Generex Biotechnology Corporatio (GNBT) 0.0190 $GNBT
Generex Announces Presentation at the Society for Immunotherapy of Cancer Demonstrating that Induction of Antibody Response in Patients Receiving the AE37 Breast Cancer Vaccine Correlates with Reduced Relapse
PR Newswire - Tue Nov 11, 8:30AM CST
Generex Biotechnology Corporation (www.generex.com) (OTCQB: GNBT) today announced a presentation showing that induction of an antibody response to the HER2 target of its AE37 cancer vaccine correlated with a reduction of relapse in breast cancer patients. The AE37 cancer vaccine is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The presentation was part of the 29th Annual Meeting & Associated Programs of the Society for Immunotherapy of Cancer (SITC) (www.sitcancer.org) that was held November 6-9, 2014 in National Harbor, MD.
Global Breast Cancer Vaccine Clinical Trial Insight
M2 - Wed Oct 29, 11:04AM CDT
Research and Markets (http://www.researchandmarkets.com/research/z2zwt4/global_breast) has announced the addition of the "Global Breast Cancer Vaccine Clinical Trial Insight" report to their offering. Cancer vaccines have emerged a viable option for treating multiple cancers which in the present day scenario do not have effective treatments. Therapeutic cancer vaccines and Prophylactic cancer vaccines are the two broad segments into which the cancer vaccines market is categorized. Therapeutic or Treatment vaccines are targeted at treating an existing cancer by strengthening the body's natural defenses against the cancer while the Prophylactic or Preventive vaccines are used to prevent cancer from developing in healthy people. With the approval of the prostate cancer vaccine, Provenge by Dendreon, the field of cancer vaccines has received an unprecedented boost. Consequently, many companies are expected to enter this highly profitable emerging field of preventing, treating, and potentially curing the cancer. In last few years, the peptide cancer vaccines have been demonstrating potential in clinical trials for the treatment of breast cancer. The high versatility and easy modification capabilities have made them widely acceptable among oncologists. They are sometimes developed to target over expressed receptors specific to the breast cancer cells. These vaccines stimulate a cancer patients' immune system to identify and eliminate breast cancer cells. Clinical trials have also shown the efficacy of peptide vaccines in shrinking breast cancer. This has encouraged the oncologists to develop better breast cancer vaccine for patients. The development and deciphering of underlying principle of breast cancer vaccine will improve significantly driven by technological advancement occurred in recent years. Innovative products developed in this way will decrease the development time and will also help in cost arbitrage. Without cost effectiveness it would be difficult for pharmaceutical companies to compete and occupy substantial share in breast cancer market. However, it is expected that the cost of these vaccines would be high at the time of introduction which will subsequently decrease due to availability of other vaccines in same category. It is most likely that the first breast cancer vaccines would be introduced in market in the next 3-5 years period. Clinical trials would be able to come with thoroughly checked version of products under investigation which would be able to provide higher levels of medical care to breast cancer patients. Most of the innovative products are at the final stages of clinical trials which are supposed to clear the targeted end points. Global Breast Cancer Vaccine Clinical Trial Insight Report Highlight: - Global Breast Cancer Vaccine Market Overview - Global Breast Cancer Vaccine Clinical Pipeline by Company, Phase & Country - Mechanism of Breast Cancer Vaccine & Personalized Cancer Vaccines - Detailed Clinical Insight on Breast Cancer Vaccine Pipeline: 35 Vaccines - Majority in PHASE-I Clinical Trial: 12 Vaccines - Highest Clinical Phase is PHASE-III: 2 Vaccines (NeuVax & OBI-822) Key Topics Covered: 1. Global Breast Cancer Vaccine Market Overview 2. Global Breast Cancer Vaccine Market Dynamics 3. Mechanism of Breast Cancer Vaccine 4. Personalized Cancer Vaccines: Progress & Possibilities 5. Global Breast Cancer Vaccine Market Future Prospects 6. Global Breast Cancer Vaccines Pipeline by Phase, Company & Country 7. Suspended & Discontinued Breast Cancer Vaccines Pipeline by Phase, Company & Country 8. Competitive Landscape - AlphaVax - Galena Biopharma - Generex Biotechnology - GlaxoSmithKline - Immune Design - Immunovaccine - Immunovative Therapies - Imugene - TapImmune - ViroMed For more information visit http://www.researchandmarkets.com/research/z2...bal_breast
IMDZ: 35.22 (-0.75), GALE: 1.87 (-0.01), GSK: 45.74 (+0.08)
Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons
PR Newswire - Mon Oct 27, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCQB: GNBT) today announced two presentations demonstrating that the extent of the immunological response triggered by its novel proprietary cancer immunotherapeutic AE37 vaccine correlated with a reduction of relapse in breast cancer patients. The AE37 cancer vaccine is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The presentations are being made at the American College of Surgeons Clinical Congress 2014, being held October 26-30, 2014 in San Francisco, CA.
Generex / Antigen Express to Participate in 2014 BIO-Europe® Annual International Partnering Conference
PR Newswire - Thu Oct 23, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be participating in the 2014 BIO-Europe® Annual International Partnering Conference being held November 3-5 in Frankfurt, Germany.
Generex Announces Publication of Ebola Vaccine White Paper by Antigen Express
PR Newswire - Tue Oct 21, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that its wholly owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), has issued a white paper outlining the advantages of its Ii-Key technology in the development of an effective Ebola vaccine.
Generex Clarifies Utility of Antigen Express Technology for Potential Ebola Vaccine
PR Newswire - Tue Oct 07, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today responded to a recent article posted to the Seeking Alpha website (http://seekingalpha.com/article/2533015-with-ebola-looming-when-will-the-defense-department-get-around-to-generex) regarding the need for an Ebola vaccine and the importance of providing funding for small companies with technologies applicable to such an endeavor. Generex is the parent company of Antigen Express, Inc. (www.antigenexpress.com), which focuses on the development of synthetic peptide vaccines for significant unmet medical needs.
Generex hires Dr Lakshmi P. Kotra for buccal insulin enhancement project
M2 - Wed Oct 01, 6:12AM CDT
Drug delivery company Generex Biotechnology (Other OTC :GNBT) said on Tuesday that it has engaged Dr Lakshmi P. Kotra, B. Pharm(Hons), PhD to provide consultancy, expertise and assistance in the management of its buccal insulin enhancement project.
Generex Announces Engagement of Dr. Lakshmi P. Kotra for Buccal Insulin Enhancement Project
PR Newswire - Tue Sep 30, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that it has engaged Dr. Lakshmi P. Kotra, B. Pharm.(Hons), Ph.D., as a consultant to the Company to provide expertise and assistance in the management of the Company's previously announced buccal insulin enhancement project. In this role, Dr. Kotra will work closely with the Company's Senior Scientific Advisor, Dr. James H. Anderson, Jr., MD, and Company management working to increase the insulin bioavailability of Generex Oral-lyn(TM), the Company's proprietary buccal insulin spray product, thereby reducing the number of puffs required to achieve effective prandial metabolic control for patients with diabetes.
Generex Collaborates with University Health Network for Buccal Insulin Project
PR Newswire - Mon Sep 22, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that it has entered into a collaboration with University Health Network (UHN) pursuant to which UHN's Centre for Molecular Design and Preformulations (CMDP) will spearhead the Company's buccal insulin refinement project. The goal of the project is to increase the insulin bioavailability of Generex Oral-lyn(TM), the Company's proprietary buccal insulin spray product, thereby reducing the number of puffs required to achieve effective prandial metabolic control for patients with diabetes. This research will ensure the product is more attractive to patients and prospective commercialization partners.
Generex / Antigen Express to Participate in BioPharm America(TM) 2014
PR Newswire - Wed Sep 03, 8:15AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be participating in the 7th Annual International Partnering Conference BioPharm America(TM) 2014 being held September 22-24 in Boston. The conference is a significant business development forum for companies like Antigen Express, providing access to high-level executives and influential decision makers who attend the forum to liaise with key players in the industry, form partnerships, and evaluate emerging technologies. Antigen Express launched its strategic partnering program at the BIO International Convention in San Diego in June, 2014.
Generex Announces Publication of AE37 Prostate Cancer Vaccine Study
PR Newswire - Wed Aug 06, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced publication of a follow-up study from a Phase I clinical trial of the immunotherapeutic agent AE37 in patients with prostate cancer. The study demonstrates an association between a specific immune response generated by AE37 and improved overall survival. The compound is being developed by Antigen Express, Inc. (www.antigenexpress.com), a wholly-owned subsidiary of Generex, for multiple cancer indications.
H5N1 Infection (Avian Influenza) - Pipeline Review, H1 2014
M2 - Tue Jul 15, 11:03AM CDT
Research and Markets (http://www.researchandmarkets.com/research/748t6b/h5n1_infection) has announced the addition of the "H5N1 Infection (Avian Influenza) - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for H5N1 Infection (Avian Influenza), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for H5N1 Infection (Avian Influenza) and special features on late-stage and discontinued projects. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Scope - The report provides a snapshot of the global therapeutic landscape of H5N1 Infection (Avian Influenza) - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for H5N1 Infection (Avian Influenza) and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the H5N1 Infection (Avian Influenza) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the H5N1 Infection (Avian Influenza) pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Companies Mentioned - Johnson & Johnson - Autoimmune Technologies, LLC - GlaxoSmithKline plc - Inovio Pharmaceuticals, Inc. - Daiichi Sankyo Company, Limited - Emergent BioSolutions Inc. - Generex Biotechnology Corporation - Takeda Pharmaceutical Company Limited - Nanotherapeutics, Inc. - Novartis AG - CEL-SCI Corporation - OPKO Health, Inc. - Hemispherx Biopharma, Inc. - Medicago Inc. - BioDiem Ltd - NanoViricides, Inc. - Medigen Biotechnology Corporation - SIGA Technologies, Inc. - XOMA Corporation - Green Cross Corporation - Antigen Express, Inc. - Adimmune Corporation - TechnoVax, Inc. - Cocrystal Pharma, Inc. - PaxVax - Vivaldi Biosciences Inc. - Aprogen, Inc. - Akshaya Bio Inc. - Gemmus Pharma Inc. For more information visit http://www.researchandmarkets.com/research/74..._infection
CVM: 0.65 (+0.04), EBS: 24.22 (-0.10), GSK: 45.74 (+0.08), NNVC: 3.39 (-0.08), SIGA: 1.60 (-0.07), JNJ: 108.16 (-0.91), OPK: 8.29 (-0.05), XOMA: 3.92 (-0.05), NVS: 93.95 (-0.43)
Global Type 1 Diabetes Market 2014-2018 with Astrazeneca, Eli Lilly and Co, Novo Nordisk A/S & Sanofi-Aventis US Dominating
M2 - Mon Jun 23, 4:28AM CDT
Research and Markets (http://www.researchandmarkets.com/research/5k8cfq/global_type_1) has announced the addition of the "Global Type 1 Diabetes Market 2014-2018 with Astrazeneca, Eli Lilly and Co, Novo Nordisk A/S & Sanofi-Aventis US Dominating" report to their offering. The Global Type 1 Diabetes Market will grow at a CAGR of 6.9% over the period 2013-2018. One of the main drivers in this market is the increase in the global type 1 diabetic population. The global type 1 diabetes population is increasing every year with an annual increase of 3 percent in children below 14 years of age. An increase in the type 1 diabetic population might increase the number of people opting for treatment. This will drive the sale and revenue of these drugs. The key vendors in the Global Type 1 Diabetes market are increasing their penetration in the emerging markets. Recent years have witnessed an increase in investment in manufacturing sites based in these countries with the intention to enhance the production of drugs such as insulin for local or global markets. For instance, the Frankfurt site is a key manufacturer for Sanofi diabetes products. However, Sanofi has invested in Russia for its Orel-based site to enable the production of insulin prefilled devices. For a similar category of products, Sanofi has also invested in a manufacturing site in Beijing to penetrate the market. Recently, Sanofi transferred the manufacturing technologies for Insuman insulin to Shantha Biotech in India (part of the Sanofi group). In 2009, Novo Nordisk completely transferred the production of NovoPen from Denmark to Tianjin. Also, in 2008, Novo Nordisk started the construction of an advanced insulin filling plant in Tianjin, which is expected to cater to the demand of the Chinese market for Penfill, the insulin based solution for injection in cartridges. Further, the report states that one of the major challenges is the side effects of current therapies for type 1 diabetes. A lack of effective treatment that can manage glucose levels without causing adverse effects considerably decreases effective disease management. Key Vendors - Astrazeneca plc - Eli Lilly and Co. - Novo Nordisk A/S - Sanofi-Aventis US LLC Other Prominent Vendors - Biodel Inc. - Diamyd Medical AB - DiaVacs Inc. - Generex Biotechnology Corp. - Lexicon Pharmaceuticals Inc. - Macrogenics Inc. - MannKind Corp. - Osiris Therapeutics Inc. - Tolerion Inc. - XOMA Corp. For more information visit http://www.researchandmarkets.com/research/5k...bal_type_1
NVO: 44.13 (+0.11), LXRX: 1.28 (-0.05), OSIR: 13.05 (-0.25), LLY: 67.33 (-0.35), BIOD: 1.59 (+0.04), XOMA: 3.92 (-0.05)
Generex Announces Interview of Dr. Eric von Hofe, President of Antigen Express, Following Recent Keynote Presentation
PR Newswire - Tue Jun 17, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced the posting of an interview given by Dr. Eric von Hofe, Ph.D., President of the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), following his keynote presentation at the recent TIDES meeting. The 16th Annual TIDES Conference (www.IBCLifeSciences.com/Tides) was held in Providence, RI May 12 - 15, 2014. TIDES, Oligonucleotide and Peptide® Therapeutics from Research through Commercialization, is the premier meeting focused on the discovery and development of synthetic biologicals. The interview can be viewed online at:
Generex/Antigen Express Announce Interview of MD Anderson's Dr. Elizabeth Mittendorf, Principal Investigator on Company's AE37 Phase IIb Breast Cancer Efficacy Trial
PR Newswire - Thu Jun 12, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced an interview given by Dr. Elizabeth Mittendorf, M.D., Ph.D. Dr. Mittendorf is the Principal Investigator of the AE37 clinical trial to test the ability of the novel immunotherapeutic agent to prevent relapse in patients who have had HER2-expressing breast cancer, the largest Phase IIb peptide clinical trial conducted to date. AE37 is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The interview was conducted by Oncology TV at this year's Annual Meeting of the American Society of Clinical Oncology (ASCO), held in Chicago from May 30 to June 3. The interview can be viewed online at:
Generex Announces $2,075,000 Capital Investment
PR Newswire - Thu Mar 27, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that it entered into a securities purchase agreement with certain institutional investors on March 27, 2014. The investors have agreed to purchase in a private placement an aggregate of 2,075 shares of the Company's newly designated non-voting Series F 9% Convertible Preferred Stock ("convertible preferred stock"
and warrants to purchase up to an aggregate of 100% of the shares of its common stock issuable upon conversion of the convertible preferred stock ("warrants" at the closing. The convertible preferred stock and warrants will be sold in units, with each unit consisting of one share of convertible preferred stock and a warrant to purchase 100% of the shares of the Company's common stock issuable upon conversion of such shares of convertible preferred stock. Each unit will be sold at a negotiated price of $1,000 for an aggregate purchase price of $2,075,000. An aggregate of 138,333,333 shares of the Company's common stock will be issuable upon conversion of, or exercise of, the convertible preferred stock and warrants issued at the closing. In addition, until the one year anniversary of the date of closing, each investor may, in its sole determination, elect to purchase, severally and not jointly with the other investors, in one or more purchases, in the ratio of such investor's original subscription amount to the original aggregate subscription amount of all investors, additional units consisting of convertible preferred stock and warrants at a purchase price of $1,000 per unit with an aggregate subscription amount thereof of up to $2,075,000, which units will be identical to the units of convertible preferred stock and warrants issued in connection with the initial closing.
Generex/Antigen Express Announces Participation on Panel at Upcoming Cancer Immunotherapeutics Symposium
PR Newswire - Wed Mar 26, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that Dr. Eric von Hofe, Ph.D., the President of its wholly-owned immunotherapeutics subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be a member of a panel discussing immunotherapies for solid tumors at the Fourth Annual "Cancer Immunotherapy: A Long-Awaited Reality" conference at the New York Academy of Medicine in New York City on March 27, 2014. This unique, single-day conference event unites founding visionary researchers, clinicians, business leaders, key investors, and other stakeholders to engage in discussions, exchange information, highlight opportunities, and showcase leading companies in the field of cancer immunotherapy.
Generex Biotechnology Corp. Granted Patents on New HPV and Influenza Vaccines
ACCESSWIRE - Wed Mar 12, 11:01AM CDT
Generex Biotechnology Corp. (OTCQB: GNBT) stock volume soared Mar. 11, with 9,325,106 shares changing hands, significantly higher than its three-month average volume of 7,012,285 shares.
Generex Biotechnology wins patents for vaccines targeting HPV induced cancers and influenza
M2 - Thu Mar 06, 6:05AM CST
Drug delivery company Generex Biotechnology (Other OTC:GNBT), based in Canada, reported on Wednesday the receipt of the US Patent Office's Notices of Allowance relating to applications for the use of therapeutic vaccines targeting cancers caused by human papilloma virus (HPV) as well as potentially pandemic strains of the influenza virus.
Generex Subsidiary Antigen Express Receives Patents for Vaccines Targeting HPV Induced Cancers and Influenza
PR Newswire - Wed Mar 05, 8:30AM CST
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that its wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com) has received Notices of Allowance from the United States Patent Office relating to applications for the use of therapeutic vaccines targeting human papilloma virus (HPV) caused cancers as well as to potentially pandemic strains of influenza virus. The Company has previously received allowances of broad claims surrounding the use of its Ii-Key hybrid technology platform. Both applications relate to vaccines designed using this platform, which was also used to design its AE37 vaccine that is currently in a late Phase II trial to prevent relapse in patients who have had breast cancer.
Generex Announces Presentation at the Society for Immunotherapy of Cancer Demonstrating that Induction of Antibody Response in Patients Receiving the AE37 Breast Cancer Vaccine Correlates with Reduced Relapse
PR Newswire - Tue Nov 11, 8:30AM CST
Generex Biotechnology Corporation (www.generex.com) (OTCQB: GNBT) today announced a presentation showing that induction of an antibody response to the HER2 target of its AE37 cancer vaccine correlated with a reduction of relapse in breast cancer patients. The AE37 cancer vaccine is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The presentation was part of the 29th Annual Meeting & Associated Programs of the Society for Immunotherapy of Cancer (SITC) (www.sitcancer.org) that was held November 6-9, 2014 in National Harbor, MD.
Global Breast Cancer Vaccine Clinical Trial Insight
M2 - Wed Oct 29, 11:04AM CDT
Research and Markets (http://www.researchandmarkets.com/research/z2zwt4/global_breast) has announced the addition of the "Global Breast Cancer Vaccine Clinical Trial Insight" report to their offering. Cancer vaccines have emerged a viable option for treating multiple cancers which in the present day scenario do not have effective treatments. Therapeutic cancer vaccines and Prophylactic cancer vaccines are the two broad segments into which the cancer vaccines market is categorized. Therapeutic or Treatment vaccines are targeted at treating an existing cancer by strengthening the body's natural defenses against the cancer while the Prophylactic or Preventive vaccines are used to prevent cancer from developing in healthy people. With the approval of the prostate cancer vaccine, Provenge by Dendreon, the field of cancer vaccines has received an unprecedented boost. Consequently, many companies are expected to enter this highly profitable emerging field of preventing, treating, and potentially curing the cancer. In last few years, the peptide cancer vaccines have been demonstrating potential in clinical trials for the treatment of breast cancer. The high versatility and easy modification capabilities have made them widely acceptable among oncologists. They are sometimes developed to target over expressed receptors specific to the breast cancer cells. These vaccines stimulate a cancer patients' immune system to identify and eliminate breast cancer cells. Clinical trials have also shown the efficacy of peptide vaccines in shrinking breast cancer. This has encouraged the oncologists to develop better breast cancer vaccine for patients. The development and deciphering of underlying principle of breast cancer vaccine will improve significantly driven by technological advancement occurred in recent years. Innovative products developed in this way will decrease the development time and will also help in cost arbitrage. Without cost effectiveness it would be difficult for pharmaceutical companies to compete and occupy substantial share in breast cancer market. However, it is expected that the cost of these vaccines would be high at the time of introduction which will subsequently decrease due to availability of other vaccines in same category. It is most likely that the first breast cancer vaccines would be introduced in market in the next 3-5 years period. Clinical trials would be able to come with thoroughly checked version of products under investigation which would be able to provide higher levels of medical care to breast cancer patients. Most of the innovative products are at the final stages of clinical trials which are supposed to clear the targeted end points. Global Breast Cancer Vaccine Clinical Trial Insight Report Highlight: - Global Breast Cancer Vaccine Market Overview - Global Breast Cancer Vaccine Clinical Pipeline by Company, Phase & Country - Mechanism of Breast Cancer Vaccine & Personalized Cancer Vaccines - Detailed Clinical Insight on Breast Cancer Vaccine Pipeline: 35 Vaccines - Majority in PHASE-I Clinical Trial: 12 Vaccines - Highest Clinical Phase is PHASE-III: 2 Vaccines (NeuVax & OBI-822) Key Topics Covered: 1. Global Breast Cancer Vaccine Market Overview 2. Global Breast Cancer Vaccine Market Dynamics 3. Mechanism of Breast Cancer Vaccine 4. Personalized Cancer Vaccines: Progress & Possibilities 5. Global Breast Cancer Vaccine Market Future Prospects 6. Global Breast Cancer Vaccines Pipeline by Phase, Company & Country 7. Suspended & Discontinued Breast Cancer Vaccines Pipeline by Phase, Company & Country 8. Competitive Landscape - AlphaVax - Galena Biopharma - Generex Biotechnology - GlaxoSmithKline - Immune Design - Immunovaccine - Immunovative Therapies - Imugene - TapImmune - ViroMed For more information visit http://www.researchandmarkets.com/research/z2...bal_breast
IMDZ: 35.22 (-0.75), GALE: 1.87 (-0.01), GSK: 45.74 (+0.08)
Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons
PR Newswire - Mon Oct 27, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCQB: GNBT) today announced two presentations demonstrating that the extent of the immunological response triggered by its novel proprietary cancer immunotherapeutic AE37 vaccine correlated with a reduction of relapse in breast cancer patients. The AE37 cancer vaccine is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The presentations are being made at the American College of Surgeons Clinical Congress 2014, being held October 26-30, 2014 in San Francisco, CA.
Generex / Antigen Express to Participate in 2014 BIO-Europe® Annual International Partnering Conference
PR Newswire - Thu Oct 23, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be participating in the 2014 BIO-Europe® Annual International Partnering Conference being held November 3-5 in Frankfurt, Germany.
Generex Announces Publication of Ebola Vaccine White Paper by Antigen Express
PR Newswire - Tue Oct 21, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that its wholly owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), has issued a white paper outlining the advantages of its Ii-Key technology in the development of an effective Ebola vaccine.
Generex Clarifies Utility of Antigen Express Technology for Potential Ebola Vaccine
PR Newswire - Tue Oct 07, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today responded to a recent article posted to the Seeking Alpha website (http://seekingalpha.com/article/2533015-with-ebola-looming-when-will-the-defense-department-get-around-to-generex) regarding the need for an Ebola vaccine and the importance of providing funding for small companies with technologies applicable to such an endeavor. Generex is the parent company of Antigen Express, Inc. (www.antigenexpress.com), which focuses on the development of synthetic peptide vaccines for significant unmet medical needs.
Generex hires Dr Lakshmi P. Kotra for buccal insulin enhancement project
M2 - Wed Oct 01, 6:12AM CDT
Drug delivery company Generex Biotechnology (Other OTC :GNBT) said on Tuesday that it has engaged Dr Lakshmi P. Kotra, B. Pharm(Hons), PhD to provide consultancy, expertise and assistance in the management of its buccal insulin enhancement project.
Generex Announces Engagement of Dr. Lakshmi P. Kotra for Buccal Insulin Enhancement Project
PR Newswire - Tue Sep 30, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that it has engaged Dr. Lakshmi P. Kotra, B. Pharm.(Hons), Ph.D., as a consultant to the Company to provide expertise and assistance in the management of the Company's previously announced buccal insulin enhancement project. In this role, Dr. Kotra will work closely with the Company's Senior Scientific Advisor, Dr. James H. Anderson, Jr., MD, and Company management working to increase the insulin bioavailability of Generex Oral-lyn(TM), the Company's proprietary buccal insulin spray product, thereby reducing the number of puffs required to achieve effective prandial metabolic control for patients with diabetes.
Generex Collaborates with University Health Network for Buccal Insulin Project
PR Newswire - Mon Sep 22, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that it has entered into a collaboration with University Health Network (UHN) pursuant to which UHN's Centre for Molecular Design and Preformulations (CMDP) will spearhead the Company's buccal insulin refinement project. The goal of the project is to increase the insulin bioavailability of Generex Oral-lyn(TM), the Company's proprietary buccal insulin spray product, thereby reducing the number of puffs required to achieve effective prandial metabolic control for patients with diabetes. This research will ensure the product is more attractive to patients and prospective commercialization partners.
Generex / Antigen Express to Participate in BioPharm America(TM) 2014
PR Newswire - Wed Sep 03, 8:15AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be participating in the 7th Annual International Partnering Conference BioPharm America(TM) 2014 being held September 22-24 in Boston. The conference is a significant business development forum for companies like Antigen Express, providing access to high-level executives and influential decision makers who attend the forum to liaise with key players in the industry, form partnerships, and evaluate emerging technologies. Antigen Express launched its strategic partnering program at the BIO International Convention in San Diego in June, 2014.
Generex Announces Publication of AE37 Prostate Cancer Vaccine Study
PR Newswire - Wed Aug 06, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced publication of a follow-up study from a Phase I clinical trial of the immunotherapeutic agent AE37 in patients with prostate cancer. The study demonstrates an association between a specific immune response generated by AE37 and improved overall survival. The compound is being developed by Antigen Express, Inc. (www.antigenexpress.com), a wholly-owned subsidiary of Generex, for multiple cancer indications.
H5N1 Infection (Avian Influenza) - Pipeline Review, H1 2014
M2 - Tue Jul 15, 11:03AM CDT
Research and Markets (http://www.researchandmarkets.com/research/748t6b/h5n1_infection) has announced the addition of the "H5N1 Infection (Avian Influenza) - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for H5N1 Infection (Avian Influenza), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for H5N1 Infection (Avian Influenza) and special features on late-stage and discontinued projects. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Scope - The report provides a snapshot of the global therapeutic landscape of H5N1 Infection (Avian Influenza) - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for H5N1 Infection (Avian Influenza) and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the H5N1 Infection (Avian Influenza) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the H5N1 Infection (Avian Influenza) pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Companies Mentioned - Johnson & Johnson - Autoimmune Technologies, LLC - GlaxoSmithKline plc - Inovio Pharmaceuticals, Inc. - Daiichi Sankyo Company, Limited - Emergent BioSolutions Inc. - Generex Biotechnology Corporation - Takeda Pharmaceutical Company Limited - Nanotherapeutics, Inc. - Novartis AG - CEL-SCI Corporation - OPKO Health, Inc. - Hemispherx Biopharma, Inc. - Medicago Inc. - BioDiem Ltd - NanoViricides, Inc. - Medigen Biotechnology Corporation - SIGA Technologies, Inc. - XOMA Corporation - Green Cross Corporation - Antigen Express, Inc. - Adimmune Corporation - TechnoVax, Inc. - Cocrystal Pharma, Inc. - PaxVax - Vivaldi Biosciences Inc. - Aprogen, Inc. - Akshaya Bio Inc. - Gemmus Pharma Inc. For more information visit http://www.researchandmarkets.com/research/74..._infection
CVM: 0.65 (+0.04), EBS: 24.22 (-0.10), GSK: 45.74 (+0.08), NNVC: 3.39 (-0.08), SIGA: 1.60 (-0.07), JNJ: 108.16 (-0.91), OPK: 8.29 (-0.05), XOMA: 3.92 (-0.05), NVS: 93.95 (-0.43)
Global Type 1 Diabetes Market 2014-2018 with Astrazeneca, Eli Lilly and Co, Novo Nordisk A/S & Sanofi-Aventis US Dominating
M2 - Mon Jun 23, 4:28AM CDT
Research and Markets (http://www.researchandmarkets.com/research/5k8cfq/global_type_1) has announced the addition of the "Global Type 1 Diabetes Market 2014-2018 with Astrazeneca, Eli Lilly and Co, Novo Nordisk A/S & Sanofi-Aventis US Dominating" report to their offering. The Global Type 1 Diabetes Market will grow at a CAGR of 6.9% over the period 2013-2018. One of the main drivers in this market is the increase in the global type 1 diabetic population. The global type 1 diabetes population is increasing every year with an annual increase of 3 percent in children below 14 years of age. An increase in the type 1 diabetic population might increase the number of people opting for treatment. This will drive the sale and revenue of these drugs. The key vendors in the Global Type 1 Diabetes market are increasing their penetration in the emerging markets. Recent years have witnessed an increase in investment in manufacturing sites based in these countries with the intention to enhance the production of drugs such as insulin for local or global markets. For instance, the Frankfurt site is a key manufacturer for Sanofi diabetes products. However, Sanofi has invested in Russia for its Orel-based site to enable the production of insulin prefilled devices. For a similar category of products, Sanofi has also invested in a manufacturing site in Beijing to penetrate the market. Recently, Sanofi transferred the manufacturing technologies for Insuman insulin to Shantha Biotech in India (part of the Sanofi group). In 2009, Novo Nordisk completely transferred the production of NovoPen from Denmark to Tianjin. Also, in 2008, Novo Nordisk started the construction of an advanced insulin filling plant in Tianjin, which is expected to cater to the demand of the Chinese market for Penfill, the insulin based solution for injection in cartridges. Further, the report states that one of the major challenges is the side effects of current therapies for type 1 diabetes. A lack of effective treatment that can manage glucose levels without causing adverse effects considerably decreases effective disease management. Key Vendors - Astrazeneca plc - Eli Lilly and Co. - Novo Nordisk A/S - Sanofi-Aventis US LLC Other Prominent Vendors - Biodel Inc. - Diamyd Medical AB - DiaVacs Inc. - Generex Biotechnology Corp. - Lexicon Pharmaceuticals Inc. - Macrogenics Inc. - MannKind Corp. - Osiris Therapeutics Inc. - Tolerion Inc. - XOMA Corp. For more information visit http://www.researchandmarkets.com/research/5k...bal_type_1
NVO: 44.13 (+0.11), LXRX: 1.28 (-0.05), OSIR: 13.05 (-0.25), LLY: 67.33 (-0.35), BIOD: 1.59 (+0.04), XOMA: 3.92 (-0.05)
Generex Announces Interview of Dr. Eric von Hofe, President of Antigen Express, Following Recent Keynote Presentation
PR Newswire - Tue Jun 17, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced the posting of an interview given by Dr. Eric von Hofe, Ph.D., President of the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), following his keynote presentation at the recent TIDES meeting. The 16th Annual TIDES Conference (www.IBCLifeSciences.com/Tides) was held in Providence, RI May 12 - 15, 2014. TIDES, Oligonucleotide and Peptide® Therapeutics from Research through Commercialization, is the premier meeting focused on the discovery and development of synthetic biologicals. The interview can be viewed online at:
Generex/Antigen Express Announce Interview of MD Anderson's Dr. Elizabeth Mittendorf, Principal Investigator on Company's AE37 Phase IIb Breast Cancer Efficacy Trial
PR Newswire - Thu Jun 12, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced an interview given by Dr. Elizabeth Mittendorf, M.D., Ph.D. Dr. Mittendorf is the Principal Investigator of the AE37 clinical trial to test the ability of the novel immunotherapeutic agent to prevent relapse in patients who have had HER2-expressing breast cancer, the largest Phase IIb peptide clinical trial conducted to date. AE37 is being developed by the Company's wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com). The interview was conducted by Oncology TV at this year's Annual Meeting of the American Society of Clinical Oncology (ASCO), held in Chicago from May 30 to June 3. The interview can be viewed online at:
Generex Announces $2,075,000 Capital Investment
PR Newswire - Thu Mar 27, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that it entered into a securities purchase agreement with certain institutional investors on March 27, 2014. The investors have agreed to purchase in a private placement an aggregate of 2,075 shares of the Company's newly designated non-voting Series F 9% Convertible Preferred Stock ("convertible preferred stock"
and warrants to purchase up to an aggregate of 100% of the shares of its common stock issuable upon conversion of the convertible preferred stock ("warrants" at the closing. The convertible preferred stock and warrants will be sold in units, with each unit consisting of one share of convertible preferred stock and a warrant to purchase 100% of the shares of the Company's common stock issuable upon conversion of such shares of convertible preferred stock. Each unit will be sold at a negotiated price of $1,000 for an aggregate purchase price of $2,075,000. An aggregate of 138,333,333 shares of the Company's common stock will be issuable upon conversion of, or exercise of, the convertible preferred stock and warrants issued at the closing. In addition, until the one year anniversary of the date of closing, each investor may, in its sole determination, elect to purchase, severally and not jointly with the other investors, in one or more purchases, in the ratio of such investor's original subscription amount to the original aggregate subscription amount of all investors, additional units consisting of convertible preferred stock and warrants at a purchase price of $1,000 per unit with an aggregate subscription amount thereof of up to $2,075,000, which units will be identical to the units of convertible preferred stock and warrants issued in connection with the initial closing. Generex/Antigen Express Announces Participation on Panel at Upcoming Cancer Immunotherapeutics Symposium
PR Newswire - Wed Mar 26, 8:30AM CDT
Generex Biotechnology Corporation (www.generex.com) (OTCBB:GNBT) today announced that Dr. Eric von Hofe, Ph.D., the President of its wholly-owned immunotherapeutics subsidiary, Antigen Express, Inc. (www.antigenexpress.com), will be a member of a panel discussing immunotherapies for solid tumors at the Fourth Annual "Cancer Immunotherapy: A Long-Awaited Reality" conference at the New York Academy of Medicine in New York City on March 27, 2014. This unique, single-day conference event unites founding visionary researchers, clinicians, business leaders, key investors, and other stakeholders to engage in discussions, exchange information, highlight opportunities, and showcase leading companies in the field of cancer immunotherapy.
Generex Biotechnology Corp. Granted Patents on New HPV and Influenza Vaccines
ACCESSWIRE - Wed Mar 12, 11:01AM CDT
Generex Biotechnology Corp. (OTCQB: GNBT) stock volume soared Mar. 11, with 9,325,106 shares changing hands, significantly higher than its three-month average volume of 7,012,285 shares.
Generex Biotechnology wins patents for vaccines targeting HPV induced cancers and influenza
M2 - Thu Mar 06, 6:05AM CST
Drug delivery company Generex Biotechnology (Other OTC:GNBT), based in Canada, reported on Wednesday the receipt of the US Patent Office's Notices of Allowance relating to applications for the use of therapeutic vaccines targeting cancers caused by human papilloma virus (HPV) as well as potentially pandemic strains of the influenza virus.
Generex Subsidiary Antigen Express Receives Patents for Vaccines Targeting HPV Induced Cancers and Influenza
PR Newswire - Wed Mar 05, 8:30AM CST
Generex Biotechnology Corporation (www.generex.com) (OTCBB: GNBT) today announced that its wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com) has received Notices of Allowance from the United States Patent Office relating to applications for the use of therapeutic vaccines targeting human papilloma virus (HPV) caused cancers as well as to potentially pandemic strains of influenza virus. The Company has previously received allowances of broad claims surrounding the use of its Ii-Key hybrid technology platform. Both applications relate to vaccines designed using this platform, which was also used to design its AE37 vaccine that is currently in a late Phase II trial to prevent relapse in patients who have had breast cancer.
