Prothena Corporation plc (PRTA) said that results from a Phase 1 single ascending dose study showed that administration of PRX002, a monoclonal antibody for the potential treatment of Parkinson's disease and other related synucleinopathies, leads to mean reduction of free serum alpha-synuclein levels of up to 96% and demonstrates the pharmacodynamic effects of PRX002.
Alpha-synuclein is a protein found in neurons and is a major component of pathology that characterizes several neurodegenerative disorders including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, which collectively are termed synucleinopathies.
PRX002, the focus of a worldwide collaboration between PRTA and Roche, was safe and well-tolerated, meeting the primary objective of the study.
According to PRTA, this approach may translate into a clinically meaningful delay or reversal of disease progression in patients with Parkinson's disease, a degenerative disorder of the central nervous system that causes tremors, muscle stiffness, slowness of movement, and poor balance and mobility, affecting one in 100 people over age 60.
Shares of PRTA soared more than 40% Thursday in extended-hours trading following the company's announcement.
PRTA is a late-stage clinical biotechnology company focused on the discovery, development and commercialization of novel protein immunotherapy programs for the potential treatment of diseases that involve amyloid or cell adhesion.
More about Prothena Corporation plc (PRTA) at www.prothena.com.
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After the closing bell on Thursday, Envivio, Inc. (ENVI) delivered improved quarterly financial results with a reduction in its losses.
For its fourth quarter fiscal 2015, ENVI posted revenue of $12.73 million, up 42% sequentially and 1.94% year over year, while its non-GAAP net loss improved to ($0.5) million, or ($0.02) per share, from a non-GAAP net loss of ($4.1) million, or ($0.15) per share in the previous quarter and a non-GAAP net loss of ($1.4) million, or ($0.05) per share in the same period the prior year
ENVI is a global market leader and innovator of video software solutions that are trusted by video service providers and content companies worldwide to power stunning video quality and captivating, personalized experiences to their millions of viewers on any device, over any network.
More about Envivio, Inc. (ENVI) at www.envivio.com
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The price of Nike, Inc. (NKE) stock touched a new 52-week high in after-hours trading on Thursday, following the release of its quarterly earnings report with profit numbers above analysts’ expectations
For its third quarter fiscal 2015, NKE posted revenues of $7.5 billion, a 7% increase year over year, and net income of $791 million, or $0.89 per diluted share, compared to net income of $682 million, or $0.75 per diluted share in the same quarter the prior year, exceeding the Capital IQ Consensus Estimate of $0.84 earnings per share for the period
NKE is the world’s leading designer, marketer and distributor of authentic athletic footwear, apparel, equipment and accessories for a wide variety of sports and fitness activities.
More about Nike, Inc. (NKE) at www.nikeinc.com
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Crown Equity Holdings Inc. (CRWE) is currently developing its CRWE Network ( www.CRWE-PR.com ), a growing network of community targeted sites.
It has recently included the City of Citrus Heights, CA ( www.citrusheights.crwe-pr.com ) into the CRWE Network.
Citrus Heights is located in Sacramento County, California, and situated between downtown Sacramento and Roseville. It is home to a bustling retail and service industry.
The City of Citrus Heights had an estimated population in 2013 (U.S. Census Bureau) of 85,285, and represents an important marketplace for the CRWE Network, which business model is based on selling advertising to businesses targeting both locally and nationally
The CRWE Network has reached the 1487th community website in the U.S. and includes coverage in the states of California, Mississippi, Michigan, Florida, Nevada and New York, as well as across 10 provinces in Canada.
CRWE provides marketing solutions that boost customer awareness and merchant visibility on the Internet.
More about Crown Equity Holdings Inc. (CRWE) at www.crownequityholdings.com
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Disclaimer: CRWE-PR Finance is not a registered investment adviser. This material is for informational purposes only and should not be construed as an offer or solicitation of an offer to buy or sell securities. Investors should always conduct their own due diligence with any potential investment, with independent research and other professional advice. Read Full Disclaimer at CRWE-PR Finance www.finance.crwe-pr.com/disclaimer
Alpha-synuclein is a protein found in neurons and is a major component of pathology that characterizes several neurodegenerative disorders including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, which collectively are termed synucleinopathies.
PRX002, the focus of a worldwide collaboration between PRTA and Roche, was safe and well-tolerated, meeting the primary objective of the study.
According to PRTA, this approach may translate into a clinically meaningful delay or reversal of disease progression in patients with Parkinson's disease, a degenerative disorder of the central nervous system that causes tremors, muscle stiffness, slowness of movement, and poor balance and mobility, affecting one in 100 people over age 60.
Shares of PRTA soared more than 40% Thursday in extended-hours trading following the company's announcement.
PRTA is a late-stage clinical biotechnology company focused on the discovery, development and commercialization of novel protein immunotherapy programs for the potential treatment of diseases that involve amyloid or cell adhesion.
More about Prothena Corporation plc (PRTA) at www.prothena.com.
**
After the closing bell on Thursday, Envivio, Inc. (ENVI) delivered improved quarterly financial results with a reduction in its losses.
For its fourth quarter fiscal 2015, ENVI posted revenue of $12.73 million, up 42% sequentially and 1.94% year over year, while its non-GAAP net loss improved to ($0.5) million, or ($0.02) per share, from a non-GAAP net loss of ($4.1) million, or ($0.15) per share in the previous quarter and a non-GAAP net loss of ($1.4) million, or ($0.05) per share in the same period the prior year
ENVI is a global market leader and innovator of video software solutions that are trusted by video service providers and content companies worldwide to power stunning video quality and captivating, personalized experiences to their millions of viewers on any device, over any network.
More about Envivio, Inc. (ENVI) at www.envivio.com
**
The price of Nike, Inc. (NKE) stock touched a new 52-week high in after-hours trading on Thursday, following the release of its quarterly earnings report with profit numbers above analysts’ expectations
For its third quarter fiscal 2015, NKE posted revenues of $7.5 billion, a 7% increase year over year, and net income of $791 million, or $0.89 per diluted share, compared to net income of $682 million, or $0.75 per diluted share in the same quarter the prior year, exceeding the Capital IQ Consensus Estimate of $0.84 earnings per share for the period
NKE is the world’s leading designer, marketer and distributor of authentic athletic footwear, apparel, equipment and accessories for a wide variety of sports and fitness activities.
More about Nike, Inc. (NKE) at www.nikeinc.com
**
Crown Equity Holdings Inc. (CRWE) is currently developing its CRWE Network ( www.CRWE-PR.com ), a growing network of community targeted sites.
It has recently included the City of Citrus Heights, CA ( www.citrusheights.crwe-pr.com ) into the CRWE Network.
Citrus Heights is located in Sacramento County, California, and situated between downtown Sacramento and Roseville. It is home to a bustling retail and service industry.
The City of Citrus Heights had an estimated population in 2013 (U.S. Census Bureau) of 85,285, and represents an important marketplace for the CRWE Network, which business model is based on selling advertising to businesses targeting both locally and nationally
The CRWE Network has reached the 1487th community website in the U.S. and includes coverage in the states of California, Mississippi, Michigan, Florida, Nevada and New York, as well as across 10 provinces in Canada.
CRWE provides marketing solutions that boost customer awareness and merchant visibility on the Internet.
More about Crown Equity Holdings Inc. (CRWE) at www.crownequityholdings.com
**
Disclaimer: CRWE-PR Finance is not a registered investment adviser. This material is for informational purposes only and should not be construed as an offer or solicitation of an offer to buy or sell securities. Investors should always conduct their own due diligence with any potential investment, with independent research and other professional advice. Read Full Disclaimer at CRWE-PR Finance www.finance.crwe-pr.com/disclaimer
