"A very good indication of the success of the prod

"A very good indication of the success of the prodrug approach can be obtained by examining the prevalence of prodrugs on the market. It might come as a surprise to many people that currently approximately 10% of all globally marketed medicines can be classified as prodrugs, and in 2008 alone, 33% of all approved small-molecular-weight drugs were prodrugs (Rautio, 2010; Stella, 2010). Despite these impressive numbers, we have only begun to appreciate the full potential of the prodrug approach in modern drug development, and many novel prodrug innovations await discovery. "

from your link

http://m.pharmrev.aspetjournals.org/content/63/3/750.full

Go Prurisol! Go CTIX!