- MRX-6 is a Topical, Non-Steroidal Anti-Inflammatory Cream in Phase II Trials for Eczema
- Celsus to present MRX-6 at Windover's Therapeutic Area Partnerships meeting
NEW YORK and LONDON, Oct. 21, 2013 (GLOBE NEWSWIRE) -- Celsus Therapeutics (OTCQB:CLSXY), an emerging growth, development-stage biopharmaceutical company, announced that the Company's MRX-6 treatment for eczema has been selected as one of the "Top 10 Autoimmune/Anti-Inflammatory Disease Projects to Watch" by Windhover Information, of Elsevier Business Intelligence, a global leader in the field of healthcare industry information. Celsus management will present the project to a select group of pharmaceutical company executives at Windhover's Therapeutic Area Partnerships meeting in Boston, November 18-20.
MRX-6 is Celsus' most advanced clinical stage program developed from the Company's platform of first-in-class, synthetic, non-steroidal anti-inflammatory drugs. Topline results from the multi-center, Phase II double blind trial of MRX-6 in chronic hand eczema secondary to allergic contact dermatitis (ACD) demonstrated safety and tolerability, and clinically meaningful efficacy in this difficult to treat condition.
"It is an honor to be selected as a Top 10 Project to Watch by Elsevier," said Gur Roshwalb, Chief Executive Officer of Celsus Therapeutics. "This selection is confirmation of our recent progress as a company, and the potential for MRX-6 to treat an important unmet need for a safe and effective topical treatment in eczema. We expect to file an Investigational New Drug Application for MRX-6 in 2014, as well as run additional supportive trials in atopic dermatitis."
"Selected companies have been screened using a strict set of judging criteria for the Top 10 award and represent what our committees consider among the most attractive opportunities the industry has to offer," said David Cassak, Vice President, Content, Elsevier Business Intelligence. "Winners have met rigorous criteria, including: unmet medical need, market potential, diversity of indications, strong science, multi-level partnering opportunities (biotech and pharma), potential for new opportunities beyond initial indications and corporate stability. As the industry leader in strategic analysis and transaction tracking, our main goal is to give these companies exposure to potential investors, partners, and acquirers."
Windhover's Top Projects to Watch are hand-picked by a panel of independent experts who screen hundreds of compounds and weigh their potential as future products. Many presenting companies in previous years have gone on to establish major partnerships.
About MFAIDs (Multi-Functional, Anti-Inflammatory Drugs)
Celsus Therapeutics is developing a platform of first-in-class, synthetic, non-steroidal anti-inflammatory drugs. They are designed to inhibit extracellular secretory phospholipase A 2 (sPLA 2 ), a catalytic enzyme responsible for initiating the inflammatory cascade through the production of arachidonic acid from membrane-associated phospholipids, specifically at the cell surface. MFAIDs can inhibit all sPLA 2 isomers without disrupting cytoplasmic phospholipase A 2 (cPLA 2 ), a crucial homeostatic enzyme within cells. MFAIDS also enrich cell surface glycosaminoglycans, protecting cells from exposure to oxygen radicals and certain cytokines
About MRX-6 – Dermatitis
MRX-6 is an MFAID topical cream treatment under development for treating skin inflammatory disorders, specifically allergic contact dermatitis and atopic dermatitis, also known as eczema. ACD and atopic dermatitis usually caused by environment allergens.
About Celsus Therapeutics Plc.
Celsus Therapeutics is an emerging clinical stage company focused on the development of a new class of non-steroidal, synthetic anti-inflammatory drugs termed Multi-Functional Anti-Inflammatory Drugs or MFAIDs. Celsus's MFAIDs represent a new therapeutic platform for the treatment of a broad array of inflammatory diseases, such as allergies and autoimmune diseases. Presently, the Company has two lead drug candidates in its clinical pipeline, MRX-6, a topical cream for contact dermatitis and MRX-4, a nasal spray for treating allergic rhinitis (hay fever). Other potential treatments in preclinical development include OPX-1 for ocular inflammation, CFX-1 for cystic fibrosis, and MRX-5 for inflammatory bowel disease.
About Elsevier Business Intelligence
Elsevier Business Intelligence, a global leader in the field of healthcare industry information, provides business intelligence on regulatory, business and reimbursement issues that are vital to the healthcare industry. Through a range of products including publications, conferences, e-learning, databases and reports, Elsevier Business Intelligence places biopharma and medical device professionals, and those who focus on these industries, at the forefront of knowledge, by providing the perfect combination of news and information together with penetrating insight and analysis. http://www.elsevierbi.com/
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Investor Relations Contact The Trout Group Graham Morrell 646-378-2954
