CELLCEUTIX GENERAL OVERVIEW AND DD - IF YOU ARE

CELLCEUTIX GENERAL OVERVIEW AND DD - IF YOU ARE NEW TO CTIX - READ THIS FIRST!

Hello Fellow Investors,

This one is on the verge of a dramatic breakout. This company has several promising compounds in the works, and has been progressing towards starting clinical trials on its flagship cancer drug, kevetrin. In my opinion, this will be THE breakout drug that leads the next generation charge of cancer treatments. Phase 1 clinical trials for its cancer treatment are beginning on/around Nov 1, 2012 and trial data will be a powerful catalyst that will launch this stock to previously unattained levels.

In addition to Kevetrin, there are several other promising compounds in the CTIX pipeline, especially Prurisol – a psoriasis compound which has shown dramatic results in lab testing so far, and is currently being fast tracked to phase 2/3 trials. (as of Nov 2,2012)

F or most micro biotechs, a compound with the potential of Prurisol alone could serve as the flagship compound that could provide great value and ROI to potential shareholders. The fact that Prurisol, a potential billion dollar treatment in its own right, is absolutely dwarfed by the massive potential of Kevetrin as a broad band cancer treatment speaks volumes in itself. There is an incredible opportunity for CTIX to be THE next big breakout biotech company that could offer transformational and life changing profits for those investors who are willing to boldly invest in CTIX at an early stage.



Here is a top line summary about the company, for those wishing to start their own due diligence:

Cellceutix Corporate Bio Summary:

Chief Executive Officer and CFO : Leo Ehrlich, CPA : A founder of Cellceutix, he has served as Chief Financial Officer (CFO) and Director since inception in June 2007 and as CEO since November 2010. From 1999 to December 2007, Mr. Ehrlich had been a director at StatSure Diagnostic Systems, Inc. and has held different executive officer positions at that company including CEO, President and CFO . Mr. Ehrlich was also was a founder, CFO and director at Nanoviricides, Inc. from June 1, 2005. until May 2007. Mr. Ehrlich is a Certified Public Accountant and received his BBA from Bernard Baruch College of the City University of New York.

Chief Scientific Officer : Dr. Krishna Menon: Nearly 30 highly-relevant years in the drug development industry including being a recipient of the President’s Award during his time as a Research Associate at Eli Lilly for his instrumental role in choosing Alimta and Gemzar for development as cancer therapies. These blockbuster chemotherapies are still two of the most widely used drugs today and generated more than $3.3 billion in sales last year alone.

Scientific Advisory Board Member : Dr. Emil Frei: Widely regarded as one of the world’s leading oncologists with more than 40 years’ experience. His accomplishments include former Physician-in-Chief at the Dana-Farber Cancer Institute (where he still resides as Physician-in-Chief, Emeritus) and Chief of Medicine at the National Cancer Institute. If the name rings a bell, it’s because he was mentioned earlier for his role in the cure for childhood leukemia

Scientific Advisory Board Member : Dr. Samuel Danishefsky: Widely regarded as one of the world's leading chemists in cancer research, PhD in Chemistry from Harvard, recipient of the First Annual AACR-CICR Award for Outstanding Achievement in Chemistry in Cancer Research and Chairman of the Laboratory for Cancer Research Bioorganic Chemistry for Memorial Sloan-Kettering Cancer Center

Consultant Dr. Ashok Kumar : Dr. Kumar is a highly-regarded Molecular Biologist who received his Ph.D. from Jawaharlal Nehru University, one of the most prestigious schools in India, recipient of a Japan Society of Promotion of Sciences fellowship from the Government of Japan, extensively published in top scientific journals in the area of Immunology and Molecular Biology and until just recently, a faculty member in the Dept. of Immunology, Mayo Clinic, Rochester, MN

Advisor and Patent Attorney Dr. Paul Ginsberg : Dr. Ginsberg is the former Head of the New York Patent Department at Pfizer, Inc. where he represented Pfizer and their blockbuster drugs Viagra and Chantix on the intellectual property committees of the National Association of Manufacturers, the Chemical Manufacturers Association and the Biotechnology Industry Organization. He is perhaps most well-known as the author of the patent covering Schering-Plough's hugely successful product Claritin

When a company has this many big names in the industry standing behind its developments, it tends to swing open doors of opportunity to “Big Pharma” due to their connections and industry recognition

Kevetrin (the "flagship" CTIX compound) Summary:

Simply put, Kevetrin is a powerful compound that has so far shown astonishing results in lab testing against multiple different strains of treatment resistant, advanced stage cancers (lung, prostate, colon, pancreatic, etc. etc.)

Kevetrin is a small molecule that is different in structure from all currently marketed cancer drugs. It is water-soluble and simple to synthesize from commercially available starting materials

Kevetrin works by doing something no other drug has ever done before, activating the P53 gene, often called "the guardian angel of the human genome" - this is a potent cancer fighting gene that is deactivated or corrupted in over 50% of all cancer cases worldwide, regardless of cancer type

It is important to note, that this is a cancer drug that is revolutionary, not evolutionary - as it is an entirely new and novel type of treatment that has never been used in this medical capacity before

Kevetrin essentially gives your body a "genetic rebuild" to a degree, re-activating the powerful P53 gene that is active and working properly in the average healthy person

Researchers have been trying to accomplish this feat for decades – spending hundreds of millions of dollars in the process – only to come up short

Kevetrin is the first known non-geno toxic cancer drug that successfully activates the P53 gene as the mechanism of action – it has demonstrated that it can finally do what researchers have failed to accomplish for so long

It is very important to remember - Kevetrin is NON-geno toxic . This drug does not harm surrounding healthy DNA

Most cancer treatments in trials today fail because of high toxicity, and this is part of what makes Kevetrin such a compelling treatment, the non-geno toxic nature of the drug

Today’s cancer treatments are still a figurative “bull in a china shop”. They come into your body, and attack cancers aggressively, however they also attack the host as well

Kevetrin works by re-building your body’s cancer “attack dog”, without harming surrounding DNA, a much more humane and advanced way of attacking the disease and not the patient

The man behind the drug, Dr Krishna Menon, is a world renowned cancer researcher who has already helped successfully bring to market multiple other billion dollar cancer drugs (Gemzar and Alimta – both multi-billion dollar drugs)

Kevetrin is set to start its already paid for phase 1 clinical trials at Harvard's Dana Farber Cancer Institute, IMO the world's premiere cancer research and treatment facility – this phase 1 trial is set to start on or around 11/1/12

Normal phase 1 trials test on healthy volunteers and test primarily for safety. Cancer trial drugs are often given to Stage 4 terminally ill patients who usually have cancers that are already resistant to all existing therapies. Since these are the patients Cellceutix is anxious to treat, positive results could springboard development to fast-track status

The way that Dana Farber has laid out the clinical trial for Kevetrin is brilliant in the respect that it offers the FDA the exact and specific data points that will make it easier fro them to justify designating Kevetrin as a “breakthrough technology” therefore accelerating trials even beyond normal “fast tracking” status

Kevetrin will also concurrently be running an already paid for combined phase 1 trial with some of Pfizer's premiere cancer drugs – as CTIX has already signed a non-disclosure agreement with Pfizer

Cellceutix is also in negotiations with one of Europe's most distinguished Leukemia research schools, for a trial that will also be paid for by the University, saving Cellceutix millions in trial costs

Also, the value of the strong Kevetrin patent (written by Dr Paul Ginsberg, the man who wrote the Claritin patent) literally covers tens of thousands of possible future chemical combinations for new drugs; a potentially very valuable proposition for multiple drug development

The CEO understands very well the potential value of Kevetrin, and has openly stated that he will not be interested in a buy out until Kevetrin has been advanced through trials far enough to generate maximum buyout value and shareholder ROI

Bottom Line : Kevetrin has the potential to become the standard next generation broad spectrum cancer treatment, and in doing so can provide transformational profits to investors that invest in the company before any further major developments

Prurisol Summary:

Prurisol is a compound that can be administered orally as a standard of care treatment for advanced psoriasis

Cellceutix is also working on starting an FDA fast tracked phase 2/3 trial for Prurisol, with Dr Reddy’s Labs in India currently undertaking production of the compound for upcoming trials

The compound has shown dramatic results so far in lab studies, and research showed Prurisol to be much more effective than methotrexate, a standard of care treatment for advanced psoriasis, as there was no recurrence of psoriasis on the animals

Here is a very good seeking alpha article that gives a good rundown of the potential of Kevetrin:

http://seekingalpha.com/article/309676-cellce...eakthrough


Also, a very influential technology analyst, Patrick Cox from Agora Financial, just issued a buy recommendation for CTIX to all his subscribers (he runs an $800/month newsletter on breakthrough technology stocks) He is well known in the investing community for having a talent in finding the greatest and most profound breakthrough technologies and medicines of our time, and CTIX has gotten his attention and close personal review.


Here is an article Mr Cox posted last year that gives good insight into why he beleives this will be the next huge biotech breakthrough in cancer treatments:



Calling on Guardian Angels to Fight Cancer
By Patrick Cox | April 14, 2011 |

In this month’s issue, I have a very exciting company for you. Although the company is very early-stage, with no human clinical data yet, I believe the science is sound. This company has discovered a compound that modifies a well-studied cellular process implicated in a broad range of cancers. For many years, it has been a holy grail of cancer researchers.

Tens, if not hundreds, of millions of dollars have been spent by pharmaceutical companies in the quest to find a therapy to hit this molecular target — but in vain. The tiny biotech we’re presenting this month, however, truly appears to have discovered the compound that does so successfully.

Obviously, preclinical biotechnology innovators make for more speculative investments than those that have reached the stage of clinical trials. With greater risk, however, also comes the potential for greater reward. The biggest yields in pharmaceuticals come from picking winners before human data verify the safety and efficacy of a drug in humans. Of course, the flip side of that coin is the possibility that clinical trials will fail.

Most investors and analysts, therefore, tend to rely solely on human clinical studies as the only means of judging a drug candidate. This is simply because most people lack the time, background or confidence to study and grasp the core scientific platforms of preclinical companies. This creates opportunities for investors who are willing to do their homework and buy into companies before clinical results drive share prices up.

Fortunately, we’re not living in the 20th century anymore. With Google Scholar and a little patience, you can instantaneously access information that could be found only in large university libraries just a few decades ago.

So I would like to tell you about a number of factors that indicate this company’s pipeline has transformational potential. Beyond the core science, which I’ll describe below, there is also the reputation and decades of experience of its founder and chief scientist. Additionally, strong preclinical data and outside interest lead me to believe the probability of success justifies adding this company to your watch list of transformational technologies. However, I encourage you to consider this technology carefully.

P53, The Guardian Angel of the Genome
Before addressing the company, though, I would like to talk about cancer and the “guardian angel gene.” Known to geneticists as TP53, this gene encodes the transcription factor p53. Lately, you’ve been hearing the term “transcription factor” in this publication quite a lot. There’s a reason for that. As the human genome and the proteins expressed by genes are understood, more and more breakthroughs will be enabled.

When this protein was discovered in 1979, the tools did not exist to fully analyze and understand the TP53 gene or its protein transcription factor p53. The scientific community assumed, in fact, that p53 was causing cancers. Later research revealed a much more complex and interesting story.

P53 is, in fact, a cancer-suppressing transcription factor, rather than a cancer-causing one. After discoveries revealed its role in preventing cancers, the journal Science named p53 “Molecule of the Year” for 1993.

Additional discoveries are still being made about p53. This protein clearly operates as a transcription factor, controlling the conversion of DNA information to messenger RNA, or mRNA. It also, however, seems to act in a pharmacological manner. Regardless, p53 plays an extremely important role in guarding cell health.

Specifically, p53 monitors the DNA and activates cellular gene repair processes when a cell sustains genetic damage. If genetic damage proves too extensive for repair, p53 triggers the cell’s built-in self-destruct process, apoptosis.

For this reason, the p53 protein has been called the master watchman of the genome. As such, it prevents the mutations that turn healthy cells into cancer cells.

There is an Achilles’ heel to this process, however. If the p53-encoding gene, TP53, itself receives damage, there is no mechanism to repair it as p53 repairs other genes. Its tumor-suppressing functionality is curtailed. Similarly, if some other factor interferes with p53's normal functioning, the TP53 gene can no longer prevent cancers.

This is the reason that human papillomavirus (HPV) leads to an increased risk of cancer. When HPV infects a cell, it causes it to manufacture a protein that binds to p53, inactivating the master watchman. For some cancers, such as cervical cancers, HPV is believed responsible for 70% of cases.

In more than half of all human cancers, p53 is suppressed by mutations of the TP53 gene itself. The other cancers directly inhibit p53's molecular signaling pathway. P53 suppression, therefore, is implicated in almost all cancers. If some molecule could restore p53's activity in cancer cells, it is believed that the cancers would be naturally and nontoxically eliminated. Such a molecule would be a powerful new oncology drug. This is exactly what this month’s watch list company, Beverly, Mass.-based Cellceutix (PINK SHEETS: CTIX), has discovered.

In preparing this issue, my associate Ray Blanco and I had the pleasure of interviewing Dr. Krishna Menon, Cellceutix’s president and chief scientific officer, as well as Leo Ehrlich, CEO and CFO.

Important Scientist at the Helm
I have, by the way, been familiar with the work of Dr. Menon and Leo Ehrlich for quite some time. In addition to being the founder of Cellceutix, Dr. Menon is the chief regulatory officer for one of the most exciting companies in our portfolio, NanoViricides (OTCBB: NNVC). Formerly, Ehrlich helped found NanoViricides and served as its CFO. Dr. Menon also runs KARD Scientific, a contract research organization (CRO). KARD Scientific has been instrumental in testing and developing NanoViricides’ breakthrough antiviral nanovesicle technology.

CROs are an important and growing part of the drug discovery process. Because they specialize in performing tests and validation, pharmaceutical and biotech companies have found advantages and saving by outsourcing various aspects of the research process to these important organizations.

Pharmas have increasingly turned to CROs as a way to cut costs and manage the complexity of bringing new products to market. Since 2002, KARD Scientific has successfully helped its clients file eight investigative new drug applications with the FDA, thus launching them into human clinical trials.

Researchers at CRO facilities, therefore, see a wide range of platform technologies and candidate compounds from all over the industry. For CRO researchers, exposure to a large variety of different drug candidates can lead to a uniquely broad biotech perspective and expertise. As the head of his own CRO, Dr. Menon has been in the position to develop a very good sense of what will eventually make it to market and what won’t.

Dr. Menon, who has been described as a “lab workaholic,” also has decades of his own experience developing important anti-cancer compounds. His Ph.D. work, for example, laid the foundation for Eli Lilly’s blockbuster cancer drug Alimta. He was also a key developer for Gemzar, another billion-dollar cancer drug. For this and other contributions, he was honored with Eli Lilly’s President’s Award in 1999.

Therefore, his confidence in Cellceutix’s leading candidate, a first-in-class p53-activating cancer compound, has considerable significance. The genesis of the compound, in fact, has roots reaching back many years in Dr. Menon’s long professional career.

As a young man, before earning graduate degrees in medicine and pharmacology, Dr. Menon was the chief veterinarian for a Jamaican parish, which is comparable to an American state. On one occasion, he was called to do a postmortem analysis following the mysterious death of an expensive prize bull. The investigation revealed that the animal had been treated with an agent designed to kill external parasites, a common problem in tropical countries.

During the postmortem analysis, Dr. Menon discovered that the tick-and-mite-killing product acted as a cytotoxic agent, causing organ failure. More importantly, however, he also observed that the bull had suffered from subcutaneous tumors, but many had been eliminated by the product.

The event marked the beginning of his quest to develop anti-cancer compounds that combine low toxicity with high efficacy. This theme has marked much of his career, and has already led to the creation of breakthrough cancer drugs. It is now reaching its culmination in Cellceutix’s leading compound, called Kevetrin.

Kevetrin, a Potential P53-Activating Blockbuster
Discovered by Dr. Menon, Kevetrin is a pharmaceutical-grade salt of a molecule belonging to a class of chemicals known as thioureal compounds. Though widely used in industrial chemical processes, this class of compounds has never before been considered a promising source of drug candidates. The compound on which Kevetrin is based has been used for some time as a chemical intermediary for synthesizing more complex compounds. Before Menon began looking at it, however, its potential as a therapeutic drug was never considered.

Originally, Kevetrin was considered by Cellceutix’s scientific team to be a very interesting candidate for treating head and neck cancers. Follow-up research conducted at Boston’s Dana-Farber Cancer Institute revealed that it had a much broader potential, however.

Further tests performed on cancer-resistant cell lines grown in animal models revealed astonishing results. Tumor growth was delayed in many different kinds of cancers. In many cases, tumor shrinkage was observed. Seeking independent verification, Cellceutix sent its compound to bioscience giant Millipore. Millipore’s screening panels revealed strong data for Kevetrin in cancers ranging from leukemia to solid tumors.

Some published efficacy data follows below. These two charts were presented at the 102nd annual meeting of the American Association for Cancer Research in early April 2011. Both of these charts compare Kevetrin to one of the most common chemotherapy drugs, paclitaxel. Both are xenografts grown in mice. The first chart is for lung cancer tumor line A549:

In the A549 mouse model, Kevetrin delayed tumor growth by 33–100% compared to paclitaxel. It caused only a 3–4% decrease in animal weight, which is a proxy for toxicity in mice.

The second chart below is for a drug-resistant lung cancer tumor cell line, NCI-H1975:

Here, Kevetrin showed a 44–107% delay in tumor growth compared to paclitaxel, and there was no reduction in animal weight, indicating that the compound was not producing negative metabolic effects.

As you can see, Kevetrin compares very, very favorably against paclitaxel. Similar results are observed in leukemias and cancers of the colon and breast.

Most late-stage cancers, by the way, are those that have become resistant to the current arsenal of anti-cancer drugs. Cancer cells are extremely resilient, behaving almost as autonomous organisms. They have the ability to modify and adapt to their environment through spontaneous mutation. An investigational compound showing such strong results in so many different varieties of resistant cancers is a truly big deal. Kevetrin has the potential to be a mega blockbuster. Most of the new cancer drugs on the market treat specific kinds of cancers. Kevetrin has the potential to treat many of them. This is an enormous, multibillion-dollar market.

As you can well guess, such wide-ranging efficacy prompted questions about Kevetrin’s mechanism of action and led to further experimentation. Research into Kevetrin’s mechanism of action revealed that it acts on p53 and additional pathways, interrupting cancer progression by restoring normal cancer-fighting mechanisms. Essentially, Kevetrin re-awakens the “guardian angel” of the genome and causes apoptosis in cancer cells:




As I mentioned earlier, the discovery of p53's importance in cancers has prompted Big Pharma to spend untold millions trying to therapeutically activate the transcription factor. Their research, however, has been concentrated in a different class of compounds known as nutlins. Some are promising p53 activators, but unfortunately, all nutlin-based compounds have demonstrated unacceptably high levels of toxicity.

This has not been the case for Kevetrin. Toxicology studies completed this March by Toxicon, another third-party CRO, revealed a very benign profile. This clears the way for an investigational new drug application (IND) with the FDA and human clinical trials.

The Kevetrin Game Plan
The next logical step for Kevetrin is to file an IND with the FDA for Phase I clinical trials. As you know, Phase I trials are typically performed on healthy patients with the goal of establishing a drug’s safety. If a candidate compound passes this milestone, it can move on to Phase II, where efficacy becomes the major focus.

Because Cellceutix is seeking approval for the use of Kevetrin in late-stage drug-resistant cancers, it will likely be safety tested on people who have a life-ending form of the disease. Therefore, Kevetrin has the unusual opportunity to demonstrate not only safety in Phase I, but efficacy.

Since Kevetrin has reported strong performance on drug-resistant cancers in preclinical research, its Phase I trials will probably be performed on a population of very sick, end-stage cancer patients. For these patients, there isn’t much hope with existing therapies, so there is little to lose and much to potentially gain by using Kevetrin.

Cellceutix will have an early opportunity to demonstrate the healing power of Kevetrin. In fact, if the Phase I results are strong enough, there is even a chance that Kevetrin could skip Phase II and go directly to Phase III. The FDA has programs in place, like Fast Track, Accelerated Approval and Priority Review, to expedite new drugs that have shown the potential to satisfy large unmet needs. An effective therapy for drug-resistant cancers would almost certainly qualify.

Cellceutix is gearing up for the Kevetrin IND application now. It is already in the advanced stages of preparing the application for the FDA. Leo Ehrlich expects Cellceutix to be able to file in early May, once quality control documentation for Kevetrin production is completed.

If there are no objections on the part of the FDA, the plan is to apply to begin clinical trials at Dana-Farber Cancer Institute this summer, where Dr. Menon has extensive contacts. Dr. Emil Frei, a member of Cellceutix’s scientific advisory board, is currently emeritus physician-in-chief at this institution.

For a small biotech company like Cellceutix, a winning game plan usually involves collaboration with a large, deep-pocketed pharmaceutical company to help fund the clinical trials process. On the other side of that equation, the pharmaceutical companies have to collaborate to survive. Flagging in-house pipelines and expiring patent protections demand that they look to emerging biotechs for the next big products.

As a general rule, Big Pharmas express little interest in a compound until human data are released in Phase I or later studies. Kevetrin is an exception to this rule. Already, several big players have expressed interest, and one multibillion-dollar drug maker has even signed a nondisclosure agreement based on the strength of the preclinical data.

Ehrlich, however, tells us that Cellceutix is in no hurry to partner until the company is in a stronger position. While some investors might hope for an early Big Pharma deal, yields are maximized by taking drug candidates through the clinical trials process. This reduces risk for pharmas and increases competition among them for a partnership agreement. Phase I trials are usually the smallest and least expensive to run, and Ehrlich believes the company has the financial strength to carry it out on its own. This is good news for Cellceutix investors.

Kevetrin also has a strong intellectual property position. In the biotechnology business, strong patent protections are often the difference between success and failure. The patent for Kevetrin was published last year, and was written by Dr. Paul Ginsburg. Dr. Ginsburg, a patent attorney, has worked in senior positions at Pfizer and Schering. Among other important pharmaceutical patents, he wrote Claritin’s. It has never been challenged.

Moreover, because this class of chemicals has never been used in medicine, research into other pharmaceutical uses has barely begun. The number of potential uses is, in fact, vast. Cellceutix’s patent covers tens of thousands of possible chemical combinations for therapeutic use.

Growing Preclinical Pipeline
As promising as Kevetrin is, Cellceutix has other compounds with enormous potential waiting in the wings. Among those compounds is KM-391, which is targeted at autism.

As you know, autism is an enormous problem. In children with autism, there is a loss of brain function due to reduced brain plasticity and serotonin depletion. This, in turn, leads to various cognitive and behavioral disorders.

About 1% of the population between the ages of 3–17 is diagnosed with autism spectrum disorder. The total annual cost for autism in the United States is estimated at $60 billion, but only 5% of private research funding targets autism. Everything that is currently approved for treatment of autism addresses only symptoms, rather than the root causes.

As former director for the ALS foundation, Dr. Menon has considerable experience with neurological diseases. When he came across KM-391, originally developed in India, he saw its value and purchased the rights. He also improved the original compound.

Preclinical tests, performed in autism animal models, indicate no apparent side effects from long-term administration of KM-391. Measures of efficacy, however, are very strong. One hundred days into KM-391 trials, brain plasticity showed an 85% improvement over control in rats. Plasticity, as you know, refers to the brain’s ability to adapt to changes. Additionally, brain serotonin increased to normal levels when compared to a healthy pair-matched animal’s:

Rats treated with KM-391 also showed improvements in tests for autism-related behavioral disorders. There were marked reductions in repetitive behavior, touch sensitivity and self-induced injury, as well as improvements in group dynamics, position correction time and curiosity.

Cellceutix is preparing to file an IND for KM-391. As a small biotech with limited resources, however, Cellceutix has to concentrate on its leading compound. A successful IND and Phase I for Kevetrin will clear the path for KM-391. If KM-391 shows positive results in humans, it could completely change the way autism is treated. Like Kevetrin, this compound has multibillion-dollar potential.

Cellceutix has other candidates in its pipeline. It has preclinical and developmental-stage compounds for the treatment of psoriasis, arthritis, asthma, ALS, cancer and hypertension.

As I mentioned earlier, preclinical companies are inherently more speculative than later-stage companies, but they also have the opportunity for much greater share price appreciation. Cellceutix has a lead candidate that could be a game changer in cancer treatment. It has a world-class scientist leading research and a CEO with experience in launching new biotechnology companies. The company plans to collaborate on its candidates when it becomes appropriate, and has attracted considerable interest at an early stage based on the strength of its data.

That being said, this company is far too small for us to recommend purchasing at this time. The exciting potential of their science, however, is something I will be keeping a close watch on.

This is the most illiquid stock we have ever discussed here. If you decide to buy at this time, you are on your own — but I would encourage you to be very careful and use a strict limit order.

In the mean time, I am going to add this company to our watch list. When it is time to issue an official buy order, you will be the first to know.



As i mentioned, this article was before he posted a buy recommendation, which had just become official in September 2012.



It is my humble belief, that this company, now trading around $1 per share, will be valuated with an over 10 billion dollar market cap, and will return at least a 4000%-5000% return on investment in the next 12-18 months, when a huge buyout takes place from a major pharmaceutical player, such as Roche or Pfizer.