Cannabidiol as a potential treatment for psychosis
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Posted On: 03/05/2015 12:24:57 PM
Cannabidiol as a potential treatment for psychosis.
Eur Neuropsychopharmacol. 2014 Jan;24(1):51-64. doi: 10.1016/j.euroneuro.2013.11.002. Epub 2013 Nov 15.
Cannabidiol as a potential treatment for psychosis.
Schubart CD1, Sommer IE2, Fusar-Poli P3, de Witte L2, Kahn RS1, Boks MP4.
Author information
Abstract
Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the development of psychosis and provides an overview of currently available animal, human experimental, imaging, epidemiological and clinical studies that investigated the antipsychotic properties of CBD. In this targeted literature review we performed a search for English articles using Medline and EMBASE. Studies were selected if they described experiments with psychosis models, psychotic symptoms or psychotic disorders as outcome measure and involved the use of CBD as intervention. Evidence from several research domains suggests that CBD shows potential for antipsychotic treatment.
© 2013 Published by Elsevier B.V. and ECNP.
http://www.ncbi.nlm.nih.gov/pubmed/24309088
Eur Neuropsychopharmacol. 2014 Jan;24(1):51-64. doi: 10.1016/j.euroneuro.2013.11.002. Epub 2013 Nov 15.
Cannabidiol as a potential treatment for psychosis.
Schubart CD1, Sommer IE2, Fusar-Poli P3, de Witte L2, Kahn RS1, Boks MP4.
Author information
Abstract
Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the development of psychosis and provides an overview of currently available animal, human experimental, imaging, epidemiological and clinical studies that investigated the antipsychotic properties of CBD. In this targeted literature review we performed a search for English articles using Medline and EMBASE. Studies were selected if they described experiments with psychosis models, psychotic symptoms or psychotic disorders as outcome measure and involved the use of CBD as intervention. Evidence from several research domains suggests that CBD shows potential for antipsychotic treatment.
© 2013 Published by Elsevier B.V. and ECNP.
http://www.ncbi.nlm.nih.gov/pubmed/24309088
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