The non-psychoactive carboxylates (e.g., CBDA, THC
Post# of 36728
Posted On: 12/29/2013 12:20:37 AM
The non-psychoactive carboxylates (e.g., CBDA, THCA) are potent medicine in their own right and, because of that quality, are now the subject of particular interest to researchers.
Dharmanol, in addition to powerful CBD, also contains healthy amounts of mixed carboxylates .
Delta9-THCA possesses anti-inflammatory and anti-neurodegenerative properties. Delta9-THCA inhibits cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), in human colon cell cultures (Ruhaak et. al., 2011). COX-1 and COX-2 are both enzymes involved in inflammation. Delta9-THCA has also been shown to decrease the amount of oxidative stress caused by mitochondrial impairment, a major mechanism in neural degeneration, in mouse mesencephalic cell cultures (Moldzio et al., 2012).
http://www.aphios.com/products/research-chemi...-thca.html
THCA not only has anti-proliferative abilities that are crucial in helping inhibit the growth of cancerous cells, but also, it has anti-spasmodic abilities that helps subdue muscle spasms and therefore has potential use among epileptic patients
Recent research has shown CBDA, which has anti-inflammatory properties greater than THCA, to have powerful healing properties including management of schizophrenia. According to Dr. Mitch Earleywine, researchers at Harvard showed that CBDA makes breast cancer cells kill themselves and researchers in Japan found CBDA keeps breast cancer cells from spreading.
It was initially thought that cannabidiol’s (CBD) main function was to counter the psychoactive effects of THC, but more evidence seems to show that medically, CBD packs quite a punch on its own. It looks to be especially promising for conditions that are difficult to treat such as Crohn’s disease , PTSD and multiple sclerosis . Lately, it is one of the rarest of these conditions, Dravet’s Syndrome , that is getting a lot of attention from both the medical community and the public. Dravet’s Syndrome is an especially debilitating form of epilepsy that affects children and is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets and brain surgery, but all have mixed success rates.
For many patients, especially older patients, they are looking for a cannabis therapy option that doesn’t have a significant amount of psychoactivity, or feelings of being high, associated with use. Patients reporting on results of daily THC-acid and CBD-acid therapy generally note that their symptoms were alleviated with a few days to a couple of weeks of beginning daily ingestion of acidic cannabinoids. Many of the patients who have anecdotally reported successful results with this therapeutic approach suffer from chronic conditions such as ALS, autism, Fibromyalgia, Multiple Sclerosis as well as patients suffering from neuropathy, either induced by a condition such as HIV or from the use of certain drugs
Dharmanol, in addition to powerful CBD, also contains healthy amounts of mixed carboxylates .
Delta9-THCA possesses anti-inflammatory and anti-neurodegenerative properties. Delta9-THCA inhibits cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), in human colon cell cultures (Ruhaak et. al., 2011). COX-1 and COX-2 are both enzymes involved in inflammation. Delta9-THCA has also been shown to decrease the amount of oxidative stress caused by mitochondrial impairment, a major mechanism in neural degeneration, in mouse mesencephalic cell cultures (Moldzio et al., 2012).
http://www.aphios.com/products/research-chemi...-thca.html
THCA not only has anti-proliferative abilities that are crucial in helping inhibit the growth of cancerous cells, but also, it has anti-spasmodic abilities that helps subdue muscle spasms and therefore has potential use among epileptic patients
Recent research has shown CBDA, which has anti-inflammatory properties greater than THCA, to have powerful healing properties including management of schizophrenia. According to Dr. Mitch Earleywine, researchers at Harvard showed that CBDA makes breast cancer cells kill themselves and researchers in Japan found CBDA keeps breast cancer cells from spreading.
It was initially thought that cannabidiol’s (CBD) main function was to counter the psychoactive effects of THC, but more evidence seems to show that medically, CBD packs quite a punch on its own. It looks to be especially promising for conditions that are difficult to treat such as Crohn’s disease , PTSD and multiple sclerosis . Lately, it is one of the rarest of these conditions, Dravet’s Syndrome , that is getting a lot of attention from both the medical community and the public. Dravet’s Syndrome is an especially debilitating form of epilepsy that affects children and is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets and brain surgery, but all have mixed success rates.
For many patients, especially older patients, they are looking for a cannabis therapy option that doesn’t have a significant amount of psychoactivity, or feelings of being high, associated with use. Patients reporting on results of daily THC-acid and CBD-acid therapy generally note that their symptoms were alleviated with a few days to a couple of weeks of beginning daily ingestion of acidic cannabinoids. Many of the patients who have anecdotally reported successful results with this therapeutic approach suffer from chronic conditions such as ALS, autism, Fibromyalgia, Multiple Sclerosis as well as patients suffering from neuropathy, either induced by a condition such as HIV or from the use of certain drugs
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