Dharmanol discussion here has focused on non-psychoactive CBD and THCA as two powerful medicinal agents. Little has been said about CBDA. THCA and CBDA are both cannabinoid carboxylates. Dharmanol, with its CBD and "mixed cannabinoid carboxylates," would also contain CBDA.
We know that THC is the psychocactive delta9-tetrahydrocannabinol which, in its native form in the living cannabis plant, is non-psychoactive tetrahydrocannabinolic acid (THCA or 2-COOH-THC). Heating, vaporizing or drying THCA strips off (decarboxylates) the carboxyl radical (-COOH) leaving psychoactive THC. CBDA is cannabidiolic acid. As with THCA, stripped of its -COOH radical, it becomes CBD or cannabidiol.
H-COOH is the simplest carboxylic organic acid. Called formic acid, it has the odor of ants (genus formica). Formic acid is found in ant venom. CH3-COOH is acetic acid, the sour chemical in vinegar. It's thought that THCA and CBDA help protect the cannabis plant from microbial and insect predation.
Recent research has shown CBDA, which has anti-inflammatory properties greater than THCA, to have powerful healing properties including management of schizophrenia.
According to Dr. Mitch Earleywine, researchers at Harvard showed that CBDA makes breast cancer cells kill themselves and researchers in Japan found CBDA keeps breast cancer cells from spreading.
This is further evidence that Berkeley Bio's proprietary and carefully calibrated Whole Plant Plus technology, to coin a phrase, as formulated in Dharmanol™ is the correct scientific and medical methodology that will win the marketplace.
From Hoye essay:
"Along with the CBD and mixed cannabinoid carboxylates, the third component of Dharmanol™ is a steam-distilled extract of a variety of strains of cannabis. This preparation contains the terpenes and terpenoids found in marijuana, many of which have been shown to have substantial medicinal value in themselves, as well as potentiating the activity of some of the cannabinoids."
"Low-dose tablets contain 5mg. CBD, 5 mg. mixed cannabinoid carboxylates, and 5 mg. of steam-distilled terpenes and terpenoids. A daily supplement such as this will gently stimulate the endo-cannabinoid system, which regulates and enhances many of the body’s own health-promoting processes, such as the immune system. These are the systems that keep cancer and other opportunistic diseases in check in otherwise-healthy individuals."
More on Dharmanol™ in the Hoye essay on :
"CBD is an important part of Dharmanol™ a new natural medicine recently developed by Berkeley Bio. Along with CBD, Dharmanol™ contains a wide array of natural cannabinoids that have been extracted from hemp/cannabis and preserved in their non-psychoactive form utilizing a proprietary technology developed by Gold and Apel."
"...the carboxylates present in Dharmanol™ go a long way towards providing the same benefits without the extreme difficulty of maintaining live marijuana plants."
"Dharmanol™ has been designed to provide the widest spectrum of beneficial compounds of the cannabis plant, in their non-psychoactive form..."
" Dharmanol™ has been designed to provide the widest spectrum of beneficial compounds of the cannabis plant, in their non-psychoactive form, just as the aforementioned capsules provided the widest healing array possible, but included the psychoactive THC."
"Dharmanol™ has been designed to treat any of the myriad of conditions for which physicians are now recommending that patients try cannabinoid medicine. Modern research tells us that this includes treatments for a great number of different conditions."
"Two additional benefits are present with Dharmanol™ that are not to be found with standard Simpson therapy. The removal of the psychoactivity allows patients who cannot tolerate Simpson oil to treat their conditions with adequate amounts of cannabinoids, and the removal of the psychoactivity allows patients to tolerate much larger doses."
"The capacity to increase the dosage by removing the psychoactivity holds much promise. The “standard” Simpson dose is well under one one-thousandth of the dose of cannabinoids said to be capable of causing physical harm to the organism. The reason that one gram is the dose recommended by Simpson is that few people could possibly tolerate more than this."
"With the amazing anecdotal results surrounding Simpson oil, combined with the fact that many of cannabis’ mechanisms are dose-dependent, it stands to reason that increasing the daily dose of cannabinoids ten, or perhaps one hundred times, could provide a medicine that no cancer could possibly stand up against. Hopefully, clinical trials of Dharmanol™ will show whether this is so."
We know that THC is the psychocactive delta9-tetrahydrocannabinol which, in its native form in the living cannabis plant, is non-psychoactive tetrahydrocannabinolic acid (THCA or 2-COOH-THC). Heating, vaporizing or drying THCA strips off (decarboxylates) the carboxyl radical (-COOH) leaving psychoactive THC. CBDA is cannabidiolic acid. As with THCA, stripped of its -COOH radical, it becomes CBD or cannabidiol.
H-COOH is the simplest carboxylic organic acid. Called formic acid, it has the odor of ants (genus formica). Formic acid is found in ant venom. CH3-COOH is acetic acid, the sour chemical in vinegar. It's thought that THCA and CBDA help protect the cannabis plant from microbial and insect predation.
Recent research has shown CBDA, which has anti-inflammatory properties greater than THCA, to have powerful healing properties including management of schizophrenia.
According to Dr. Mitch Earleywine, researchers at Harvard showed that CBDA makes breast cancer cells kill themselves and researchers in Japan found CBDA keeps breast cancer cells from spreading.
This is further evidence that Berkeley Bio's proprietary and carefully calibrated Whole Plant Plus technology, to coin a phrase, as formulated in Dharmanol™ is the correct scientific and medical methodology that will win the marketplace.
From Hoye essay:
"Along with the CBD and mixed cannabinoid carboxylates, the third component of Dharmanol™ is a steam-distilled extract of a variety of strains of cannabis. This preparation contains the terpenes and terpenoids found in marijuana, many of which have been shown to have substantial medicinal value in themselves, as well as potentiating the activity of some of the cannabinoids."
"Low-dose tablets contain 5mg. CBD, 5 mg. mixed cannabinoid carboxylates, and 5 mg. of steam-distilled terpenes and terpenoids. A daily supplement such as this will gently stimulate the endo-cannabinoid system, which regulates and enhances many of the body’s own health-promoting processes, such as the immune system. These are the systems that keep cancer and other opportunistic diseases in check in otherwise-healthy individuals."
More on Dharmanol™ in the Hoye essay on :
"CBD is an important part of Dharmanol™ a new natural medicine recently developed by Berkeley Bio. Along with CBD, Dharmanol™ contains a wide array of natural cannabinoids that have been extracted from hemp/cannabis and preserved in their non-psychoactive form utilizing a proprietary technology developed by Gold and Apel."
"...the carboxylates present in Dharmanol™ go a long way towards providing the same benefits without the extreme difficulty of maintaining live marijuana plants."
"Dharmanol™ has been designed to provide the widest spectrum of beneficial compounds of the cannabis plant, in their non-psychoactive form..."
" Dharmanol™ has been designed to provide the widest spectrum of beneficial compounds of the cannabis plant, in their non-psychoactive form, just as the aforementioned capsules provided the widest healing array possible, but included the psychoactive THC."
"Dharmanol™ has been designed to treat any of the myriad of conditions for which physicians are now recommending that patients try cannabinoid medicine. Modern research tells us that this includes treatments for a great number of different conditions."
"Two additional benefits are present with Dharmanol™ that are not to be found with standard Simpson therapy. The removal of the psychoactivity allows patients who cannot tolerate Simpson oil to treat their conditions with adequate amounts of cannabinoids, and the removal of the psychoactivity allows patients to tolerate much larger doses."
"The capacity to increase the dosage by removing the psychoactivity holds much promise. The “standard” Simpson dose is well under one one-thousandth of the dose of cannabinoids said to be capable of causing physical harm to the organism. The reason that one gram is the dose recommended by Simpson is that few people could possibly tolerate more than this."
"With the amazing anecdotal results surrounding Simpson oil, combined with the fact that many of cannabis’ mechanisms are dose-dependent, it stands to reason that increasing the daily dose of cannabinoids ten, or perhaps one hundred times, could provide a medicine that no cancer could possibly stand up against. Hopefully, clinical trials of Dharmanol™ will show whether this is so."
