Yes sir! Because of the short t 1/2 (half-life), simply detecting P-21 can be tricky. The lab test may be done too far out from the dose administration and go undetected. But as you state a more frequent, or alternatively, a longer infusion would facilitate the detection. ***It wouldn't take long into phase II to see signs of efficacy.
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***On 02/26/2016 at 8:33 am Scottsmith admited to posting under 5 aliases but his post was subsequently deleted. I have a screen shot and will email it to anyone interested.