SBFM News $SBFM Ebola Virus Infections Could P
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Posted On: 11/05/2014 6:03:34 AM
SBFM News $SBFM
Ebola Virus Infections Could Potentially Be Treated With Sunshine Biopharma's Lead Anticancer Compound, Adva-27a
ACCESSWIRE - Mon Nov 03, 4:00AM CST
Montreal, Quebec / ACCESSWIRE / November 3, 2014 / Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has conducted a scientific review of the mechanisms by which Ebola virus penetrates human cells and takes over their machinery to multiply rapidly and go on to infecting other cells leading to massive cell destruction and ultimately death in nearly 80% of the cases. The review found that the progression of Ebola virus infection is very similar to that of Influenza A virus, the causative agent that was responsible for the death of over 90 million people in the 1918 flu pandemic. In severe Influenza A virus infections, a condition associated with high mortality rate called haemophagocytic lymphohistiocytosis (HLH) is developed by the affected patient. HLH has previously been treated successfully with Etoposide which increased survivability from 50% to 90% (LANCET, Volume 367, Pages 870-873, March 2006). Etoposide is an anticancer drug that inhibits the activity Topoisomerase II, an essential enzyme found in hyperactive, rapidly growing cells such as cancer cells and HLH cells. Like Etoposide, Sunshine Biopharma's lead anticancer compound, Adva-27a, is a Topoisomerase II inhibitor however it has been shown to be more effective and less toxic than Etoposide (ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). The latter characteristics make Adva-27a superior to Etoposide for possible treatment of Ebola patients with already weakened state of health.
Sunshine Biopharma Retains Renmark Financial Communications to Provide Investor Relations
Marketwired - Tue Oct 14, 7:06AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, including its proprietary lead anticancer compound Adva-27a, today announced that it has retained the services of Renmark Financial Communications Inc. to handle its investor relations activities.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Completes the SOP's Required by Health Canada to Secure Drug Establishment License
Marketwire - Wed Oct 01, 7:02AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has completed the drafting of all of the Standard Operating Procedures (SOP's) required by Health Canada for the procurement of a Drug Establishment License (DEL). The completed SOP's comprise 18 binders and over 2,000 pages of documentation. It is necessary for Sunshine to have the DEL in place in order to become a fully integrated pharmaceutical company with proprietary (Adva-27a) and generic pharmaceutical products offering.
Sunshine Biopharma Negotiating With CRO's to Initiate Master Drug File for Adva-27a Anticancer Compound
Marketwire - Wed Sep 03, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it is currently negotiating with several Contract Research Organizations (CRO's) with the intent to engage one of them for the purposes of initiating, compiling and managing a regulatory master drug file for Adva-27a, the Company's flagship anticancer compound. A master drug file contains all of the information that regulatory agencies require as part of the drug development and approval process. Such information includes preclinical data, GMP manufacturing process, large animal studies and human trials.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Engages Health Canada Specialized Consultants to Secure Pharmaceutical Establishment License
ACCESSWIRE - Thu Aug 21, 7:01AM CDT
Montreal, Quebec, Canada / ACCESSWIRE / August 21, 2014 / Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has engaged consultants specialized in Health Canada procedures and requirements to prepare the necessary documentations and applications for the procurement of a Pharmaceutical Establishment License. Such licensing must be in place before the Company is able to sign manufacturing and distribution contracts and accept purchase orders for the sale of pharmaceutical products.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Secures Dedicated Space to Commence Global Generic Pharmaceutical Operations
Marketwire - Mon Aug 11, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has secured dedicated space in order to commence operations in the generic pharmaceuticals business as planned. Having a specifically dedicated space is required in order for the Company to be granted a Pharmaceutical Establishment and Export License by Health Canada. Once we secure our Establishment Licensed we will be in a position to sign manufacturing and distribution contracts for sale of generic pharmaceuticals in Canada and elsewhere around the globe. According to various estimates, the annual worldwide market for generic pharmaceuticals which Sunshine Biopharma's Canadian subsidiary is positioning itself to participate in is in excess of $100 billion.
Sunshine Biopharma Launches Sunshine Biopharma Canada Inc., a Wholly Owned Canadian Subsidiary in Anticipation of Signing Manufacturing and Commercialization Contracts in Canada
Marketwire - Tue Jul 29, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has formed Sunshine Biopharma Canada Inc., a Canadian wholly owned subsidiary for the purposes of conducting pharmaceutical business in Canada and elsewhere around the globe. Sunshine Biopharma anticipates that Sunshine Biopharma Canada will soon sign manufacturing, marketing, sales and distribution contracts for various pharmaceutical and biomedical products. According to various estimates, the worldwide market for generic pharmaceuticals which Sunshine Biopharma Canada is positioning itself to participate in is in excess of $100 billion per year.
Management of Sunshine Biopharma Alarmed by the Recent World Health Organization Report That Cancer Is on the Rise
Marketwire - Mon Mar 31, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, has issued a response to the recently released reports by the World Health Organization and the Pancreatic Cancer Action Network.
Jang Attributes Peaceful Council Elections to Security Arrangements
by Seriki Adinoyi - All Africa Global Media - Wed Feb 26, 1:34AM CST
Governor Jonah Jang of Plateau State has attributed the peaceful conduct of the local government area elections in the state to the adequate security measures put in place for the exercise.
Sunshine Biopharma Continues Its Efforts to Re-Domicile in Canada for Business Expansion and Financing Opportunities for Adva-27a Cancer Drug Candidate
Marketwire Canada - Tue Feb 04, 7:00AM CST
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of proprietary drugs for the treatment of various forms of cancer, today announced that it is continuing its efforts to re-domiciling the Company in Canada in order to capitalize on management's belief that by doing so, the Company will generate additional business expansion opportunities and gain access to financing programs available to Canadian corporations. On January 31, 2014, the Company filed an S-4 Registration Statement wherein it is attempting to re-domicile to Canada from Colorado.
Sunshine Biopharma Targets Pancreatic Cancer as Second Indication for Clinical Trials of Adva-27a Compound
Marketwire Canada - Tue Jan 21, 7:08AM CST
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it is now targeting pancreatic cancer as a second indication for Adva-27a, the Company's flagship anticancer drug candidate. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of approximately 4 micromolar, a pharmacologically very favorable drug concentration. Based on initial data, the Company is moving forward with intentions to conduct a Phase I clinical trial of Adva-27a for pancreatic cancer in parallel to the planned Phase I clinical trial of Adva-27a for breast cancer that is scheduled to be hosted at McGill University's Jewish General Hospital in Montreal.
Galectin Shares Rise on IND Filing, is Sunshine Biopharma Next in Line?
ACCESSWIRE - Wed Sep 18, 7:21AM CDT
Drug development is a business that can be a minefield; littered with pieces of failed companies that couldn't manage expenses and compounds that failed to meet expectations. The beauty of biotechnology, though, is a level playing field in which companies can grow robust valuations based upon target indications and assets, even at early stages of development. With initiatives around the world to expedite the regulatory pathway and major pharmaceutical companies hungry for acquisitions, there probably isn't a better time to be looking at some well-positioned up-and-comers in the space.
GALT: 5.47 (-0.09)
OTC Daily Alert Stock Watch - Sunshine Biopharma Inc., (OTCQB: SBFM)
WorldStockWire - Wed Sep 11, 10:15PM CDT
OTC Daily Alert tracks stocks daily and is pleased to offer features on public companies. Investors can receive FREE Stock Alerts and company news and profiles by visiting OTC Daily Alert at the following: http://www.otcdailyalert.com
Sunshine Biopharma Parent Company Acquires Garmen Laboratories, a Certified GMP Manufacturing Lab
Marketwire - Mon Aug 26, 7:01AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announces that its parent company, Advanomics Corporation, has signed a binding agreement to acquire Garmen Laboratories (Laboratoires Garmen Inc.), a Good Manufacturing Practices (GMP) laboratory with 45 employees providing complete pharmaceutical manufacturing and testing services to a broad range of industrial, institutional and governmental agencies. A profitable company, Garmen Laboratories is headquartered in a 50,000-square-foot, state-of-the-art facility in Montreal, Canada. With nearly 35 years of industry experience, Garmen delivers an array of solutions that can help detect, identify and quantify trace-level chemical components in the nutraceutical, food and pharmaceutical industries.
Ebola Virus Infections Could Potentially Be Treated With Sunshine Biopharma's Lead Anticancer Compound, Adva-27a
ACCESSWIRE - Mon Nov 03, 4:00AM CST
Montreal, Quebec / ACCESSWIRE / November 3, 2014 / Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has conducted a scientific review of the mechanisms by which Ebola virus penetrates human cells and takes over their machinery to multiply rapidly and go on to infecting other cells leading to massive cell destruction and ultimately death in nearly 80% of the cases. The review found that the progression of Ebola virus infection is very similar to that of Influenza A virus, the causative agent that was responsible for the death of over 90 million people in the 1918 flu pandemic. In severe Influenza A virus infections, a condition associated with high mortality rate called haemophagocytic lymphohistiocytosis (HLH) is developed by the affected patient. HLH has previously been treated successfully with Etoposide which increased survivability from 50% to 90% (LANCET, Volume 367, Pages 870-873, March 2006). Etoposide is an anticancer drug that inhibits the activity Topoisomerase II, an essential enzyme found in hyperactive, rapidly growing cells such as cancer cells and HLH cells. Like Etoposide, Sunshine Biopharma's lead anticancer compound, Adva-27a, is a Topoisomerase II inhibitor however it has been shown to be more effective and less toxic than Etoposide (ANTICANCER RESEARCH, Volume 32, Pages 4423-4432, October 2012). The latter characteristics make Adva-27a superior to Etoposide for possible treatment of Ebola patients with already weakened state of health.
Sunshine Biopharma Retains Renmark Financial Communications to Provide Investor Relations
Marketwired - Tue Oct 14, 7:06AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, including its proprietary lead anticancer compound Adva-27a, today announced that it has retained the services of Renmark Financial Communications Inc. to handle its investor relations activities.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Completes the SOP's Required by Health Canada to Secure Drug Establishment License
Marketwire - Wed Oct 01, 7:02AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has completed the drafting of all of the Standard Operating Procedures (SOP's) required by Health Canada for the procurement of a Drug Establishment License (DEL). The completed SOP's comprise 18 binders and over 2,000 pages of documentation. It is necessary for Sunshine to have the DEL in place in order to become a fully integrated pharmaceutical company with proprietary (Adva-27a) and generic pharmaceutical products offering.
Sunshine Biopharma Negotiating With CRO's to Initiate Master Drug File for Adva-27a Anticancer Compound
Marketwire - Wed Sep 03, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it is currently negotiating with several Contract Research Organizations (CRO's) with the intent to engage one of them for the purposes of initiating, compiling and managing a regulatory master drug file for Adva-27a, the Company's flagship anticancer compound. A master drug file contains all of the information that regulatory agencies require as part of the drug development and approval process. Such information includes preclinical data, GMP manufacturing process, large animal studies and human trials.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Engages Health Canada Specialized Consultants to Secure Pharmaceutical Establishment License
ACCESSWIRE - Thu Aug 21, 7:01AM CDT
Montreal, Quebec, Canada / ACCESSWIRE / August 21, 2014 / Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has engaged consultants specialized in Health Canada procedures and requirements to prepare the necessary documentations and applications for the procurement of a Pharmaceutical Establishment License. Such licensing must be in place before the Company is able to sign manufacturing and distribution contracts and accept purchase orders for the sale of pharmaceutical products.
Sunshine Biopharma's Wholly Owned Canadian Subsidiary Secures Dedicated Space to Commence Global Generic Pharmaceutical Operations
Marketwire - Mon Aug 11, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that its wholly owned Canadian subsidiary has secured dedicated space in order to commence operations in the generic pharmaceuticals business as planned. Having a specifically dedicated space is required in order for the Company to be granted a Pharmaceutical Establishment and Export License by Health Canada. Once we secure our Establishment Licensed we will be in a position to sign manufacturing and distribution contracts for sale of generic pharmaceuticals in Canada and elsewhere around the globe. According to various estimates, the annual worldwide market for generic pharmaceuticals which Sunshine Biopharma's Canadian subsidiary is positioning itself to participate in is in excess of $100 billion.
Sunshine Biopharma Launches Sunshine Biopharma Canada Inc., a Wholly Owned Canadian Subsidiary in Anticipation of Signing Manufacturing and Commercialization Contracts in Canada
Marketwire - Tue Jul 29, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it has formed Sunshine Biopharma Canada Inc., a Canadian wholly owned subsidiary for the purposes of conducting pharmaceutical business in Canada and elsewhere around the globe. Sunshine Biopharma anticipates that Sunshine Biopharma Canada will soon sign manufacturing, marketing, sales and distribution contracts for various pharmaceutical and biomedical products. According to various estimates, the worldwide market for generic pharmaceuticals which Sunshine Biopharma Canada is positioning itself to participate in is in excess of $100 billion per year.
Management of Sunshine Biopharma Alarmed by the Recent World Health Organization Report That Cancer Is on the Rise
Marketwire - Mon Mar 31, 7:03AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, has issued a response to the recently released reports by the World Health Organization and the Pancreatic Cancer Action Network.
Jang Attributes Peaceful Council Elections to Security Arrangements
by Seriki Adinoyi - All Africa Global Media - Wed Feb 26, 1:34AM CST
Governor Jonah Jang of Plateau State has attributed the peaceful conduct of the local government area elections in the state to the adequate security measures put in place for the exercise.
Sunshine Biopharma Continues Its Efforts to Re-Domicile in Canada for Business Expansion and Financing Opportunities for Adva-27a Cancer Drug Candidate
Marketwire Canada - Tue Feb 04, 7:00AM CST
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of proprietary drugs for the treatment of various forms of cancer, today announced that it is continuing its efforts to re-domiciling the Company in Canada in order to capitalize on management's belief that by doing so, the Company will generate additional business expansion opportunities and gain access to financing programs available to Canadian corporations. On January 31, 2014, the Company filed an S-4 Registration Statement wherein it is attempting to re-domicile to Canada from Colorado.
Sunshine Biopharma Targets Pancreatic Cancer as Second Indication for Clinical Trials of Adva-27a Compound
Marketwire Canada - Tue Jan 21, 7:08AM CST
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it is now targeting pancreatic cancer as a second indication for Adva-27a, the Company's flagship anticancer drug candidate. As previously announced (see press release dated June 4, 2013), Adva-27a, a Topoisomerase II inhibitor, was found to be effective at destroying cells of the very aggressive pancreatic cancer cell line, Panc-1. Adva-27a was able to kill these cells with an IC50 of approximately 4 micromolar, a pharmacologically very favorable drug concentration. Based on initial data, the Company is moving forward with intentions to conduct a Phase I clinical trial of Adva-27a for pancreatic cancer in parallel to the planned Phase I clinical trial of Adva-27a for breast cancer that is scheduled to be hosted at McGill University's Jewish General Hospital in Montreal.
Galectin Shares Rise on IND Filing, is Sunshine Biopharma Next in Line?
ACCESSWIRE - Wed Sep 18, 7:21AM CDT
Drug development is a business that can be a minefield; littered with pieces of failed companies that couldn't manage expenses and compounds that failed to meet expectations. The beauty of biotechnology, though, is a level playing field in which companies can grow robust valuations based upon target indications and assets, even at early stages of development. With initiatives around the world to expedite the regulatory pathway and major pharmaceutical companies hungry for acquisitions, there probably isn't a better time to be looking at some well-positioned up-and-comers in the space.
GALT: 5.47 (-0.09)
OTC Daily Alert Stock Watch - Sunshine Biopharma Inc., (OTCQB: SBFM)
WorldStockWire - Wed Sep 11, 10:15PM CDT
OTC Daily Alert tracks stocks daily and is pleased to offer features on public companies. Investors can receive FREE Stock Alerts and company news and profiles by visiting OTC Daily Alert at the following: http://www.otcdailyalert.com
Sunshine Biopharma Parent Company Acquires Garmen Laboratories, a Certified GMP Manufacturing Lab
Marketwire - Mon Aug 26, 7:01AM CDT
Sunshine Biopharma Inc. (OTCQB: SBFM), a pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announces that its parent company, Advanomics Corporation, has signed a binding agreement to acquire Garmen Laboratories (Laboratoires Garmen Inc.), a Good Manufacturing Practices (GMP) laboratory with 45 employees providing complete pharmaceutical manufacturing and testing services to a broad range of industrial, institutional and governmental agencies. A profitable company, Garmen Laboratories is headquartered in a 50,000-square-foot, state-of-the-art facility in Montreal, Canada. With nearly 35 years of industry experience, Garmen delivers an array of solutions that can help detect, identify and quantify trace-level chemical components in the nutraceutical, food and pharmaceutical industries.
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