This is also speculating that by adding an additio
Post# of 5066
Quote:
Indeed the possibility of amplifying such tolerogenic loops by administration
of agents that increase the number of Treg cells, which has previously been clinically applied
using non-Fc binding antiCD3 [45], may be assessed in future experiments to augment the
tolerogenic process.
In conclusion, the current paper provides proof of concept for the utilization of siRNA in
modifying recipient responses to allogeneic transplantation. The possibility of inhibiting
chronic rejection through targeting the indirect pathway of antigen presentation suggests a
possibility to overcome limitations of current immune suppressants.