SOUTH SAN FRANCISCO, Calif., Nov. 05, 2015 (GLOBE NEWSWIRE) -- Calithera Biosciences, Inc. (Nasdaq: CALA ), announced today that four abstracts highlighting the potential of CB-839, the Company’s novel, orally bioavailable glutaminase inhibitor for the treatment of hematological malignancies, have been selected for presentation at the 57 th American Society of Hematology (ASH) annual meeting and exposition, taking place December 5-8, 2015, in Orlando, Florida. Details for the presentations are as follows:
Metabolomic, Proteomic and Genomic Profiling Identifies Biomarkers of Sensitivity to Glutaminase Abstract #1802 Andrew L. MacKinnon, Ph.D., Calithera Biosciences Session Name: 652. Myeloma: Pathophysiology and Pre-Clinical Studies, excluding Therapy: Poster I Saturday, December 5, 2015 at 5:30-7:30 PM ET Orange County Convention Center, Hall A
Role of Glutamine in Metabolic and Epigenetic Reprogramming in AML Abstract #2559 Juliana Velez Lujan, Ph.D., University of Texas MD Anderson Cancer Center Session Name: 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster II Sunday, December 6, 2015 at 6:00-8:00 PM ET Orange County Convention Center, Hall A
Phase I Study of CB-839, a First-in-class, Orally Administered Small Molecule Inhibitor of Glutaminase in Patients With Relapsed/ Refractory Leukemia Abstract #2566 Eunice S. Wang, M.D., Roswell Park Cancer Institute Session Name: 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster II Sunday, December 6, 2015 at 6:00-8:00 PM ET Orange County Convention Center, Hall A
Phase I Study of CB-839, a First-in-class, Glutaminase Inhibitor in Patients With Multiple Myeloma and Lymphoma Abstract #3059 Dan Vogl, M.D., University of Pennsylvania Session Name: 653. Myeloma: Therapy, excluding Transplantation: Poster II Sunday, December 6, 2015 at 6:00-8:00 PM ET Orange County Convention Center, Hall A
The meeting abstracts can be viewed online through the ASH website at www.hematology.org .
About Calithera Biosciences
Calithera Biosciences is a clinical-stage company focused on discovering and developing novel small molecule drugs directed against tumor metabolism and tumor immunology. Calithera's lead clinical candidate, CB-839, is a first-in-class inhibitor of glutaminase, a critical enzyme in tumor metabolism, and is currently being tested in patients with solid and hematological cancers. CB-1158 is a first-in-class immuno-oncology metabolic checkpoint inhibitor targeting arginase, a critical immunosuppressive enzyme responsible for T-cell suppression by myeloid-derived suppressor cells. Arginase depletes arginine, a nutrient that is critical for the activation, growth and survival of the body’s cancer-fighting immune cells, known as cytotoxic T-cells. Calithera Biosciences is headquartered in South San Francisco. For more information about Calithera Biosciences, please visit www.calithera.com .
CONTACT: Jennifer McNealey ir@Calithera.com 650-870-1071