It shows MIC values for PMX 30063 (Brilacidin) com
Post# of 72440
Posted On: 02/03/2016 10:48:52 AM
Re: thefamilyman #18214
It shows MIC values for PMX 30063 (Brilacidin) compared to Vancomycin. The lower the number the less of the drug necessary to kill the bacteria.
So the lower the number the better the antibiotic performed.
"In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of an antimicrobial that will inhibit the visible growth of a microorganism after overnight incubation. Minimum inhibitory concentrations are important in diagnostic laboratories to confirm resistance of microorganisms to an antimicrobial agent and also to determine the potency of new antimicrobial agents.[1] A MIC is generally regarded as the most basic laboratory measurement of the activity of an antimicrobial agent against an organism."
"Clinically, the minimum inhibitory concentrations are used not only to determine the amount of antibiotic that the patient will receive but also the type of antibiotic used, which in turn lowers the opportunity for microbial resistance to specific antimicrobial agents. Applying MIC testing to a number of bacterial strains in the same species provides an estimate of the concentration that inhibits 50% (MIC50) and 90% (MIC90) of bacterial isolates and can indicate shifts in the susceptibility of bacterial populations to antibiotics,[3] MICs are therefore often the starting point for larger preclinical evaluations of novel antimicrobial agents."
https://en.m.wikipedia.org/wiki/Minimum_inhib...centration
So the lower the number the better the antibiotic performed.
"In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of an antimicrobial that will inhibit the visible growth of a microorganism after overnight incubation. Minimum inhibitory concentrations are important in diagnostic laboratories to confirm resistance of microorganisms to an antimicrobial agent and also to determine the potency of new antimicrobial agents.[1] A MIC is generally regarded as the most basic laboratory measurement of the activity of an antimicrobial agent against an organism."
"Clinically, the minimum inhibitory concentrations are used not only to determine the amount of antibiotic that the patient will receive but also the type of antibiotic used, which in turn lowers the opportunity for microbial resistance to specific antimicrobial agents. Applying MIC testing to a number of bacterial strains in the same species provides an estimate of the concentration that inhibits 50% (MIC50) and 90% (MIC90) of bacterial isolates and can indicate shifts in the susceptibility of bacterial populations to antibiotics,[3] MICs are therefore often the starting point for larger preclinical evaluations of novel antimicrobial agents."
https://en.m.wikipedia.org/wiki/Minimum_inhib...centration
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