Onconova (ONTX) Soars on FDA Submission for HR-MDS Drug

New Post Public Reply Private Reply Replies (0) Message Board
riddock57
The price of the stock of Nordstrom Inc. (JWN) surged more than 5% in after-hours trading Thursday as the company delivered quarterly profit numbers above Wall Street analysts' expectations

For its second quarter 2015, JWN posted net sales of $3.6 billion, a 9.2% increase year over year, and earnings per diluted share of $0.93 per share (excluding $0.16 gain from the reclassification of receivables as "held for sale" associated with the pending credit card transaction), topping the Capital IQ Consensus Estimate of $0.90 earnings per share for the period

On May 26, 2015, JWN announced its strategic credit card relationship with TD Bank, including the sale of its existing U.S. Visa and private label consumer credit card portfolio. JWN also entered into a program agreement with TD Bank, in which it will be entitled to a substantial portion of net revenue generated by the credit card portfolio.

Upon closing, JWN expects to receive approximately $1.8 billion, net of $325 million in debt reduction and transaction costs. In the second quarter, JWN reclassified its receivables to "held for sale" resulting in the reduction of expense.

JWN has raised its guidance for fiscal year 2015 and now expects net sales growth to be in the range of 8.5% to 9.5% (from the prior range of 7% to 9%) and Earnings per diluted share (excluding non-recurring items) to be in the range of $3.70 to $3.80 (from the previous range of $3.65 to $3.80)

JWN is a leading fashion specialty retailer based in the U.S.

More about Nordstrom Inc. (JWN) at www.nordstrom.com

**

Shares of Onconova Therapeutics, Inc. (ONTX) soared over 25% during the extended session Thursday after the company announced the submission of an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) for IV rigosertib as a treatment for higher-risk myelodysplastic syndromes (HR-MDS) after failure of hypomethylating agent (HMA) therapy, which positions ONTX's rigosertib back on an approval track in HR-MDS.

ONTX's rigosertib is a small molecule that inhibits cellular signaling by acting as a Ras mimetic. This is believed to be mediated by direct binding of rigosertib to the Ras-binding domain found in many Ras effector proteins, including the Raf kinases and PI3K. The initial therapeutic focus for rigosertib is myelodysplastic syndromes (MDS), a group of bone marrow disorders characterized by ineffective formation of blood cells that often converts into acute myeloid leukemia

Upon clearance, the IND enables ONTX to initiate a randomized, controlled pivotal Phase 3 trial in patients with HR-MDS that have failed prior HMA therapy. ONTX also said that it plans to submit Clinical Trial Applications in several European countries shortly and the company anticipates initiating enrollment in the new Phase 3 study in the second half of 2015.

ONTX is a clinical-stage biopharmaceutical company focused on discovering and developing novel products to treat cancer.

More about Onconova Therapeutics, Inc. (ONTX) at www.onconova.com

**

Crown Equity Holdings Inc. (CRWE) is currently developing its CRWE WORLD ( www.crweworld.com ), a community targeted platform which goal is to be a one-stop shop for the various needs of online consumers in a range of marketing specialties like Real Estate, Coupons & Deals, Business Directory and more

CRWE WORLD’s business model is based on selling advertising to businesses targeting their marketing message locally, nationally, internationally and also to target potential clients for an specific location, such as within a certain zip code.

The company’s CRWE Press Release ( www.crwepressrelease.com ) offers increased visibility with cost effective solutions through the distribution of information to the entire CRWE WORLD Network for both public and private companies.

CRWE provides marketing solutions that boost customer awareness and merchant visibility on the Internet.

More about Crown Equity Holdings Inc. (CRWE) at www.crownequityholdings.com

**

Disclaimer: The disclaimer is to be read and fully understood before using our site, or joining our email list. CRWE PR Finance is not a registered investment adviser. This material is for informational purposes only and should not be construed as an offer or solicitation of an offer to buy or sell securities. Investors should always conduct their own due diligence with any potential investment, with independent research and other professional advice. Read Full Disclaimer at CRWE PR Finance www.finance.crwe-pr.com/disclaimer

Traws Pharma Inc. (TRAW) Stock Research Links

TRAW Board Company Profile Buy Rating Time & Sales News Filings Financials
Scroll down for more posts ▼

Top 10 Most Recent News Articles

Top 5 Most Recently Viewed Articles

Historic Unity Among U.S. Latino Leaders for Mexico's Inauguration

Updated Category News Views 171

U.S. Latino leaders gathered for a historic delegation to Mexico, coinciding with the inauguration of Dra. Claudia Sheinbaum Pardo as Mexico's first female president back in 2024. This was no ordinary trip; it was a strategic move to tighten bonds between the two nations at a pivotal moment, hoping to reshape how Mexican-Americans influenced U.S. policy. Binational Ties:...

Continue Reading
Forecast for Structural Heart Devices Market Growth to USD 25B

Updated Category News Views 171

The Future of Structural Heart Devices Market Growth The structural heart devices market is on an impressive growth trajectory, projected to reach approximately USD 25 billion within the coming years. This expansion is primarily driven by the escalating demand for innovative solutions to manage various structural heart conditions. Understanding Structural Heart Devices...

Continue Reading
MediPharm Labs' Co-Founder Transitions to Board Role

Updated Category News Views 49

Significant Changes at MediPharm Labs MediPharm Labs Corp. (TSX: LABS, OTCQX: MEDIF), a leader in pharmaceutical-quality cannabis extraction and hemp-based products, has announced the departure of its President and Co-Founder, Keith Strachan, from his management role. Effective immediately, Keith will transition to the Board of Directors, where his strategic input will...

Continue Reading
Interactive Brokers Delivers Strong Performance in Q3 2024

Updated Category News Views 280

Interactive Brokers Group Reports Strong Financial Growth Interactive Brokers Group (NASDAQ: IBKR) has announced impressive financial results for the third quarter of 2024, capitalizing on a beneficent market following a U.S. interest rate cut. The company experienced significant year-over-year growth across key metrics such as client accounts, equity, and revenue....

Continue Reading
Publicis Groupe's Share Trading Update and Future Prospects

Updated Category News Views 198

Overview of Recent Share Trading Activities Publicis Groupe has recently engaged in trading its own shares as part of a program approved during its Shareholders’ Meetings. This initiative underscores the company's commitment to managing its share capital effectively, reflecting its ongoing strategy to enhance shareholder value. Transaction Details During the designated...

Continue Reading