Portage Biotech Inc (PTGEF) 0.2300 $PTGEF
Portage's Biohaven's lead drug candidate clears FDA Investigational New Drug Application (IND) review and clinical studies to begin
PR Newswire - Mon Aug 24, 8:00AM CDT
Portage Biotech Inc. ("Portage"
(OTC Market: PTGEF, Canadian Securities Exchange: PBT.U) and Biohaven Pharmaceutical Holding Company Limited ("Biohaven" are pleased to announce that the United States Food and Drug Administration has completed its review of Biohaven's Investigational New Drug Application (IND) for BHV-0223 and initial clinical studies in humans may begin. Portage holds 54% equity interest in Biohaven.
Portage's Biohaven Acquires Intellectual Property for Portfolio of Prodrugs from ALS Biopharma, LLC
PR Newswire - Tue Aug 18, 8:00AM CDT
Portage Biotech Inc. ("Portage" (OTC Market: PTGEF, Canadian Securities Exchange: PBT.U) and Biohaven Pharmaceutical Holding Company Limited ("Biohaven" are pleased to announce that Biohaven has acquired the world-wide intellectual property rights to a portfolio of over 300 prodrugs owned by ALS Biopharma, LLC ("ALSBio". The prodrugs covered by the agreement were designed and prepared by Fox Chase Chemical Diversity Center, Inc. ("FCCDC" through a research program funded, in part, by the U.S. National Institutes of Health, through two peer-reviewed Small Business Innovation Research (SBIR) grants awarded to FCCDC. Most of the ALSBio prodrugs would be classified as New Molecular Entities (NMEs), and the intellectual property rights acquired by Biohaven include all future therapeutic indications.
Portage's Biohaven raises $ 4.1 million in first tranche of private placement. Portage invests $ 2.5 million
PR Newswire - Tue Aug 11, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U) is pleased to announce that Biohaven Pharmaceutical Holding Company Limited (Biohaven), in which Portage holds 54% equity, has raised approximately $4.1 million by closing the first tranche of the non-brokered Private Placement. Pursuant to the terms of the private placement, Biohaven issued 1,464 common shares at a price of US$2,800 per share. Portage invested $ 2.5 million in the Biohaven placement.
Portage Invests in Sentien Biotechnologies Inc.
PR Newswire - Mon Aug 10, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (Canadian Securities Exchange: PBT.U, OTC Markets : PTGEF), is pleased to announce that it has made a Series A investment in Sentien Biotechnologies Inc.("Sentien", a Medford, MA based regenerative medicine company. Portage is joined in this round of investment by Boehringer Ingelheim Venture Fund USA, Inc. ("BIVF". Sentien will use the proceeds of its Series A round to fund its activities through a planned Phase I study of their lead product, the Sentinel(TM), a cell-containing dialysis device for the treatment of Acute Kidney Injury (AKI).
Portage's Biohaven Announces IND Filing for BHV-0223 for Phase 1 Clinical Testing
PR Newswire - Thu Jul 23, 8:00AM CDT
Portage Biotech Inc. ("Portage" (OTC Market: PTGEF, Canadian Securities Exchange: PBT.U), and Biohaven Pharmaceutical Holding Company Limited (Biohaven), are pleased to announce that Biohaven has filed an Investigational New Drug (IND) Application with the U.S. Food and Drug Administration (FDA) to conduct clinical testing of BHV-0223. Portage holds 54% equity interest in Biohaven, a private company.
Portage Completes Non-brokered Private Placement in Two Tranches for a Total Proceeds of US$ 5,155,080
PR Newswire - Thu Jun 25, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (Canadian Securities Exchange: PBT.U , OTC Markets : PTGEF,), is pleased to announce that it has completed its non-brokered private placement raising US$5,155,080 through issuance of approximately 36.8 million common shares at US$0.14 each. The private placement was completed in two tranches, first tranche closed on June 15, 2015 as per our press release of June 16, 2015 and second and final tranche closed on June 24, 2015. The Company is debt free. Total number of common shares issued and outstanding after this private placement are 245,438,890.
Portage Closes First Tranche of Private Placement
PR Newswire - Tue Jun 16, 3:52PM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), announces that it has raised approximately $3.4 million by closing the first tranche of the non-brokered Private Placement previously announced on May 19, 2015. Pursuant to the terms of the private placement, Portage issued 23,881,214 common shares at a price of US$0.14 per share. All shares issued under private placement are subject to statutory hold periods. Two of the directors of the Company, Dr. Bailey and Mr. Mellon subscribed US$ 800,000 each.
Portage Biotech Announces Non-Brokered Private Placement - Video News Alert on InvestmentPitch.com
Newsfile Corp - Thu May 21, 10:08AM CDT
full story)
Portage announces proposed Private Placement
PR Newswire - Tue May 19, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), announces that it intends to conduct a Private Placement to raise up to US$ 5 million for funding its development activities, plan new acquisitions to expand its pipeline and finance clinical activities at Biohaven Pharmaceutical Holding Company Limited, ("Biohaven".
Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016
PR Newswire - Wed Apr 22, 10:00AM CDT
Biohaven to Initiate Pharmacokinetic and Biomarker Study with Lead Drug Development Candidate in 3Q2015
Portage's CPP Platform Delivers a Peptide Cargo Across Blood Brain Barrier
PR Newswire - Mon Apr 20, 7:48AM CDT
Portage Pharmaceuticals Ltd. (PPL) Announces that its Proprietary Human-Derived Cell Permeable Peptide (CPP) Platform Delivers a Peptide Cargo Across the Blood Brain Barrier and that this Construct Demonstrates CNS Activity.
Portage to Present at Master Investor 2015 in London, UK
PR Newswire - Thu Apr 16, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" )) (OTC Market: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that the Company will be presenting at the Master Investor Show on April 25, 2015 to be held in London, UK. Portage's chairman, Dr. Gregory Bailey and Mr. James Mellon, a director of Portage, will provide an overview and an update on the key programs at its subsidiaries, Portage Pharmaceuticals Ltd. ("PPL", and Biohaven Pharmaceuticals Holding Company Ltd. ("Biohaven", wherein the Company holds 54% equity. The Company's presentation materials will be available at the Portage booth at the Show.
CTLT: 28.33 (+0.15)
Portage's Biohaven Announces Agreement with inVentiv Health
PR Newswire - Wed Apr 01, 8:00AM CDT
Biohaven and inVentiv Health Enter into Agreement for Operational Execution of Biohaven's Lead Compound Phase 1 Clinical Trial.
Portage's Biohaven enters into exclusive formulation agreement and global license with Catalent for lead product
PR Newswire - Tue Mar 24, 8:00AM CDT
Catalent has completed prototype formulation development and is delivering drug supplies for Biohaven's lead clinical product.
CTLT: 28.33 (+0.15)
Portage's Biohaven Receives Response from FDA to its Pre-IND Meeting Request
PR Newswire - Thu Dec 18, 8:00AM CST
Biohaven filed a pre-IND meeting request with the FDA regarding lead investigational agent BHV-0223, receives written response in lieu of an in-person meeting
Portage announces further successful validation of its new proprietory cell permeable peptide platform technology
PR Newswire - Tue Dec 16, 8:00AM CST
Portage Biotech Inc. ("Portage" (OTCQB: PTGEF, Canadian Stock Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary Portage Pharmaceuticals Ltd. (PPL) has further validated its platform cell penetrating peptide technology for safely delivering a potent anti-inflammatory cargo into eye tissues. Its lead compound PPL-003 showed success in two studies in rabbits. In the first study, topical eye administration of PPL-003 at the highest feasible dose was well tolerated with no abnormal clinical or pathological findings. In the second study PPL-003 demonstrated efficacy in an experimental uveitis model by significantly suppressing the cellular inflammatory response in the anterior chamber and reducing the protein content of the anterior chamber aqueous humor.. These results in rabbits clearly demonstrated at least a ten-fold safety margin and confirmed the topical anti-inflammatory activity of PPL-003 previously demonstrated in a mouse uveitis model. PPL is continuing its uveitis program working toward an IND submission in 2016.
Portage Completes Non-brokered Private Placement for a Total Proceeds of US$2,000,000
PR Newswire - Thu Oct 16, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that it has completed its non-brokered private placement raising US$2,000,000 through issuance of 20 million common shares at US$0.10 each. The Company is debt free.
Portage announces additional consultants to expedite its PPL-003 development programs
PR Newswire - Mon Oct 06, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary, Portage Pharmaceuticals Ltd (PPL) has added the following consultants to its team for further development of its PPL-003 for uveitis and planning for its potential Investigational New Drug (IND) application with FDA. PPL-003 uses a new proprietary cell permeable peptide platform technology derived from human genes to deliver its anti-inflammatory cargo into the eye.
Portage announces conversion of its debt into equity
PR Newswire - Mon Sep 29, 1:11PM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its three Promissory Note holders, two of whom are the directors of Portage, who advanced $ 100,000 each in July 2014 for a total of $ 300,000 opted to have their Notes and related Coupons converted into 3,500,001 restricted common shares. Notes were repayable within one year and carried 5% coupon. Both the Note and the coupon were convertible into common shares to be valued at 10% discount to the current financing at $ 0.10 per share.
Portage Announces New Consultants for its PPL-003 Development Programs
PR Newswire - Tue Sep 23, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" (OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary, Portage Pharmaceuticals Ltd (PPL) has added two more consultants to its team for further development of its PPL-003 for uveitis. PPL-003 uses a new proprietary cell permeable peptide platform technology derived from human genes to deliver its anti-inflammatory cargo into the eye.
Portage's Biohaven's lead drug candidate clears FDA Investigational New Drug Application (IND) review and clinical studies to begin
PR Newswire - Mon Aug 24, 8:00AM CDT
Portage Biotech Inc. ("Portage"
(OTC Market: PTGEF, Canadian Securities Exchange: PBT.U) and Biohaven Pharmaceutical Holding Company Limited ("Biohaven" are pleased to announce that the United States Food and Drug Administration has completed its review of Biohaven's Investigational New Drug Application (IND) for BHV-0223 and initial clinical studies in humans may begin. Portage holds 54% equity interest in Biohaven. Portage's Biohaven Acquires Intellectual Property for Portfolio of Prodrugs from ALS Biopharma, LLC
PR Newswire - Tue Aug 18, 8:00AM CDT
Portage Biotech Inc. ("Portage"
(OTC Market: PTGEF, Canadian Securities Exchange: PBT.U) and Biohaven Pharmaceutical Holding Company Limited ("Biohaven" are pleased to announce that Biohaven has acquired the world-wide intellectual property rights to a portfolio of over 300 prodrugs owned by ALS Biopharma, LLC ("ALSBio". The prodrugs covered by the agreement were designed and prepared by Fox Chase Chemical Diversity Center, Inc. ("FCCDC" through a research program funded, in part, by the U.S. National Institutes of Health, through two peer-reviewed Small Business Innovation Research (SBIR) grants awarded to FCCDC. Most of the ALSBio prodrugs would be classified as New Molecular Entities (NMEs), and the intellectual property rights acquired by Biohaven include all future therapeutic indications. Portage's Biohaven raises $ 4.1 million in first tranche of private placement. Portage invests $ 2.5 million
PR Newswire - Tue Aug 11, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U) is pleased to announce that Biohaven Pharmaceutical Holding Company Limited (Biohaven), in which Portage holds 54% equity, has raised approximately $4.1 million by closing the first tranche of the non-brokered Private Placement. Pursuant to the terms of the private placement, Biohaven issued 1,464 common shares at a price of US$2,800 per share. Portage invested $ 2.5 million in the Biohaven placement. Portage Invests in Sentien Biotechnologies Inc.
PR Newswire - Mon Aug 10, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(Canadian Securities Exchange: PBT.U, OTC Markets : PTGEF), is pleased to announce that it has made a Series A investment in Sentien Biotechnologies Inc.("Sentien", a Medford, MA based regenerative medicine company. Portage is joined in this round of investment by Boehringer Ingelheim Venture Fund USA, Inc. ("BIVF". Sentien will use the proceeds of its Series A round to fund its activities through a planned Phase I study of their lead product, the Sentinel(TM), a cell-containing dialysis device for the treatment of Acute Kidney Injury (AKI). Portage's Biohaven Announces IND Filing for BHV-0223 for Phase 1 Clinical Testing
PR Newswire - Thu Jul 23, 8:00AM CDT
Portage Biotech Inc. ("Portage"
(OTC Market: PTGEF, Canadian Securities Exchange: PBT.U), and Biohaven Pharmaceutical Holding Company Limited (Biohaven), are pleased to announce that Biohaven has filed an Investigational New Drug (IND) Application with the U.S. Food and Drug Administration (FDA) to conduct clinical testing of BHV-0223. Portage holds 54% equity interest in Biohaven, a private company. Portage Completes Non-brokered Private Placement in Two Tranches for a Total Proceeds of US$ 5,155,080
PR Newswire - Thu Jun 25, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(Canadian Securities Exchange: PBT.U , OTC Markets : PTGEF,), is pleased to announce that it has completed its non-brokered private placement raising US$5,155,080 through issuance of approximately 36.8 million common shares at US$0.14 each. The private placement was completed in two tranches, first tranche closed on June 15, 2015 as per our press release of June 16, 2015 and second and final tranche closed on June 24, 2015. The Company is debt free. Total number of common shares issued and outstanding after this private placement are 245,438,890. Portage Closes First Tranche of Private Placement
PR Newswire - Tue Jun 16, 3:52PM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), announces that it has raised approximately $3.4 million by closing the first tranche of the non-brokered Private Placement previously announced on May 19, 2015. Pursuant to the terms of the private placement, Portage issued 23,881,214 common shares at a price of US$0.14 per share. All shares issued under private placement are subject to statutory hold periods. Two of the directors of the Company, Dr. Bailey and Mr. Mellon subscribed US$ 800,000 each. Portage Biotech Announces Non-Brokered Private Placement - Video News Alert on InvestmentPitch.com
Newsfile Corp - Thu May 21, 10:08AM CDT
full story)
Portage announces proposed Private Placement
PR Newswire - Tue May 19, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), announces that it intends to conduct a Private Placement to raise up to US$ 5 million for funding its development activities, plan new acquisitions to expand its pipeline and finance clinical activities at Biohaven Pharmaceutical Holding Company Limited, ("Biohaven". Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016
PR Newswire - Wed Apr 22, 10:00AM CDT
Biohaven to Initiate Pharmacokinetic and Biomarker Study with Lead Drug Development Candidate in 3Q2015
Portage's CPP Platform Delivers a Peptide Cargo Across Blood Brain Barrier
PR Newswire - Mon Apr 20, 7:48AM CDT
Portage Pharmaceuticals Ltd. (PPL) Announces that its Proprietary Human-Derived Cell Permeable Peptide (CPP) Platform Delivers a Peptide Cargo Across the Blood Brain Barrier and that this Construct Demonstrates CNS Activity.
Portage to Present at Master Investor 2015 in London, UK
PR Newswire - Thu Apr 16, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company" )) (OTC Market: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that the Company will be presenting at the Master Investor Show on April 25, 2015 to be held in London, UK. Portage's chairman, Dr. Gregory Bailey and Mr. James Mellon, a director of Portage, will provide an overview and an update on the key programs at its subsidiaries, Portage Pharmaceuticals Ltd. ("PPL"
, and Biohaven Pharmaceuticals Holding Company Ltd. ("Biohaven", wherein the Company holds 54% equity. The Company's presentation materials will be available at the Portage booth at the Show. CTLT: 28.33 (+0.15)
Portage's Biohaven Announces Agreement with inVentiv Health
PR Newswire - Wed Apr 01, 8:00AM CDT
Biohaven and inVentiv Health Enter into Agreement for Operational Execution of Biohaven's Lead Compound Phase 1 Clinical Trial.
Portage's Biohaven enters into exclusive formulation agreement and global license with Catalent for lead product
PR Newswire - Tue Mar 24, 8:00AM CDT
Catalent has completed prototype formulation development and is delivering drug supplies for Biohaven's lead clinical product.
CTLT: 28.33 (+0.15)
Portage's Biohaven Receives Response from FDA to its Pre-IND Meeting Request
PR Newswire - Thu Dec 18, 8:00AM CST
Biohaven filed a pre-IND meeting request with the FDA regarding lead investigational agent BHV-0223, receives written response in lieu of an in-person meeting
Portage announces further successful validation of its new proprietory cell permeable peptide platform technology
PR Newswire - Tue Dec 16, 8:00AM CST
Portage Biotech Inc. ("Portage"
(OTCQB: PTGEF, Canadian Stock Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary Portage Pharmaceuticals Ltd. (PPL) has further validated its platform cell penetrating peptide technology for safely delivering a potent anti-inflammatory cargo into eye tissues. Its lead compound PPL-003 showed success in two studies in rabbits. In the first study, topical eye administration of PPL-003 at the highest feasible dose was well tolerated with no abnormal clinical or pathological findings. In the second study PPL-003 demonstrated efficacy in an experimental uveitis model by significantly suppressing the cellular inflammatory response in the anterior chamber and reducing the protein content of the anterior chamber aqueous humor.. These results in rabbits clearly demonstrated at least a ten-fold safety margin and confirmed the topical anti-inflammatory activity of PPL-003 previously demonstrated in a mouse uveitis model. PPL is continuing its uveitis program working toward an IND submission in 2016. Portage Completes Non-brokered Private Placement for a Total Proceeds of US$2,000,000
PR Newswire - Thu Oct 16, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that it has completed its non-brokered private placement raising US$2,000,000 through issuance of 20 million common shares at US$0.10 each. The Company is debt free. Portage announces additional consultants to expedite its PPL-003 development programs
PR Newswire - Mon Oct 06, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary, Portage Pharmaceuticals Ltd (PPL) has added the following consultants to its team for further development of its PPL-003 for uveitis and planning for its potential Investigational New Drug (IND) application with FDA. PPL-003 uses a new proprietary cell permeable peptide platform technology derived from human genes to deliver its anti-inflammatory cargo into the eye. Portage announces conversion of its debt into equity
PR Newswire - Mon Sep 29, 1:11PM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its three Promissory Note holders, two of whom are the directors of Portage, who advanced $ 100,000 each in July 2014 for a total of $ 300,000 opted to have their Notes and related Coupons converted into 3,500,001 restricted common shares. Notes were repayable within one year and carried 5% coupon. Both the Note and the coupon were convertible into common shares to be valued at 10% discount to the current financing at $ 0.10 per share. Portage Announces New Consultants for its PPL-003 Development Programs
PR Newswire - Tue Sep 23, 8:00AM CDT
Portage Biotech Inc. ("Portage" or "the Company"
(OTC: PTGEF, Canadian Securities Exchange: PBT.U), is pleased to announce that its wholly owned subsidiary, Portage Pharmaceuticals Ltd (PPL) has added two more consultants to its team for further development of its PPL-003 for uveitis. PPL-003 uses a new proprietary cell permeable peptide platform technology derived from human genes to deliver its anti-inflammatory cargo into the eye. 
