DGAP-PVR: SYGNIS AG: Release according to Article 26,

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News Desk 2018
DGAP-PVR: SYGNIS AG: Release according to Article 26, Section 1 of the WpHG [the German Securities Trading Act] with the objective of Europe-wide distribution

SYGNIS AG 08.08.2016 17:00 Dissemination of a Voting Rights Announcement, transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement. --------------------------------------------------------------------------- Notification of Major Holdings 1. Details of issuer SYGNIS AG Waldhofer Str. 104 69123 Heidelberg Germany 2. Reason for notification Acquisition/disposal of shares with voting rights Acquisition/disposal of instruments X Change of breakdown of voting rights Other reason: 3. Details of person subject to the notification obligation Name: City and country of registered office: Genetrix S.L. Madrid Spain 4. Names of shareholder(s) holding directly 3% or more voting rights, if different from 3. 5. Date on which threshold was crossed or reached 02 Aug 2016 6. Total positions % of voting % of voting rights total of total number rights attached through instruments both in % of voting to shares (total (total of 7.b.1 + (7.a. + rights of of 7.a.) 7.b.2) 7.b.) issuer Result- 15.50 % 8.15 % 23.65 % 21622091 ing situat- ion Previo- 19.95 % 10.48 % 30.43 % / us notifi- cation 7. Notified details of the resulting situation a. Voting rights attached to shares (Sec.s 21, 22 WpHG) ISIN absolute in % direct indirect direct indirect (Sec. 21 WpHG) (Sec. 22 WpHG) (Sec. 21 WpHG) (Sec. 22 WpHG) DE000A1RFM03 3351496 15.50 % % Total 3351496 15.50 % b.1. Instruments according to Sec. 25 para. 1 No. 1 WpHG Type of Expiration or Exercise or Voting Voting instrument maturity date conversion rights rights in period absolute % % Total % b.2. Instruments according to Sec. 25 para. 1 No. 2 WpHG Type of Expiration Exercise or Cash or Voting Voting instrument or maturity conversion physical rights rights date period settlement absolute in % Right to Physical 1761466 8.15 % recall lent securities Total 1761466 8.15 % 8. Information in relation to the person subject to the notification obligation X Person subject to the notification obligation is not controlled and does itself not control any other undertaking(s) holding directly or indirectly an interest in the (underlying) issuer (1.). Full chain of controlled undertakings starting with the ultimate controlling natural person or legal entity: Name % of voting rights % of voting rights Total of both (if (if at least held 3% through instruments (if at least held 5% or more) at least held 5% or more) or more) 9. In case of proxy voting according to Sec. 22 para. 3 WpHG Date of general meeting: Holding position after general meeting: % (equals voting rights) 10. Other explanatory remarks: 08.08.2016 The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Archive at www.dgap.de --------------------------------------------------------------------------- Language: English Company: SYGNIS AG Waldhofer Str. 104 69123 Heidelberg Germany Internet: www.sygnis.com End of Announcement DGAP News-Service ---------------------------------------------------------------------------

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