Anavex Life Sciences (AVXL) 0.3010 $AVXL
Inflammatory Pain - Pipeline Review, H1 2014: 43 Company and 68 Drug Profiled
M2 - Wed May 07, 8:49AM CDT
Research and Markets (http://www.researchandmarkets.com/research/zxzwlh/inflammatory_pain) has announced the addition of the "Inflammatory Pain - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for Inflammatory Pain, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Inflammatory Pain and special features on late-stage and discontinued projects. The report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Companies Involved: - A2M Pharma GmbH - AbbVie Inc. - Adynxx, Inc. - AnaMar AB - Anavex Life Sciences Corp. - AngioChem Inc. - Aniona ApS - Array BioPharma Inc. - Asahi Kasei Pharma Corp. - AskAt Inc. - AstraZeneca PLC - Biousian Biosystems, Inc. - Boehringer Ingelheim GmbH - CLL Pharma - DiverDrugs, S.L. - Evotec AG - Glenmark Pharmaceuticals Ltd. - Grunenthal GmbH - Hydra Biosciences, Inc. - RaQualia Pharma Inc. - Relevare Pharmaceuticals Ltd. - Shionogi & Co., Ltd. - Sunovion Pharmaceuticals Inc. - Takeda Pharmaceutical Company Limited - Theralpha SAS - Upsher-Smith Laboratories, Inc. - Winston Pharmaceuticals, Inc. - Zalicus Inc. - Ziarco Pharma Ltd Drug Profiles: - minocycline - grapiprant - AN-721 - ZPL-3893787 - Z-944 - lidocaine - S-120083 - SYN-1002 - Small Molecule To Antagonise P2X3 and P2X2/3 - OX-MPI - nNOS/iNOS - HC-030031 - zucapsaicin - TrkA Program - ANAVEX-1079 - ANG-2002 - AMAP-102 - RQ-00000008 - GBR-900 - CDK9 Inhibitors - Neu-P12 - CNSB-002 - CNSB-006 - AK-106 - Z-212 - PLX Cells For Neuropathic And Inflammatory Pain - THA-902 - Conolidine - AYX-3 - Project MITRA For more information visit http://www.researchandmarkets.com/research/zx...atory_pain
Epilepsy - Pipeline Review, H1 2014: 43 Companies and 97 Drugs Profiled
M2 - Wed May 07, 8:38AM CDT
Research and Markets (http://www.researchandmarkets.com/research/652dzz/epilepsy) has announced the addition of the "Epilepsy - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for Epilepsy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Epilepsy and special features on late-stage and discontinued projects. The report features investigatory drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. Companies Involved: - Acorda Therapeutics, Inc. - Advicenne Pharma - Aeolus Pharmaceuticals, Inc. - Aestus Therapeutics, Inc. - Allergan, Inc. - Anavex Life Sciences Corp. - Aniona ApS - Asklepios BioPharmaceutical, Inc. - Astellas Pharma Inc. - Bial - Portela & Ca, S.A. - Bio-Link Australia Pty. Ltd. - BioCrea GmbH - Bionomics Limited - Biovista Inc. - Celentyx Ltd. - Chong Kun Dang Pharmaceutical Corp. - Concert Pharmaceuticals, Inc. - Convergence Pharmaceuticals Ltd. - D-Pharm Ltd. - Eisai Co., Ltd. - GW Pharmaceuticals plc - Glialogix, Inc. - Sun Pharmaceutical Industries Limited - UCB S.A. - Upsher-Smith Laboratories, Inc. - Vertex Pharmaceuticals Incorporated - Vichem Chemie Research Ltd. - XERIS Pharmaceuticals, Inc. - Zalicus Inc. Drug Profiles: - lacosamide - perampanel - eslicarbazepine acetate - diazepam - ADV-5803 - lacosamide - brivaracetam - carbamazepine - carisbamate - diazepam - eslicarbazepine acetate - lacosamide - everolimus - belnacasan - YKP-3089 - naluzotan - DP-VPA - selurampanel - ganaxolone - IPX-218 - topiramate - tonabersat - GWP-42006 - SUN-44 - INS-001 - PF-04895162 - CKD-903 - ANAVEX-2-73 - Antiepileptic Drugs - ANAVEX-19-144 For more information visit http://www.researchandmarkets.com/research/652dzz/epilepsy
Anavex Encouraged by Scientific Data Confirming Sigma-1 Receptor Agonist is Potentially Disease-Modifying in Parkinson's Disease
GlobeNewswire - Tue Apr 29, 6:27AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, other diseases of the central nervous system (CNS) and various types of cancer, today announced the findings of a research study published in the current issue of peer-reviewed scientific journal Brain. For the first time, scientific data shows that a sigma-1 receptor (S1R) agonist produces functional neurorestoration in animal models of Parkinson's disease (PD). Anavex is encouraged by the report because its results point to the potential for the Company's S1R drug candidates ANAVEX 2-73, ANAVEX 3-71 (AF710B) and ANAVEX 1-41 of being disease-modifying treatments for Parkinson's disease.
Anavex Strengthens Alzheimer's Pipeline, Obtains Exclusive Worldwide Rights to Intellectual Property
GlobeNewswire - Mon Mar 31, 7:15AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has strengthened its Alzheimer's pipeline by obtaining exclusive rights to worldwide patents and patent applications covering methods and compositions for AF710B and other related, preclinical stage compounds from Life Science Research Israel Ltd. (LSRI). LSRI has a proven track record of successfully developing and bringing drugs to market. The licensing of AF710B complements Anavex's existing pipeline in Alzheimer's disease, which is the company's core competency and includes lead clinical candidate ANAVEX PLUS.
Anavex Reports Predicted Clinical Effect of Both ANAVEX 2-73 and ANAVEX PLUS in a Humanized Cortical Cognitive Model for Alzheimer's Disease
GlobeNewswire - Thu Mar 27, 12:00PM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, today announced that a report in the current issue of peer-reviewed International Pharmaceutical Industry Journal ("IPI Journal" predicts that ANAVEX 2-73 will have a meaningful effect in Alzheimer's disease based on the Alzheimer's Disease Assessment Scale-Cognitive ("ADAS-Cog" , especially when combined with donepezil (Aricept(R)), the world's best-selling Alzheimer's drug. The Company believes this drug combination, called ANAVEX PLUS, is a compelling commercial opportunity because of its potential to treat symptoms of Alzheimer's while also possibly modifying or reversing the course of the disease. A Phase 1b/2a clinical trial of ANAVEX PLUS, is scheduled to begin mid 2014.
Anavex Successfully Closes $10 Million Financing to Initiate Phase 1b/2a Alzheimer's Clinical Trial
GlobeNewswire - Wed Mar 19, 6:37AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has closed, as previously announced on March 13, 2014, the private placement of $10 million in principal amount of convertible debentures with several institutional and accredited investors, including U.S. and international healthcare funds. In addition, the investors received warrants to purchase up to approximately 66.7 million shares of common stock in the aggregate.
Anavex Life Sciences signs USD10m private placement to execute clinical trial Phase 1b/2a in Alzheimer's and advance product portfolio
M2 - Fri Mar 14, 4:01AM CDT
Biopharmaceutical company Anavex Life Sciences (Other OTC:AVXL) said on Thursday that it has signed a private placement of USD10m of convertible debentures with several institutional and accredited investors, including US and international healthcare funds,.
Anavex Announces $10 Million Private Placement of Convertible Debentures
GlobeNewswire - Thu Mar 13, 9:36AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has entered into definitive agreements with several institutional and accredited investors, including U.S. and international healthcare funds, for a private placement of approximately $10 million in principal amount of convertible debentures. In addition, the investors will receive warrants to purchase up to approximately 66.7 million shares of common stock in the aggregate.
Anavex Encouraged By Scientific Data Confirming Sigma-1 Receptor Agonist Extends Survival in ALS (Lou Gehrig's Disease)
GlobeNewswire - Mon Mar 10, 6:39AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, today announced the findings of a research report published in the current issue of peer-reviewed scientific journal Neuroscience Letters. The Company is encouraged by the report because its results point to potential for ANAVEX 2-73 to treat ALS, also known as Lou Gehrig's disease. Data showed that sigma-1 receptor (S1R) agonists are effective in suppressing motor neuron degeneration and symptom progression in ALS animal models.
Anavex: Research Report Reveals Cardioprotective Action of Sigma-1 Receptor Agonists
GlobeNewswire - Tue Mar 04, 6:33AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) is encouraged by the findings of a research report published in the current issue of peer-reviewed scientific journal Life Sciences. Among its conclusions, the report reveals that sigma-1 receptor (S1R) agonists play an important role in the prevention, delay or reduction of heart disease. These findings correlate with the positive electrocardiogram (EKG) parameters in the successfully completed human clinical Phase 1 safety trial of ANAVEX 2-73, an orally available S1R agonist drug candidate developed to treat Alzheimer's through potential disease modification. ANAVEX 2-73 has also shown highly encouraging synergy with donepezil, the world's best-selling Alzheimer's drug, and a Phase 1b/2a clinical trial of this combination, ANAVEX PLUS, is planned for the first half of 2014.
Research Report Confirms Opportunity for Anavex Anti-Cancer and Neuropathic Pain Compounds
GlobeNewswire - Wed Feb 26, 7:42AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced that a research article in the current issue of peer-reviewed scientific journal Molecular Pain reveals a new opportunity for the Company's anti-cancer and neuropathic pain compounds. The article describes that sigma-1 receptor (S1R) modulation prevents neuropathic pain and mitochondrial abnormalities induced by the chemotherapy drug paclitaxel.
Anavex to Present at 16th Annual BIO CEO & Investor Conference
GlobeNewswire - Mon Feb 03, 6:27AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced that Christopher U. Missling, PhD, President and Chief Executive Officer, will be presenting at the 16th Annual BIO CEO & Investor Conference on Monday, February 10, 2014, at 1:00 p.m. ET in the Conrad Room. The conference will be held at the Waldorf-Astoria Hotel in New York, NY.
Sigma-1 receptor Implicated in Cell Survival of Rare Neurodegenerative Diseases - Expanding the Opportunity for Application of ANAVEX PLUS in Rare Diseases
GlobeNewswire - Thu Jan 23, 6:17AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced that a publication in the current issue of scientific journal Neuropathology potentially extends the opportunity for ANAVEX PLUS to additional neurodegenerative diseases beyond Alzheimer's.
Anavex Agreement With The Roskamp Institute to Advance the Clinical Development of ANAVEX PLUS
GlobeNewswire - Tue Jan 14, 4:15PM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced that they have established an agreement with The Roskamp Institute for the clinical development of ANAVEX PLUS, a new combination drug of ANAVEX 2-73 and donepezil (Aricept(R)) for the treatment of Alzheimer's disease. This study will evaluate the safety, tolerability, pharmacokinetics, and possible clinical benefits of ANAVEX PLUS in Alzheimer's disease patients and other diseases associated with dementia and cognitive impairment.
Anavex CEO Invited to Present at Upcoming Investment Conferences
GlobeNewswire - Tue Jan 07, 7:11AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced that its President and Chief Executive Officer Christopher U. Missling, PhD, will participate in the 7 Annual OneMedForum: Investing in Healthcare 2014 ("OneMedForum" and the Noble Financial Capital Markets ("Noble" Tenth Annual Equity Conference.
Anavex Life Sciences Corp elects John Harrison to Scientific Advisory Board
M2 - Wed Dec 11, 4:18AM CST
Biopharmaceutical company Anavex Life Sciences Corp (OTC Markets:AVXL) revealed on Tuesday the election of John Harrison, PhD, to its Scientific Advisory Board.
Anavex Appoints Clinical Design Expert to Scientific Advisory Board
GlobeNewswire - Tue Dec 10, 7:10AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company" (OTCQB:AVXL) today announced the appointment of John Harrison, PhD, to its Scientific Advisory Board. Dr. Harrison is an internationally acknowledged specialist for design of human clinical outcome measurement in Alzheimer's disease and other cognitive impairments.
Market Research: Depression - Pipeline Review, H2 2013
M2 - Fri Dec 06, 3:43AM CST
Research and Markets (http://www.researchandmarkets.com/research/q2dd65/depression) has announced the addition of the "Depression - Pipeline Review, H2 2013" report to their offering. 'Depression - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Depression, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Depression. Scope - A snapshot of the global therapeutic scenario for Depression. - A review of the Depression products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Depression pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Mentioned Bristol-Myers Squibb Company Johnson & Johnson Boehringer Ingelheim GmbH AstraZeneca PLC GlaxoSmithKline plc Daiichi Sankyo Company, Ltd Taisho Pharmaceutical Co., Ltd. Takeda Pharmaceutical Company Limited Neurocrine Biosciences, Inc. Aphios Corporation Eisai Co., Ltd. H Lundbeck A/S Mitsubishi Tanabe Pharma Corporation Pfizer Inc. Sigma-Tau S.p.A. Addex Pharmaceuticals FAES Farma SA Anavex Life Sciences Corp. Karo Bio KunWha Pharmaceutical Co., Ltd. Newron Pharmaceuticals S.p.A. M et P Pharma AG Angelini Group Domain Therapeutics For more information visit http://www.researchandmarkets.com/research/q2dd65/depression About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.
Inflammatory Pain - Pipeline Review, H1 2014: 43 Company and 68 Drug Profiled
M2 - Wed May 07, 8:49AM CDT
Research and Markets (http://www.researchandmarkets.com/research/zxzwlh/inflammatory_pain) has announced the addition of the "Inflammatory Pain - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for Inflammatory Pain, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Inflammatory Pain and special features on late-stage and discontinued projects. The report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Companies Involved: - A2M Pharma GmbH - AbbVie Inc. - Adynxx, Inc. - AnaMar AB - Anavex Life Sciences Corp. - AngioChem Inc. - Aniona ApS - Array BioPharma Inc. - Asahi Kasei Pharma Corp. - AskAt Inc. - AstraZeneca PLC - Biousian Biosystems, Inc. - Boehringer Ingelheim GmbH - CLL Pharma - DiverDrugs, S.L. - Evotec AG - Glenmark Pharmaceuticals Ltd. - Grunenthal GmbH - Hydra Biosciences, Inc. - RaQualia Pharma Inc. - Relevare Pharmaceuticals Ltd. - Shionogi & Co., Ltd. - Sunovion Pharmaceuticals Inc. - Takeda Pharmaceutical Company Limited - Theralpha SAS - Upsher-Smith Laboratories, Inc. - Winston Pharmaceuticals, Inc. - Zalicus Inc. - Ziarco Pharma Ltd Drug Profiles: - minocycline - grapiprant - AN-721 - ZPL-3893787 - Z-944 - lidocaine - S-120083 - SYN-1002 - Small Molecule To Antagonise P2X3 and P2X2/3 - OX-MPI - nNOS/iNOS - HC-030031 - zucapsaicin - TrkA Program - ANAVEX-1079 - ANG-2002 - AMAP-102 - RQ-00000008 - GBR-900 - CDK9 Inhibitors - Neu-P12 - CNSB-002 - CNSB-006 - AK-106 - Z-212 - PLX Cells For Neuropathic And Inflammatory Pain - THA-902 - Conolidine - AYX-3 - Project MITRA For more information visit http://www.researchandmarkets.com/research/zx...atory_pain
Epilepsy - Pipeline Review, H1 2014: 43 Companies and 97 Drugs Profiled
M2 - Wed May 07, 8:38AM CDT
Research and Markets (http://www.researchandmarkets.com/research/652dzz/epilepsy) has announced the addition of the "Epilepsy - Pipeline Review, H1 2014" report to their offering. This report provides comprehensive information on the therapeutic development for Epilepsy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Epilepsy and special features on late-stage and discontinued projects. The report features investigatory drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. Companies Involved: - Acorda Therapeutics, Inc. - Advicenne Pharma - Aeolus Pharmaceuticals, Inc. - Aestus Therapeutics, Inc. - Allergan, Inc. - Anavex Life Sciences Corp. - Aniona ApS - Asklepios BioPharmaceutical, Inc. - Astellas Pharma Inc. - Bial - Portela & Ca, S.A. - Bio-Link Australia Pty. Ltd. - BioCrea GmbH - Bionomics Limited - Biovista Inc. - Celentyx Ltd. - Chong Kun Dang Pharmaceutical Corp. - Concert Pharmaceuticals, Inc. - Convergence Pharmaceuticals Ltd. - D-Pharm Ltd. - Eisai Co., Ltd. - GW Pharmaceuticals plc - Glialogix, Inc. - Sun Pharmaceutical Industries Limited - UCB S.A. - Upsher-Smith Laboratories, Inc. - Vertex Pharmaceuticals Incorporated - Vichem Chemie Research Ltd. - XERIS Pharmaceuticals, Inc. - Zalicus Inc. Drug Profiles: - lacosamide - perampanel - eslicarbazepine acetate - diazepam - ADV-5803 - lacosamide - brivaracetam - carbamazepine - carisbamate - diazepam - eslicarbazepine acetate - lacosamide - everolimus - belnacasan - YKP-3089 - naluzotan - DP-VPA - selurampanel - ganaxolone - IPX-218 - topiramate - tonabersat - GWP-42006 - SUN-44 - INS-001 - PF-04895162 - CKD-903 - ANAVEX-2-73 - Antiepileptic Drugs - ANAVEX-19-144 For more information visit http://www.researchandmarkets.com/research/652dzz/epilepsy
Anavex Encouraged by Scientific Data Confirming Sigma-1 Receptor Agonist is Potentially Disease-Modifying in Parkinson's Disease
GlobeNewswire - Tue Apr 29, 6:27AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, other diseases of the central nervous system (CNS) and various types of cancer, today announced the findings of a research study published in the current issue of peer-reviewed scientific journal Brain. For the first time, scientific data shows that a sigma-1 receptor (S1R) agonist produces functional neurorestoration in animal models of Parkinson's disease (PD). Anavex is encouraged by the report because its results point to the potential for the Company's S1R drug candidates ANAVEX 2-73, ANAVEX 3-71 (AF710B) and ANAVEX 1-41 of being disease-modifying treatments for Parkinson's disease. Anavex Strengthens Alzheimer's Pipeline, Obtains Exclusive Worldwide Rights to Intellectual Property
GlobeNewswire - Mon Mar 31, 7:15AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has strengthened its Alzheimer's pipeline by obtaining exclusive rights to worldwide patents and patent applications covering methods and compositions for AF710B and other related, preclinical stage compounds from Life Science Research Israel Ltd. (LSRI). LSRI has a proven track record of successfully developing and bringing drugs to market. The licensing of AF710B complements Anavex's existing pipeline in Alzheimer's disease, which is the company's core competency and includes lead clinical candidate ANAVEX PLUS. Anavex Reports Predicted Clinical Effect of Both ANAVEX 2-73 and ANAVEX PLUS in a Humanized Cortical Cognitive Model for Alzheimer's Disease
GlobeNewswire - Thu Mar 27, 12:00PM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, today announced that a report in the current issue of peer-reviewed International Pharmaceutical Industry Journal ("IPI Journal" predicts that ANAVEX 2-73 will have a meaningful effect in Alzheimer's disease based on the Alzheimer's Disease Assessment Scale-Cognitive ("ADAS-Cog" , especially when combined with donepezil (Aricept(R)), the world's best-selling Alzheimer's drug. The Company believes this drug combination, called ANAVEX PLUS, is a compelling commercial opportunity because of its potential to treat symptoms of Alzheimer's while also possibly modifying or reversing the course of the disease. A Phase 1b/2a clinical trial of ANAVEX PLUS, is scheduled to begin mid 2014. Anavex Successfully Closes $10 Million Financing to Initiate Phase 1b/2a Alzheimer's Clinical Trial
GlobeNewswire - Wed Mar 19, 6:37AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has closed, as previously announced on March 13, 2014, the private placement of $10 million in principal amount of convertible debentures with several institutional and accredited investors, including U.S. and international healthcare funds. In addition, the investors received warrants to purchase up to approximately 66.7 million shares of common stock in the aggregate. Anavex Life Sciences signs USD10m private placement to execute clinical trial Phase 1b/2a in Alzheimer's and advance product portfolio
M2 - Fri Mar 14, 4:01AM CDT
Biopharmaceutical company Anavex Life Sciences (Other OTC:AVXL) said on Thursday that it has signed a private placement of USD10m of convertible debentures with several institutional and accredited investors, including US and international healthcare funds,.
Anavex Announces $10 Million Private Placement of Convertible Debentures
GlobeNewswire - Thu Mar 13, 9:36AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, announced today that it has entered into definitive agreements with several institutional and accredited investors, including U.S. and international healthcare funds, for a private placement of approximately $10 million in principal amount of convertible debentures. In addition, the investors will receive warrants to purchase up to approximately 66.7 million shares of common stock in the aggregate. Anavex Encouraged By Scientific Data Confirming Sigma-1 Receptor Agonist Extends Survival in ALS (Lou Gehrig's Disease)
GlobeNewswire - Mon Mar 10, 6:39AM CDT
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL), a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer's, diseases of the central nervous system (CNS) and various types of cancer, today announced the findings of a research report published in the current issue of peer-reviewed scientific journal Neuroscience Letters. The Company is encouraged by the report because its results point to potential for ANAVEX 2-73 to treat ALS, also known as Lou Gehrig's disease. Data showed that sigma-1 receptor (S1R) agonists are effective in suppressing motor neuron degeneration and symptom progression in ALS animal models. Anavex: Research Report Reveals Cardioprotective Action of Sigma-1 Receptor Agonists
GlobeNewswire - Tue Mar 04, 6:33AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) is encouraged by the findings of a research report published in the current issue of peer-reviewed scientific journal Life Sciences. Among its conclusions, the report reveals that sigma-1 receptor (S1R) agonists play an important role in the prevention, delay or reduction of heart disease. These findings correlate with the positive electrocardiogram (EKG) parameters in the successfully completed human clinical Phase 1 safety trial of ANAVEX 2-73, an orally available S1R agonist drug candidate developed to treat Alzheimer's through potential disease modification. ANAVEX 2-73 has also shown highly encouraging synergy with donepezil, the world's best-selling Alzheimer's drug, and a Phase 1b/2a clinical trial of this combination, ANAVEX PLUS, is planned for the first half of 2014. Research Report Confirms Opportunity for Anavex Anti-Cancer and Neuropathic Pain Compounds
GlobeNewswire - Wed Feb 26, 7:42AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced that a research article in the current issue of peer-reviewed scientific journal Molecular Pain reveals a new opportunity for the Company's anti-cancer and neuropathic pain compounds. The article describes that sigma-1 receptor (S1R) modulation prevents neuropathic pain and mitochondrial abnormalities induced by the chemotherapy drug paclitaxel. Anavex to Present at 16th Annual BIO CEO & Investor Conference
GlobeNewswire - Mon Feb 03, 6:27AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced that Christopher U. Missling, PhD, President and Chief Executive Officer, will be presenting at the 16th Annual BIO CEO & Investor Conference on Monday, February 10, 2014, at 1:00 p.m. ET in the Conrad Room. The conference will be held at the Waldorf-Astoria Hotel in New York, NY. Sigma-1 receptor Implicated in Cell Survival of Rare Neurodegenerative Diseases - Expanding the Opportunity for Application of ANAVEX PLUS in Rare Diseases
GlobeNewswire - Thu Jan 23, 6:17AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced that a publication in the current issue of scientific journal Neuropathology potentially extends the opportunity for ANAVEX PLUS to additional neurodegenerative diseases beyond Alzheimer's. Anavex Agreement With The Roskamp Institute to Advance the Clinical Development of ANAVEX PLUS
GlobeNewswire - Tue Jan 14, 4:15PM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced that they have established an agreement with The Roskamp Institute for the clinical development of ANAVEX PLUS, a new combination drug of ANAVEX 2-73 and donepezil (Aricept(R)) for the treatment of Alzheimer's disease. This study will evaluate the safety, tolerability, pharmacokinetics, and possible clinical benefits of ANAVEX PLUS in Alzheimer's disease patients and other diseases associated with dementia and cognitive impairment. Anavex CEO Invited to Present at Upcoming Investment Conferences
GlobeNewswire - Tue Jan 07, 7:11AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced that its President and Chief Executive Officer Christopher U. Missling, PhD, will participate in the 7 Annual OneMedForum: Investing in Healthcare 2014 ("OneMedForum" and the Noble Financial Capital Markets ("Noble" Tenth Annual Equity Conference. Anavex Life Sciences Corp elects John Harrison to Scientific Advisory Board
M2 - Wed Dec 11, 4:18AM CST
Biopharmaceutical company Anavex Life Sciences Corp (OTC Markets:AVXL) revealed on Tuesday the election of John Harrison, PhD, to its Scientific Advisory Board.
Anavex Appoints Clinical Design Expert to Scientific Advisory Board
GlobeNewswire - Tue Dec 10, 7:10AM CST
Anavex Life Sciences Corp. ("Anavex" or the "Company"
(OTCQB:AVXL) today announced the appointment of John Harrison, PhD, to its Scientific Advisory Board. Dr. Harrison is an internationally acknowledged specialist for design of human clinical outcome measurement in Alzheimer's disease and other cognitive impairments. Market Research: Depression - Pipeline Review, H2 2013
M2 - Fri Dec 06, 3:43AM CST
Research and Markets (http://www.researchandmarkets.com/research/q2dd65/depression) has announced the addition of the "Depression - Pipeline Review, H2 2013" report to their offering. 'Depression - Pipeline Review, H2 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Depression, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Depression. Scope - A snapshot of the global therapeutic scenario for Depression. - A review of the Depression products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Depression pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Companies Mentioned Bristol-Myers Squibb Company Johnson & Johnson Boehringer Ingelheim GmbH AstraZeneca PLC GlaxoSmithKline plc Daiichi Sankyo Company, Ltd Taisho Pharmaceutical Co., Ltd. Takeda Pharmaceutical Company Limited Neurocrine Biosciences, Inc. Aphios Corporation Eisai Co., Ltd. H Lundbeck A/S Mitsubishi Tanabe Pharma Corporation Pfizer Inc. Sigma-Tau S.p.A. Addex Pharmaceuticals FAES Farma SA Anavex Life Sciences Corp. Karo Bio KunWha Pharmaceutical Co., Ltd. Newron Pharmaceuticals S.p.A. M et P Pharma AG Angelini Group Domain Therapeutics For more information visit http://www.researchandmarkets.com/research/q2dd65/depression About Research and Markets Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.
