial Highlights The financial report indicates significant growth in rental income and...
Continue Reading
Key Insights on RAM Pavement's Waxhaw Roundabout Project Investment
The Big Picture on RAM Pavement's Move Every once in a while, something pops up that takes me back to the days of big economic shifts—and this Waxhaw roundabout project is one of those moments. RAM Pavement wrapped up critical improvements to a roundabout that folks are buzzing about. They claim it’ll enhance traffic flow and public safety, and, honestly, with the...
Continue Reading
STRADVISION Unveils Groundbreaking Data Management Workflow
STRADVISION Introduces an Innovative Data Management Workflow STRADVISION, renowned for its cutting-edge deep learning-based vision perception technology, has made waves with the introduction of its Data Management Workflow. This advanced solution is specifically crafted to enhance the development and mass production of the SVNet 3D Perception Network, a significant leap...
Continue Reading
Sunrise New Energy Expands Presence at North America's Biggest Battery Show
Sunrise New Energy Attends The Battery Show North America Sunrise New Energy Co., Ltd. (NASDAQ: EPOW) is taking bold steps to enhance its footprint in the energy storage market. Led by CEO Mr. Haiping Hu, the company is attending The Battery Show North America 2025. This prestigious event takes place in Detroit and is recognized as the largest battery exhibition in North...
Continue Reading