Neurotrope Inc (NTRP) 0.4500 $NTRP Neurotrope announces

New Post Public Reply Private Reply Replies (0) Message Board
Stock_Tracker
Neurotrope Inc (NTRP) 0.4500 $NTRP

Neurotrope announces that a new study published in the Journal of Biological Chemistry shows that Bryostatin, a PKC epsilon Activator, Generates New Synapses Through Accumulation of the Synaptic Anchoring Protein PSD-95 at Neuronal Membranes
PR Newswire - Thu Jun 23, 7:30AM CDT
Neurotrope, Inc. (OTCQB: NTRP) today announced that a study published in the Journal of Biological Chemistry shows that its lead Alzheimer's drug, Bryostatin, licensed from the Blanchette Rockefeller Neurosciences Institute (BRNI), increases the levels of the synaptic scaffolding protein PSD-95, and induces the movement of phosphorylated PSD-95 to the neuronal membranes. The study, conducted within the BRNI basic research programs, showed that Bryostatin induced activation of PKC epsilon increased synaptic number, pre-synaptic vesicle density, and clusters of PSD-95. It is known that either AB or tau, both toxic proteins in Alzheimer's disease brains, can induce reduction of PSD-95 in excitatory synapses in hippocampus. Furthermore, this PSD-95 reduction continues to occur as the Alzheimer's pathologies advance. A Phase 2b clinical trial funded by Neurotrope Bioscience, Inc., Neurotrope, Inc.'s wholly-owned subsidiary, is underway to test the efficacy of Bryostatin for the treatment of the causes and progression of Alzheimer's disease.

Neurotrope Appoints Paula T. Trzepacz, M.D. as Executive Vice President and Chief Medical Officer
PR Newswire - Tue Jun 21, 7:30AM CDT
Neurotrope, Inc. (OTCQB: NTRP): today announced that Paula T. Trzepacz, M.D., has joined Neurotrope BioScience, Inc., the Company's wholly owned operating subsidiary, as its Executive Vice President and Chief Medical Officer.

Neurotrope's Chief Scientific Officer Dr. Daniel Alkon Presents at the Gordon Conference: Drugs That Target Common Mechanisms for Synaptic Restoration in Mental Retardation and Alzheimer's Disease
PR Newswire - Mon Jun 13, 7:30AM CDT
Neurotrope, Inc. (OTCQB: NTRP): Dr. Daniel Alkon, Chief Scientific Officer of Neurotrope, discussed "Modulation of PKC Epsilon as a Therapeutic Strategy" as a potential treatment for both Fragile X mental retardation and Alzheimer's disease at the Autism-Related Disorders Gordon Conference.

Neurotrope Enters Into Research Collaboration With the International Rett Syndrome Foundation / Rettsyndrome.org
PR Newswire - Thu May 19, 7:30AM CDT
Neurotrope, Inc. (OTCQB: NTRP), a clinical-stage company developing a disruptive therapy for the treatment of severe Alzheimer's disease (AD), is pleased to announce that it has entered into a research collaboration with the International Rett Syndrome Foundation, DBA: Rettsyndrome.org, to explore the potential of Bryostatin for the treatment of Rett syndrome.

Neurotrope Announces Publication Demonstrating Synaptic Regeneration with the PKC epsilon Activator Bryostatin, in a Fragile X Disease Late Brain Development Model
PR Newswire - Tue Mar 08, 7:30AM CST
Neurotrope, Inc. (OTCQB: NTRP) today announced that its lead Alzheimer's drug Bryostatin improved disease symptoms and restored normal synaptic networks in a young transgenic animal model of Fragile X Syndrome (FXS), a common genetic cause of mental retardation and autism. The study led by scientists at the Blanchette Rockefeller Neuroscience Institute (BRNI) demonstrated that chronic treatment with bryostatin-1 rescues young fragile X mice (corresponding to 15 - 16 year old children) from the disorder phenotypes, including reversal of most FXS abnormalities of 1) hippocampal brain-derived neurotrophic factor (BDNF) expression, 2) the synaptic anchoring protein, PSD-95, levels, 3) transformation of immature dendritic synapses to fully mature, developed synapses, 4) sub-cellular densities of the presynaptic and postsynaptic membranes, and 5) spatial learning and memory. These results were long lasting and confirmed by electron microscopy. While other attempts at Fragile X therapeutics have focused on reduced mGluR5 receptor levels, the Bryostatin efficacy for treating Fragile X did not require changes of mGluR5 and were even more dramatic than those of a late-onset treatment in adult Fragile X mice. As a result of the mutation of the FMR1 gene, the Fragile X mental retardation protein (FMRP) is not produced. It is known that this protein is abundant in the neurons of the hippocampus and cerebellum of non-affected individuals, but it is not yet fully understood why the absence of FMRP results in the phenotype of Fragile X. We have found that chronic activation of PKC in the hippocampus by Bryostatin can rescue synapses and spatial cognition, as well as other FXS phenotypes. This rescue in Fragile X mice is remarkably similar to the rescue of synapses, spatial cognition, and other Alzheimer's disease (AD) phenotypes in AD transgenic mice. The new Fragile X study in late brain development is entitled "Rescue of Synaptic Phenotypes and Special Memory in Young Fragile X Mice," was authored by Miao-Kun Sun, Jarin Hongpaisan, and Dr. Daniel L. Alkon, and is published, in the Fast Forward edition of the Journal of Pharmacology and Experimental Therapeutics, dated March 3, 2016.

Neurotrope CSO to Participate in Alzheimer's Panel at 18th Annual BIO CEO & Investor Conference
GlobeNewswire - Thu Feb 04, 10:19AM CST
Neurotrope, Inc. (NTRP) today announced that its Chief Scientific Officer, Dr. Daniel Alkon, has been invited to present on a panel focused on new directions and progress of Alzheimer's disease research at the 18 Annual BIO CEO & Investor Conference, being held February 8-9, 2016 at the Waldorf Astoria Hotel in New York, New York.

Neurotrope Holds Investigators Meeting for U.S. Phase 2b Trial of Bryostatin-1 for Treatment of Alzheimer's Disease
GlobeNewswire - Wed Feb 03, 7:40AM CST
Neurotrope, Inc. (OTCBB:NTRP) today announced that it has held an Investigators Meeting in conjunction with its recently initiated Phase 2b trial for lead compound, Bryostatin-1 for the treatment of Alzheimer's disease. The meeting, held January 28-29, 2016 in Orlando, Florida, brought together more than 150 healthcare clinical professionals from 30 sites across the United States to discuss the goals for the study, in addition to providing the in-depth training necessary for the trial.

Neurotrope Initiates Phase 2b Study of Bryostatin for Treatment of Alzheimer's Disease
GlobeNewswire - Thu Jan 07, 7:30AM CST
Neurotrope, Inc. (OTCBB:NTRP) today announced the initiation of a Phase 2b clinical trial of lead candidate Bryostatin 1 for the treatment of Alzheimer's Disease.

Neurotrope, Inc. Announces $15.3 million Private Placement
PR Newswire - Mon Nov 16, 7:30AM CST
Neurotrope, Inc. (OTCQB: NTRP) today announced that it has entered into definitive agreements to sell its securities in a private placement. The securities purchase agreement provides for the sale of units to investors for $0.60 per unit with each unit consisting of one one-hundredth share of Series B Preferred Stock convertible into one share of common stock and one of each of the following warrants:

Neurotrope to Conduct Study on Niemann-Pick Type C, a Devastating Rare Pediatric Disease
PR Newswire - Wed Jun 24, 7:30AM CDT
Neurotrope, Inc. (OTCQB: NTRP) today announced that Neurotrope Bioscience, Inc., its operating wholly-owned subsidiary ("Neurotrope", will conduct a preclinical study, in collaboration with a leading research institution, to examine the effect of bryostatin in Niemann-Pick type C (NPC) mice. The study is being funded by several family foundations under the auspices of Support Of Accelerated Research for NPC Disease ("SOAR-NPC".

Neurotrope to Present Findings of In-vitro Studies of Bryostatin's Effects on Niemann Pick Type C1 Cells at the Annual "Michael, Marcia & Christa Parseghian Scientific Conference" for Niemann-Pick Type C
PR Newswire - Fri Jun 12, 7:30AM CDT
Neurotrope Bioscience, Inc. (Neurotrope or the Company), the operating subsidiary of Neurotrope, Inc. (OTCQB: NTRP) today announced the Company will present the findings of in vitro studies of bryostatin's effects on Niemann Pick Type C1 cells (NPC1 cells) at the annual "Michael, Marcia & Christa Parseghian Scientific Conference" for Niemann-Pick Type C research to be held on June 11 -13, 2015 at the University of Notre Dame. The Company's presentation will take place on Friday, June 12, at 2:30 pm Eastern time.

Neurotrope Joins National Organization for Rare Disorders (NORD) Corporate Council
PR Newswire - Thu Apr 23, 7:00AM CDT
Neurotrope, Inc. (OTCQB: NTRP) today announced that, based upon its work in orphan drug indications, it has been invited to join the National Organization for Rare Disorders (NORD) as a member of the NORD Corporate Council. NORD is a leading independent, non-profit organization committed to the identification, treatment, and cure of rare disorders.

Pharmacological Advancements in Neuroscience Drug Discovery & Pre-Clinical Studies for Fragile X Syndrome to Identify Drug Candidates for Autism Therapies Lead Biotech Sector Research
PR Newswire - Mon Apr 20, 7:35AM CDT
In the search for neuroscience drug discovery treatments, Alzheimer's disease and specifically autism drug candidates, a few viable therapeutic approaches have come from research on neurological conditions such as fragile X syndrome. Biotech Companies in focus today are Neurotrope, Inc. (OTC: NTRP), CytRx Corporation (NASDAQ: CYTR), Trovagene, Inc., (NASDAQ: TROV), Arena Pharmaceuticals, Inc. (NASDAQ: ARNA), Abbot Laboratories (NYSE: ABT) & Lexicon Pharmaceuticals, Inc. (NASDAQ: LXRX).
ABT: 39.44 (-0.10), LXRX: 14.45 (+0.04), TROV: 4.47 (-0.07), CYTR: 2.28 (+0.01), BMY: 73.78 (unch), ARNA: 1.60 (-0.06)

Neurotrope Receives Research Grant From the FRAXA Research Foundation to Fund Pre-Clinical Fragile X Syndrome Behavioral Studies
PR Newswire - Mon Apr 20, 6:55AM CDT
Neurotrope, Inc. (OTCQB: NTRP) today announced that eurotrope BioScience, Inc., its wholly-owned operating subsidiary, has received a grant from the FRAXA Research Foundation, Inc. ("FRAXA" to fund a pre-clinical Fragile X Syndrome ("FXS" behavior study for its lead proprietary drug candidate, bryostatin, at FRAXA's purpose built laboratory located at the University of Chile in Santiago, Chile.

Leading Biotech Companies Seek Biologic Treatments for Rare Diseases Utilizing Viable Therapeutic Approach - Company Receives FDA Orphan Drug Designation for Bryostatin
PR Newswire - Thu Apr 09, 7:35AM CDT
According to a recent article published on the Wall Street Journal, the debate over prescription drug pricing has grown increasingly contentious, particularly as drug makers issue more new medicines with high price tags. But despite the tumult, the cost for orphan drugs - medicines that are designated by the FDA to treat a rare disease and may cost as much as $400,000 annually - is apparently not fazing some insurers. Billions of dollars a year are being earmarked for new clinical studies and trials for the treatment of neurodevelopmental disorders as leading biotech companies race to identify treatments for genetic, cognitive, and neural levels for autism disorders. Biotech Companies in focus today are Neurotrope, Inc. (OTC: NTRP), Alkermes plc (NASDAQ: ALKS), Regulus Therapeutics Inc. (NASDAQ: RGLS), Inovio Pharmaceuticals, Inc. (NASDAQ: INO), Gilead Sciences Inc. (NASDAQ: GILD) and Abbot Laboratories (NYSE: ABT).
ABT: 39.44 (-0.10), INO: 9.17 (-0.18), GILD: 83.89 (-0.97), RGLS: 3.23 (+0.02), ALKS: 45.11 (-0.41)

Research & Clinical Trials for Prevention of Neurodegeneration Search for Viable Therapeutic Approach for the Treatment of Severe Alzheimer's Disease
PR Newswire - Mon Apr 06, 7:35AM CDT
The latest medical research and trials aimed to identify prevention of illnesses, particularly ones related to aging and lifestyle, including Alzheimer's disease, cancer, heart disease and other serious illnesses use innovative and novel approaches to ultimately develop the licensed technology for many types of cognitive dysfunctions. Biotech Companies in focus today: Neurotrope, Inc. (OTC: NTRP), Capnia, Inc. (NASDAQ: CAPN), Arena Pharmaceuticals, Inc., (NASDAQ: ARNA), Orexigen Therapeutics, Inc., (NASDAQ: OREX) & Inovio Pharmaceuticals, Inc., (NASDAQ: INO).
INO: 9.17 (-0.18), OREX: 0.43 (-0.02), CAPNU: (), ARNA: 1.60 (-0.06), CAPN: 1.18 (-0.01)

Neurotrope Selects Worldwide Clinical Trials to Commence Services for Phase 2B Trial of Bryostatin for the Treatment of Alzheimer's Disease
PR Newswire - Mon Apr 06, 7:00AM CDT
Neurotrope, Inc. (OTCQB: NTRP) today announced that Neurotrope Bioscience, Inc., its wholly-owned operating subsidiary, (the "Company" has selected Worldwide Clinical Trials (WCT) to commence the pre-patient enrollment activities for the conduct of a Phase 2b trial of the Company's compound bryostatin-1 for the treatment of Alzheimer's disease. WCT is a leading global clinical research organization with substantial experience in conducting trials in Alzheimer's disease.

Advances in Biotech Expanded Studies Lead to Cutting-Edge Therapeutic Treatments - Company Announces Positive Final Results in Treatment for Alzheimer's Disease
PR Newswire - Tue Mar 17, 7:35AM CDT
The latest medical projects aimed to prevent illnesses, particularly ones related to aging and lifestyle, including Alzheimer's disease, cancer, heart disease and other serious illnesses use innovative and novel approaches to ultimately develop the licensed technology for many types of cognitive dysfunctions. Biotech Companies in focus today: Neurotrope, Inc. (OTC: NTRP), TG Therapeutics, Inc. (NASDAQ: TGTX), Inovio Pharmaceuticals, Inc. (NASDAQ: INO), Lexicon Pharmaceuticals, Inc. (NASDAQ: LXRX) and Actavis plc (NYSE: ACT)
INO: 9.17 (-0.18), ACT: 298.98 (-2.94), LXRX: 14.45 (+0.04), TGTX: 6.00 (-0.37)

Scroll down for more posts ▼

Top 10 Most Recent News Articles

OCI N.V. Secures a Win in Court; EGM Proceeds as Planned

Updated Category News Views 19

OCI Dodges a Bullet in Amsterdam Court Stepping into the courtroom drama, OCI N.V. just took home a win as the Amsterdam Court of Appeal's Enterprise Chamber gave them a clean bill of health, kicking out the inquiry request from VEB and a bunch of other shareholders. The judges weren't convinced there was anything fishy going on, so they tossed the inquiry petition and...

Continue Reading
Wally Disrupts Dental Industry with $25M Funding

Updated Category News Views 22

A New Breath of Fresh Air for Dental Care Dental visits—a tedious, costly affair we've all dreaded. So, when Wally rolls out an overhaul in this stale landscape, it's worth taking notice. With $25 million in their pockets from Series A funding led by Maveron, Wally's swaggering in with a plan to flip the script on dental care across the nation. Redefining the Dental...

Continue Reading
U. of Phoenix and LACCD Launch 3+1 Degree Pathway

Updated Category News Views 9

Opening the Floodgates for Ambitious Community College Students When it comes to climbing the educational ladder, not everyone starts at the same rung. That's a fact we've all come to terms with in one way or another. Enter the University of Phoenix and the Los Angeles Community College District with a solution to expand educational access. The 3+1 Program: A Cost-Saving...

Continue Reading
Decoding CarBravo-Certified vs Traditional Used Cars

Updated Category News Views 14

What’s Behind Door Number One: CarBravo Certification When you walk onto a car lot these days, it's a mixed bag: shiny badges boasting certifications or basic used car signage. For anyone who's spent time around cars, two types stick out—there’s your CarBravo-certified vehicles and your good ol' used cars. Now, Marissa McCoy and Jill Maniaci from Heidebreicht...

Continue Reading
Duke Energy's Cost-Protection Plan Shields Ratepayers

Updated Category News Views 14

Shielding Customers From Data Center Costs Let's get right into the thick of it: Duke Energy's latest move is a strategic one, shrouded in industry terms but with a real impact on regular folks' wallets. The company's agreement with heavyweights like Amazon, Google, and Meta aims to protect existing customers in North Carolina from getting hit with the costs of powering...

Continue Reading
C3EL Expands Federal Footprint with Strategic Contracts

Updated Category News Views 5

Pushing Boundaries in Federal Contracts What a ride C3EL's had in Government Fiscal Year 2026! Let me tell you, they’ve bagged a bunch of contracts that’d make any company’s mouth water. Kicking things off, they snagged a prime cybersecurity contract from the U.S. Air Force. Considering our current cybersecurity landscape, that's like striking gold. But they...

Continue Reading
HelloNation Brings 'Edvertising' to NC REALTORS® Event

Updated Category News Views 19

HelloNation's Bold Step into Real Estate Networking October 8th to the 11th is shaping up to be a pivotal few days in Wilmington, North Carolina. Here’s the scoop: HelloNation, known for its innovative 'edvertising' model, is joining the bustling crowd at the 2026 NC REALTORS® Convention. This isn’t just any get-together—it's the grandest annual jamboree for real...

Continue Reading
EMCO's New Automated Facility Could Shake Industry

Updated Category News Views 14

A Novel Leap in Production Capacity EMCO Industries just put a solid foot on the accelerator with their brand-new, shiny, fully automated plant over in Claremore, Oklahoma. If you're glancing at heavy-duty trailer springs, you can't ignore the fact that this is a multimillion-dollar investment. Heck, this monstrous 30,000-square-foot facility more than doubles what EMCO...

Continue Reading
Gong, Agentforce, Avoma Crowned 2026 CI Champions

Updated Category News Views 16

Diving Deep into Conversation Intelligence There's a lot to unpack when three software titans hog the spotlight, and that's exactly what's happening in the world of conversation intelligence this year. It's like we've hit the jackpot with Gong, Agentforce Sales, and Avoma carving out their turf as the 2026 Champions, according to the venerable Info-Tech Research Group....

Continue Reading
Merit Expands in New York with Bold Acquisition Move

Updated Category News Views 15

Merit Financial's Growth Trajectory Takes a Leap You watch the movers and shakers in this game long enough, and you start to see patterns. Merit Financial Advisors is one of those juggernauts you'd better keep an eye on. These folks just scooped up Moldenhauer & Associates—a firm that's been a staple in Orchard Park, New York—for a cool $1.1 billion worth of client...

Continue Reading

Top 5 Most Recently Viewed Articles

ATI Reports Strong Q3 2024 Performance with Increased Sales

Updated Category News Views 38

ATI's Third Quarter Performance Overview ATI Inc. (NYSE: ATI) has recently reported its financial results for the third quarter of 2024, demonstrating its resilience with remarkable sales figures and strategic growth initiatives. Sales for this quarter reached an impressive $1.05 billion, marking the ninth consecutive quarter that sales have exceeded $1 billion. With a...

Continue Reading
Travel Trends for Thanksgiving: Americans Staying Home

Updated Category News Views 124

Shifting Thanksgiving Travel Trends This year, fewer Americans are gearing up for Thanksgiving travel, even as gas prices hover near years lows. Recent surveys highlight this shift in behavior, showcasing a changing mindset towards holiday travel amidst economic apprehensions. Gas Price Insights GasBuddy, a well-known fuel savings platform, forecasts a national average...

Continue Reading
Exploring Recent Options Trading Activities of Nu Holdings

Updated Category News Views 93

Recent Trends in Options Trading for Nu Holdings Nu Holdings has recently attracted attention from major financial players, who are displaying strong bullish inclinations. Our thorough analysis of options trading history for Nu Holdings (NYSE: NU) highlights the emergence of 9 unusual trades. This signifies an increased interest in this digital financial service provider....

Continue Reading
Travel Smart: Support Wildlife, Avoid Exploitation

Updated Category News Views 7

Rethink Wildlife Tourism for Ethical Travel You ever stopped to think about what those so-called wildlife attractions are really selling? It’s a feel-good illusion wrapped up in exploitation. Travelers often see animals as part of the backdrop of their holiday stories, but the reality is far from picturesque. Behind the photo ops, there's typically a grim story of...

Continue Reading
Analysts Revise AutoZone Price Targets After Soft Earnings

Updated Category News Views 188

Understanding AutoZone's Recent Earnings Report AutoZone, Inc. (NYSE: AZO) recently released its first-quarter earnings, and the results were below expectations. The Q1 earnings per share came in at $31.04, which was shy of the projected consensus estimate of $32.37. Furthermore, the reported quarterly sales were $4.629 billion, reflecting an 8.2% increase year-over-year,...

Continue Reading