Xylo's Transformation: New Leadership and Innovative Advances

Xylo's Major Transformation and Vision

Xylo Bio, formerly known as Psylo, has officially rebranded to signify a new chapter in its commitment to neurotherapeutics. This shift aligns with the company's growing focus on neuroscience and breakthrough therapies designed for mental health.

Innovative Drug Discovery with Neuroplastogens

At the core of Xylo's advancements is its unique computationally enhanced drug discovery platform. This cutting-edge technology allows Xylo to create highly targeted neuroplastogens. These novel small molecule therapies aim to rejuvenate brain function by encouraging the growth and restructuring of neural circuits, focusing on the root causes of neurological conditions rather than simply alleviating symptoms.

XYL-1001: A Leading Candidate

XYL-1001 stands out as Xylo’s flagship project, representing a significant leap in the treatment of neurological disorders. This innovative chemical entity is designed to effectively rewire neural circuits without inducing hallucinatory side effects, offering a promising solution for patients. Furthermore, Xylo has commenced scale-up manufacturing for XYL-1001, with plans for first-in-human clinical trials on the horizon, taking place approximately in mid-2026. This represents a key milestone in Xylo's mission to lead in neurotherapeutic advancements.

Leadership Advancements

The rebranding of Xylo coincides with a strategic enhancement of its management team, following a successful Series Seed funding round, predominantly led by Tenmile Venture. This funding has enabled Xylo to bring on board visionaries like Dr. Elaine Stead and Margarita Chavez, who are both influential figures in biotech investment. Their diverse expertise adds significant value to Xylo, helping to steer its ambitious plans for innovation in neurotherapeutics.

Dr. Elaine Stead expressed her excitement by stating, "Xylo Bio is positioned to provide critical solutions addressing the myriad unmet needs in psychiatric and neurological healthcare. I look forward to supporting the company as it advances ground-breaking treatments."

Margarita Chavez also shared her insights: "The potential of Xylo Bio’s innovative approach in computational drug design and neuroscience is truly remarkable. I am thrilled to be part of this dedicated team working to bring impactful therapies to life for patients."

Engagement at the JPM Healthcare Conference

Xylo’s team is actively engaging with potential partners and investors during the prestigious JPM Healthcare Conference, showcasing insights into their innovative approaches and future direction. This event serves as a platform for Xylo to connect with like-minded individuals and companies eager to contribute to the transformative journey in neurotherapeutics.

About Xylo Bio

Founded in 2021 and rebranded in 2025, Xylo Bio is dedicated to revolutionizing lives through targeted neurotherapeutics. The company employs advanced neuroscience to develop its neuroplastogens, sophisticated therapies tailored to restructure neural circuits and restore optimal brain function for patients with neurological disorders. This rebranding underscores Xylo's evolution and enhanced focus on bringing innovative solutions to the healthcare landscape.

Frequently Asked Questions

What led to the rebranding from Psylo to Xylo?

The rebranding to Xylo represents a strategic shift toward a more focused mission in developing neurotherapeutics and reflects the company's growth and commitment to innovation.

What is the significance of XYL-1001 in Xylo's pipeline?

XYL-1001 is Xylo's lead candidate drug aimed at addressing neurological disorders with a unique approach, promising effectiveness without the hallucinatory side effects common in other treatments.

Who are the new leadership appointments at Xylo?

Dr. Elaine Stead and Margarita Chavez have joined Xylo's board, bringing invaluable experience in biotech investment and innovation to enhance the company's strategic direction.

What are neuroplastogens?

Neuroplastogens are a novel class of small molecule therapies designed to promote the growth and restructuring of neural circuits, aimed at treating the root causes of neurological disorders.

How is Xylo engaging with the healthcare community?

Xylo is participating in the JPM Healthcare Conference to showcase its innovative therapies and connect with partners and investors who support its vision for transforming neurotherapeutics.

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