In this paper, we report the use of submerged micr

In this paper, we report the use of submerged microsphere optical nanoscopy (SMON) for the direct imaging of an adenovirus with a diameter of 75 nm at a resolution beyond the optical diffraction limit. Large-diameter (100 µm) BaTiO3 spheres were used for this submerged optical imaging. The mechanisms involved in the dual-light large-microsphere submerged optical imaging are described.

http://www.nature.com/lsa/journal/v2/n9/full/lsa201360a.html