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PharmaPoint: Major Depressive Disorder - Global Drug Forecast and Market Analysis to 2023
M2 - Thu Sep 25, 5:39AM CDT
Research and Markets (http://www.researchandmarkets.com/research/9vx7ff/pharmapoint) has announced the addition of the "PharmaPoint: Major Depressive Disorder - Global Drug Forecast and Market Analysis to 2023" report to their offering. Product Launches and Patent Expiries to Push Major Depressive Disorder Treatment Market through Fluctuating Growth Period by 2023 This report provides an overview of Major Depressive Disorder (MDD), including epidemiology, etiology, pathophysiology, symptoms, diagnosis and current treatment options. The key topics covered include strategic competitor assessment, market characterization, unmet needs and implications for the MDD therapeutics market. The therapeutics market for Major Depressive Disorder (MDD) will face a dynamic phase up until the end of 2023, thanks to the potential launch of new treatments following the patent expirations of top-selling products, says a new report from research and consulting firm The authors. According to the company's latest report*, the MDD treatment market achieved sales of approximately $9.3 billion in 2013 across the seven major markets (7MM: the US, France, Germany, Italy, Spain, the UK and Japan) and Australia. These sales will witness minimal growth by the end of 2023, reaching an estimated $9.7 billion, at a Compound Annual Growth Rate (CAGR) of 0.39%. However, The authors forecasts that the market value will first undergo a decline until 2017, with sales dropping to $7.3 billion. This can be attributed mainly to the expirations of patents for Eli Lilly's Cymbalta, Otsuka Pharmaceutical/BMS' Abilify and AstraZeneca's Seroquel XR. The authors states that there are already seven products in the late-stage pipeline that could enter the MDD market during the forecast period. These include adjunctive therapies, such as Otsuka/Lundbeck's brexpiprazole, Forest (Actavis)/Gedeon Richter/Mitsubishi Tanabe Pharma's cariprazine, Alkermes's ALKS-5461 and Naurex's GLYX-13, along with antidepressant therapies, including Euthymics Bioscience's amitifadine, Lundbeck/Takeda's tedatioxetine and e-Therapeutics' ETS6103. Koutsokeras continues: All seven of these pipeline drugs show promise as safer and more efficacious treatments for MDD patients, while GLYX-13 and ETS6103 in particular boast the potential to provide rapid antidepressant effects. With their ability to address some of the MDD treatment market's key unmet needs, we believe that these products' launches could well spark its return to growth in 2018. Other driving factors behind the reversal in its decline will be the increasing uptake of Lundbeck/Takeda's Brintellix, combined with the expanding number of MDD prevalent cases that we expect to see by the end of 2023. Key Topics Covered: 1 Tables & Figures 2 Introduction 3 Disease Overview - Etiology and Pathophysiology - Classification - Symptoms and Subtypes of Major Depressive Disorder - Prognosis - Quality of Life 4 Epidemiology - Risk Factors and Comorbidities - Global and Historical Trends - Forecast Methodology - Epidemiological Forecast for MDD (2013-2023) 5 Disease Management - Diagnosis - Treatment Guidelines and Leading Prescribed Drugs - Clinical Practice 6 Competitive Assessment - Lexapro (Escitalopram) - Viibryd (Vilazodone) - Other Selective Serotonin Reuptake Inhibitors - Effexor (Venlafaxine) - Cymbalta (Duloxetine) - Pristiq (Desvenlafaxine) - Fetzima (Levomilnacipran) - Savella (Milnacipran) - Norepinephrine-Dopamine Reuptake Inhibitors - Noradrenaline and Specific Serotonergic Antidepressants - Monoamine Oxidase Inhibitors - Tricyclic Antidepressants - Brintellix (Vortioxetine) - Abilify (Aripiprazole) - Seroquel XR (Quetiapine) 7 Unmet Needs and Opportunities - More Effective Pharmacotherapies - More Favorable Side Effect Profiles - Rapid Onset of Antidepressant Effects - Personalized Treatment Approach 8 Pipeline Assessment - Brexpiprazole (OPC-34712) - Cariprazine (RGH-188) - ALKS-5461 - Amitifadine (EB-1010) - GLYX-13 - Tedatioxetine (Lu AA24530) - ETS6103 - Other Drugs in Development 9 Current and Future Players - Lundbeck - Forest Laboratories (Actavis) - Eli Lilly - Pfizer - Otsuka Pharmaceutical - AstraZeneca - Takeda Pharmaceutical - Alkermes - Euthymics Bioscience - Naurex - e-Therapeutics 10 Market Outlook - Global - US - France - Germany - Italy - Spain - UK - Japan - Australia 11 Appendix For more information visit http://www.researchandmarkets.com/research/9v...harmapoint

Global Hyperglycemia Therapeutics Pipeline Review - H2 2014: 3 Companies and 11 Drug Profiles
M2 - Wed Sep 24, 5:07AM CDT
Research and Markets (http://www.researchandmarkets.com/research/mk64nx/hyperglycemia) has announced the addition of the "Hyperglycemia - Pipeline Review, H2 2014" report to their offering. This report provides comprehensive information on the therapeutic development for Hyperglycemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Hyperglycemia and special features on late-stage and discontinued projects. The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Scope - The report provides a snapshot of the global therapeutic landscape of Hyperglycemia - The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities - The report reviews key players involved in the therapeutics development for Hyperglycemia and enlists all their major and minor projects - The report summarizes all the dormant and discontinued pipeline projects - A review of the Hyperglycemia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources - Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages - A detailed assessment of monotherapy and combination therapy pipeline projects - Coverage of the Hyperglycemia pipeline on the basis of target, MoA, route of administration and molecule type - Latest news and deals relating related to pipeline products Companies Involved in Therapeutics Development - Kissei Pharmaceutical Co., Ltd. - Mitsubishi Tanabe Pharma Corporation - PhaseBio Pharmaceuticals, Inc. Drug Profiles - PE-0139 - Small Molecules to Inhibit SGLT1 for Postprandial Hyperglycemia - KR-62980 - ZLN-005 - Small Molecules to Inhibit PEPCK for Diabetes and Hyperglycemia - Small Molecules to Inhibit Prokineticin Receptor for Metabolic Disorders - 55-P-0251 - Small Molecules to Inhibit DPP-IV for Hyperglycemia - FGH-10019 - Antisense Oligonucleotides to Target ABHD6 for Gastrointestinal and Metabolic Disorders - Small Molecules to Antagonize PST Receptor for Dysglycemic States For more information visit http://www.researchandmarkets.com/research/mk...erglycemia

China Pharmaceutical Guide 2014 - 9th Edition Out Now
M2 - Tue Aug 12, 9:20AM CDT
Research and Markets (http://www.researchandmarkets.com/research/qbjpjg/china) has announced the addition of the "China Pharmaceutical Guide 2014 (9th Edition)" report to their offering. Written by veteran pharma industry executives to help guide international players navigate through thecomplex and turbulent Chinese healthcare business environment, it is the most authoritative reference on China's pharmaceutical and healthcare business. Extensive coverage on China's pharma industry and healthcare sector, structure and market environment, regulatory framework, healthcare provision and financing, disease & drug consumption patterns, pharma sales, marketing & distribution, trends and opportunities, market entry strategies, case studies of successes and failures in six key areas of the Chinese pharma business, and profiles of leading MNC pharma players in China. The 2014 edition has been thoroughly updated with significantly expanded coverage in recent editions on more sub-sectors, outsourcing, clinical practices, regulatory updates on healthcare reform and drug policies, additional case studies, and latest market / health data updated through mid-2014. Key Topics Covered: Part I Overview Of The Chinese Economy And Business Part II The Chinese Pharmaceutical Industry And Market Part III Pharmaceutical Regulatory Framework Part IV Healthcare Provision And Financing Part V Disease And Drug Consumption Patterns Part VI Pharmaceutical Sales, Marketing And Distribution In China Part VII Contemporary Trends, Opportunities And Strategic Considerations Part VIII Market Entry Strategies And Execution Part IX Mini Case Studies Part X Company Profiles: Multinational Pharma Companies In China Companies Mentioned - Abbvie China (Abbott) - Astellas China - AstraZeneca China - Baxter Healthcare China - Bayer Healthcare China - Beaufour Ipsen China - Boehringer Ingelheim China - Bristol-Myers Squibb China - DSM China - Daiichi Sankyo China - Dainippon Sumitomo Pharma China - Eisai China - Eli Lilly China - Fresenius Kabi China - GE Healthcare China - GlaxoSmithKline China - Johnson & Johnson China - Kyowa Hakko Kirin China - Merck KGAA/Merck Serono China - Merck Sharp & Dhome China - Mitsubishi Tanabe Pharma China - Novartis China - Novo Nordisk China - Otsuka China - Pfizer China - Roche China - Sanofi China - Stada China - TEVA China - Takeda China For more information visit http://www.researchandmarkets.com/research/qbjpjg/china

Global Rheumatoid Arthritis Drugs Market 2014-2018
M2 - Mon Jul 28, 6:54AM CDT
Research and Markets (http://www.researchandmarkets.com/research/tv2rn2/global_rheumatoid) has announced the addition of the "Global Rheumatoid Arthritis Drugs Market 2014-2018" report to their offering. RA is a chronic disease that leads to inflammation and pain in the human body's joints such as wrists, fingers, knees, feet, and ankles. In addition, it causes inflammation of the tissues that surround the joints and in other organs. The symptoms of RA begin slowly, usually just mild pain around the joints coupled with stiffness and fatigue, and in the later stages it causes inflammation of the joints. It can occur at any age, even in children, which is called juvenile arthritis. The disease is three times more common in women than in men. Genetic and environmental elements are known to contribute in the development of RA. The analysts forecast the Global Rheumatoid Arthritis Drugs market will grow at a CAGR of 4.09 percent over the period 2013-2018. Key Topics Covered: 01. Executive Summary 02. List of Abbreviations 03. Scope of the Report 04. Market Research Methodology 05. Introduction 06. Market Landscape 07. Competitive Assessment of Top Drugs 08. Five Forces Analysis 09. Market Segmentation by Category 10. Geographical Segmentation 11. Buying Criteria 12. Rate of Incidence and Prevalence 13. Pipeline Snapshot 14. Market Growth Drivers 15. Drivers and their Impact 16. Market Challenges 17. Impact of Drivers and Challenges 18. Market Trends 19. Trends and their Impact 20. Vendor Landscape 21. Key Vendor Analysis 22. Other Reports in this Series Companies Mentioned: - AbbVie Inc. - Amgen Inc. - Bristol-Myers Squibb Co. - F. Hoffmann-La Roche Ltd. - Janssen Pharmaceuticals Inc. - Pfizer Inc. - AB Science SA - Astellas Pharma Inc. - AstraZeneca plc - Biogen Idec Inc. - Boehringer Ingelheim GmbH - Celgene Corp. - Daiichi Sankyo Co. Ltd. - Eli Lilly & Co. - GE Healthcare Co. - Genmab A/S - GSK plc - Incyte Corp. - Merck & Co. Inc. - Mitsubishi Tanabe Pharma Corp. - Novartis AG - Novo Nordisk A/S - Rigel Pharmaceuticals Inc. - Sanofi - Takeda Pharmaceutical Co. Ltd. - UCB SA - Vertex Pharmaceuticals Inc. For more information visit http://www.researchandmarkets.com/research/tv...rheumatoid

PharmaPoint: Major Depressive Disorder - Japan Drug Forecast and Market Analysis to 2023
M2 - Tue Jun 17, 6:29AM CDT
Research and Markets (http://www.researchandmarkets.com/research/mr4qd6/pharmapoint) has announced the addition of the "PharmaPoint: Major Depressive Disorder - Japan Drug Forecast and Market Analysis to 2023" report to their offering. Major depressive disorder (MDD) is one of the most common psychiatric diseases worldwide. The MDD market is a crowded and competitive market, with more than 30 marketed products available for the treatment of patients with MDD. The depression market is about to enter a dynamic phase with imminent patent expiries for top selling products, such as Eli Lilly's Cymbalta, and Otsuka/BMS's Abilify, along with the recent launch of the multimodal antidepressant, Lundbeck/Takeda's Brintellix, in January 2014, and the potential introduction of seven promising late-stage pipeline products into the market during the forecast period, from 2013 to 2023. The anticipated growth of the depression market in Japan is due to the expected launch of Brintellix and the potential introduction of seven late-stage pipeline products into the market during the forecast period. GlobalData anticipates Elli Lilly's Cymbalta and Lundbeck/Forest (Actavis)/Mitsubishi Tanabe Pharma/Mochida's Lexapro to be the top-selling products by the end of the forecast period in Japan, generating combined sales of approximately $162.2m. Reasons to buy - Understand and capitalize by identifying products that are most likely to ensure a robust return - Stay ahead of the competition by understanding the changing competitive landscape for Major depressive disorder. - Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential - Make more informed business decisions from insightful and in-depth analysis of drug performance - Obtain sales forecast for drugs from 2013-2023 in Japan. Key Topics Covered: 1 Table of Contents 2 Introduction 3 Disease Overview 4 Disease Management 5 Competitive Assessment 6 Unmet Needs and Opportunities 7 Pipeline Assessment 8 Market Outlook 9 Appendix For more information visit http://www.researchandmarkets.com/research/mr...harmapoint

Surveyed U.S. Psychiatrists Would Prescribe EnVivo Pharmaceuticals' Encenicline to 25 Percent of their Patients with Cognitive Impairment Associated with Schizophrenia
PR Newswire - Mon Mar 31, 9:00AM CDT
Decision Resources Group finds that surveyed U.S. psychiatrists would prescribe EnVivo Pharmaceuticals/Bayer HealthCare/Mitsubishi Tanabe Pharma's encenicline to 25 percent of their patients with cognitive impairment associated with schizophrenia (CIAS). Assuming its promising--albeit preliminary--clinical profile is confirmed in ongoing Phase III studies, encenicline could become the first-ever therapy approved to treat this condition, fulfilling a major unmet need in the clinical management of schizophrenia. Surveyed psychiatrists also project patient shares of up to 20 percent for other emerging CIAS drugs, including AbbVie's ABT-126, Omeros's OMS-824, and Avineuro Pharmaceuticals' AVN-211.

Global Generic Drugs Market 2014-2018: Branded Drugs with Sales of Up to US$135 Billion to Go Off-Patent by 2015
M2 - Mon Mar 24, 6:32AM CDT
Research and Markets (http://www.researchandmarkets.com/research/6q8j7g/global_generic) has announced the addition of the "Global Generic Drugs Market 2014-2018" report to their offering. The analysts forecast the Global Generic Drugs market to grow at a CAGR of 11.02 percent over the period 2013-2018. The patent expiry of top-selling drugs is one of the major drivers contributing to the growth of this market. The market is also witnessing an increase in mergers and acquistions. However, intense competition among vendors could squeeze profit margins, increase pricing pressure, and pose a challenge to the growth of this market. Key vendors dominating this space include Actavis plc, Mylan Inc., Novartis International AG (Sandoz), STADA Arzneimittel AG, and Teva Pharmaceutical Industries Ltd. Other vendors mentioned in the report are 3SBio Inc., Amgen Inc., Apotex Inc., AstraZeneca plc, Aurobindo Pharma Ltd., Baxter International Inc., Berlin-Chemie AG, Biocon Ltd., Biogen Idec Inc., Boehringer Ingelheim GmbH, Celltrion Inc., Cipla Ltd., Coherus Biosciences Inc., Daiichi Sankyo Co. Ltd., Dr. Reddy's Laboratories Ltd., Emcure Pharmaceuticals Ltd., Gedeon Richter plc, GlaxoSmithKline plc, Hospira Inc., Impax Laboratories Inc., Intas Pharmaceuticals Ltd., Lupin Ltd., Merck & Co. Inc., Mitsubishi Tanabe Pharma Corp., Par Pharmaceutical Inc., Pfizer Inc., Ranbaxy Laboratories Ltd., Roche Holding AG, Sanofi S.A., Wockhardt Ltd., and Zydus Cadila Healthcare Ltd. Commenting on the report, an analyst from the team said: Mergers and acquisitions has become the core growth strategy among many healthcare vendors; they help vendors grow rapidly and expand their businesses. The Global Generic Drugs market has witnessed a number of mergers and acquisitions among the leading vendors. Vendors have been primarily focusing on mergers and acquisitions to increase their scale, revenue, market share, and competitive advantage. For instance, in November 2012, Actavis acquired Watson Pharmaceuticals and became the third largest generic pharmaceutical company across the globe, with operations in more than 60 countries. In October 2013, Actavis acquired Warner Chilcott plc for approximately US$8.5 billion. Moreover, in 2011, Teva acquired Ratiopharm AG, a leading generic drug manufacturer in Europe, to maintain its position in the market. For more information visit http://www.researchandmarkets.com/research/6q...al_generic About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Concise Analysis of the Future Prospects of Global Personalized Medicine Market
M2 - Tue Mar 04, 5:49AM CST
Research and Markets (http://www.researchandmarkets.com/research/zpctsr/future_prospects) has announced the addition of the "Concise Analysis of the Future Prospects of Global Personalized Medicine Market" report to their offering. Over the years, the Global Personalized Medicine market has been witnessing the emergence of various tools and technologies from the reputed vendors. For instance, AssureRx Health Inc. launched GeneSightRx ADHD in May 2012, a personalized medicine test for the growing number of children and adults diagnosed with ADHD. Moreover, Bristol-Myers Squibb Co. collaborated with MMRF in December 2012 for advanced personalized medicine for multiple Myeloma. Further, Alacris Theranostics GmbH entered into an agreement with GlaxoSmithKline plc in November 2012 to use ModCell system for early stage cancer research. Further, AltheaDx Inc. launched FLT3 Mutation Assay in October 2012. Agendia N.V. launched ColoPrint microarray-based 18-gene expression signature in June 2012 for predicting the risk of distant recurrence for stage II colon cancer patients. The European Medicines Agency approved Zelboraf, manufactured by F. Hoffmann-La Roche Ltd., in December 2011. Key Topics Covered: 1. Executive Summary 2. List of Abbreviations 3. Introduction 4. Market Research Methodology 5. Scope of the Report 6. Market Landscape 7. Geographical Segmentation 8. Key Leading Countries 9. Vendor Landscape 10. Buying Criteria 11. Market Growth Drivers 12. Drivers and their Impact 13. Market Challenges 14. Impact of Drivers and Challenges 15. Market Trends 16. Key Vendor Analysis 17. Other Reports in this Series Companies Mentioned: - Abbott Laboratories - Boehringer Ingelheim GmbH - Bristol-Myers Squibb Co. - Celgene Corp. - Daiichi Sankyo Co. Ltd. - Danaher Corp. - Eli Lilly and Co. - Evotec AG - F. Hoffmann-La Roche Ltd. - GE Healthcare Ltd. - Genelex Corp. - GlaxoSmithKline plc - Hologic Inc. - Johnson & Johnson - Laboratory Corporation of America Holdings - Life Technologies Corp. - Merck KGaA - Mitsubishi Tanabe Pharma Corp. - Myriad Genetics Inc. - Novartis AG - Novartis AG - PerkinElmer Inc. - Pfizer Inc. - Pfizer Inc. - Quest Diagnostics Inc. - Sanofi S.A. - Sanofi S.A. - Siemens Healthcare - Sigma-Aldrich Corp. - Takeda Pharmaceutical Co. Ltd. - Teva Pharmaceutical Industries Ltd. - Thermo Fisher Scientific Inc. - Transgenomic Inc. For more information visit http://www.researchandmarkets.com/research/zp..._prospects

MediMabs Announces the Appointment of Two New Members of the Board of Directors
Marketwire - Thu Feb 20, 10:52AM CST
Ms. Sarita Benchimol, the President and Chief Executive Officer of MediMabs Inc., is pleased to announce the election to the MediMabs Board of Directors of Dr. Randal Chase PhD and Mr. R Martin Wong CPA, CA. Both individuals were elected at the company's shareholder meeting and will be joining the existing board of directors, which includes Dr. Phil Gold CC, OQ, MD, PhD, FRSCopyright, FRCPCopyright, MACP, Dr. Claudio Cuello OC, MD, DSc, FRSCopyright, Mr. Miguel Madanes Eng., and Ms. Sarita Benchimol MSc.

General Anxiety Disorder - Pipeline Review, H2 2013
M2 - Tue Jan 28, 3:27AM CST
Research and Markets (http://www.researchandmarkets.com/research/45w2z8/general_anxiety) has announced the addition of the "General Anxiety Disorder - Pipeline Review, H2 2013" report to their offering. This report provides information on the therapeutic development for General Anxiety Disorder, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for General Anxiety Disorder. General Anxiety Disorder - Pipeline Review, Half Year is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Scope - A snapshot of the global therapeutic scenario for General Anxiety Disorder. - A review of the General Anxiety Disorder products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the General Anxiety Disorder pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - News and deals relating to the products. Reasons to Buy - Identify and understand important and diverse types of therapeutics under development for General Anxiety Disorder. - Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage. - Plan mergers and acquisitions effectively by identifying players of the most promising pipeline. - Devise corrective measures for pipeline projects by understanding General Anxiety Disorder pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline. Companies Mentioned - Edgemont Pharmaceuticals - H. Lundbeck - Mitsubishi Tanabe Pharma Corporation - Rottapharm|Madaus For more information visit http://www.researchandmarkets.com/research/45...al_anxiety About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products.

Mitsubishi Tanabe Pharma Completes Acquisiton of Medicago
PR Newswire - Wed Sep 18, 6:50AM CDT
Mitsubishi Tanabe Pharma Corporation (TSE: 4508) ("Mitsubishi Tanabe Pharma" or "MTPC" and Medicago Inc. (TSX:MDG) announced today the completion of the previously announced acquisition of Medicago Inc. by MTPC.

Medicago Announces Receipt of Final Court Order and Regulatory Approvals for Arrangement with Mitsubishi Tanabe Pharma
PR Newswire - Thu Sep 12, 6:00AM CDT
Medicago Inc. (TSX: MDG; OTCQX: MDCGF) ("Medicago" or the "Company" , a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), is pleased to announce that the Superior Court of Quebec has granted its final order approving the previously announced plan of arrangement (the "Arrangement" involving the Company, Mitsubishi Tanabe Pharma Corporation ("MTPC" and 9284-9686 Québec Inc., a wholly-owned subsidiary of MTPC (the "Purchaser" .

Competitor Analysis: Poly-Adenyl-Ribose Polymerase (PARP) Inhibitors
M2 - Thu Sep 12, 3:05AM CDT
Research and Markets (http://www.researchandmarkets.com/research/d2s635/competitor) has announced the addition of the "Competitor Analysis: Poly-Adenyl-Ribose Polymerase (PARP) Inhibitors" report to their offering. The present Competitive Intelligence report about Poly-Adenyl-Ribose Polymerase (PARP) Inhibitors provides a competitor evaluation in the field of small molecule inhibitors of Poly-Adenyl-Ribose Polymerase (PARP) for the treatment of solid tumors as of August 2013. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report. Poly(ADP-ribose) polymerases (PARPs) play a critical role in several pathways that repair DNA damage. Despite the recent failure of Sanofi's PARP inhibitor iniparib, presentation of results from clinical studies with other PARP inhibitors underlined continued interest in this emerging class of targeted cancer drug candidates. In fact, several companies are entering in clinical phase III evaluation of selective or dual/pan PARP inhibitors. The report includes a compilation of currently active projects in research and development of small molecule Poly-Adenyl-Ribose Polymerase (PARP) inhibitors in oncology. In addition, the report lists company-specific R&D pipelines of PARP inhibitors. Competitor projects are listed in a tabular format providing information on: - Drug Codes - Target / Mechanism of Action - Class of Compound - Company - Product Category - Indication - R&D Stage - additional comments with a hyperlink leading to the source of information. Companies Mentioned - AbbVie - Angion Biomedica - AstraZeneca - BioMarin Pharmaceuticals - Clovis Oncology - Eisai - Eternity Bioscience - Inotek Pharmaceuticals - Mitsubishi Tanabe Pharma - Nerviano Medical Sciences - NewGen Therapeutics - Tesaro - Teva Pharmaceutical Industries For more information visit http://www.researchandmarkets.com/research/d2s635/competitor About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Obesity - Pipeline Review, H2 2013
M2 - Mon Sep 09, 5:37AM CDT
Research and Markets (http://www.researchandmarkets.com/research/8nk97f/obesity) has announced the addition of the "Obesity - Pipeline Review, H2 2013" report to their offering. 'Obesity - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Obesity, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Obesity. Scope - A snapshot of the global therapeutic scenario for Obesity. - A review of the Obesity products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Obesity pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Mentioned Boehringer Ingelheim GmbH Shionogi & Co., Ltd. Amgen Inc. Sanofi-Aventis AstraZeneca PLC Eli Lilly and Company Athersys, Inc. GlaxoSmithKline plc Isis Pharmaceuticals, Inc. Merck & Co., Inc. Novo Nordisk A/S Takeda Pharmaceutical Company Limited Plexxikon Inc. BioLineRx, Ltd. Ipsen S.A. Chong Kun Dang Pharmaceutical Glenmark Pharmaceuticals Ltd. GTx, Inc. Kissei Pharmaceutical Co., Ltd. Mitsubishi Tanabe Pharma Corporation Norgine Limited and much more... For more information visit http://www.researchandmarkets.com/research/8nk97f/obesity About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Urinary Incontinence - Pipeline Review, H2 2013
M2 - Fri Sep 06, 2:16AM CDT
Research and Markets (http://www.researchandmarkets.com/research/gnq99s/urinary) has announced the addition of the "Urinary Incontinence - Pipeline Review, H2 2013" report to their offering. 'Urinary Incontinence - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Urinary Incontinence, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Urinary Incontinence. Scope - A snapshot of the global therapeutic scenario for Urinary Incontinence. - A review of the Urinary Incontinence products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Urinary Incontinence pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Mentioned Cook Medical Incorporated Allergan, Inc. Astellas Pharma Inc. Mitsubishi Tanabe Pharma Corporation Recordati S.p.A. Addex Pharmaceuticals Evotec Aktiengesellschaft Plethora Solutions Holdings plc Melior Discovery, Inc. Fate Therapeutics, Inc. Celogos Sinil Pharma Ltd. Beech Tree Labs, Inc. For more information visit http://www.researchandmarkets.com/research/gnq99s/urinary About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Amyotrophic Lateral Sclerosis - Pipeline Review, H2 2013 comes Complete with Latest Updates
M2 - Thu Sep 05, 10:04AM CDT
Research and Markets (http://www.researchandmarkets.com/research/kg6q26/amyotrophic) has announced the addition of the "Amyotrophic Lateral Sclerosis - Pipeline Review, H2 2013" report to their offering. Global Markets Direct's, 'Amyotrophic Lateral Sclerosis - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Amyotrophic Lateral Sclerosis and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Amyotrophic Lateral Sclerosis. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - A snapshot of the global therapeutic scenario for Amyotrophic Lateral Sclerosis. - A review of the Amyotrophic Lateral Sclerosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Amyotrophic Lateral Sclerosis pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Mentioned: - Aeolus Pharmaceuticals, Inc. - Amorfix Life Sciences Ltd. - Biogen Idec Inc. - BrainStorm Cell Therapeutics Inc. - California Stem Cell, Inc. - Cellceutix Corporation - Ceregene, Inc. - Cytokinetics, Inc - D-Pharm Ltd. - Daval International Ltd. - Eisai Co., Ltd. - Genzyme Corporation - GlaxoSmithKline plc - Hadasit Medical Research Services & Development Ltd - Isis Pharmaceuticals, Inc. - Isotechnika Pharma Inc. - Jeil Pharmaceutical Co., Ltd. - KineMed, Inc. - Kringle Pharma, Inc. - M's Science Corporation - Maas Biolab - MediPost Co., Ltd. - miRagen Therapeutics, Inc. - Mitsubishi Tanabe Pharma Corporation - Neuralstem, Inc. - Neuraltus Pharmaceuticals, Inc. - Neurimmune Therapeutics AG - NeuroNova AB - Nexgenix Pharmaceuticals, LLC - Novartis AG - Nutra Pharma Corporation - Oxford BioMedica plc - Paladin Labs Inc. - Pharmagenesis, Inc. - Pharnext SAS - Q Therapeutics, Inc. - Questcor Pharmaceuticals, Inc. - Reata Pharmaceuticals, Inc. - RhinoCyte, Inc. - SCYNEXIS, Inc. - Snowdon Inc. - Trophos SA - Varinel, Inc. For more information visit http://www.researchandmarkets.com/research/kg...myotrophic About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Global Insomnia Report - Pipeline Review Analysis
M2 - Wed Sep 04, 10:33AM CDT
Research and Markets (http://www.researchandmarkets.com/research/gvqfpz/insomnia) has announced the addition of the "Insomnia - Pipeline Review, H2 2013" report to their offering. 'Insomnia - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Insomnia, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Insomnia. Scope - A snapshot of the global therapeutic scenario for Insomnia. - A review of the Insomnia products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Insomnia pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Involved in Insomnia Therapeutics Development - Merck & Co., Inc. - Actelion Ltd - Eisai Co., Ltd. - Mitsubishi Tanabe Pharma Corporation - Evotec Aktiengesellschaft - IntelGenx Technologies Corp. - Neurim Pharmaceuticals Ltd. - Intas Pharmaceuticals Ltd. - Angelini Group - Abeille Pharmaceuticals, Inc. - Intec Pharma ltd. - Ferrer Internacional S.A. - Somnus Therapeutics, Inc. - Intra-Cellular Therapies, Inc. - Kuhnil Pharmaceutical Co., Ltd. - Heptares Therapeutics Ltd. Drug Profiles - suvorexant - suvorexant - Piromelatine - AB-1003 - osemozotan - zaleplon DR - EVT-201 - Orexin-2 - ITI-007 - CR-5542 Series - melatonin - filorexant - zaleplon - INAQUL-001 - eszopiclone - Drug Targeting Orexin 1/2 - E-2006 - trazodone hydrochloride - UCM-765 - Orexin Receptor Antagonist - lorediplon - KI-1001 - Orexin-1 Antagonist - Dual Orexin Receptor Antagonists For more information visit http://www.researchandmarkets.com/research/gvqfpz/insomnia




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