Turn Therapeutics Breakthrough: Live Vaccine Stability Achieved
Turn Therapeutics Achieves Remarkable Milestone
Turn Therapeutics has made a significant advancement by successfully maintaining the viability of a live vaccine for 24 hours at room temperature. This achievement comes through the innovative use of its oil suspension technology, which stabilizes a well-recognized vaccine vector in a viscous oil delivery solution. This breakthrough is crucial for enhancing the storage, transport, and administration of vaccines worldwide, particularly in areas facing challenges with refrigeration and deep-freeze storage.
Shattering Long-Standing Myths
As noted by Bradley Burnam, the CEO of Turn Therapeutics, this discovery challenges the traditional assumption that lipid carriers tend to destabilize or compromise lipid-enveloped vaccines. Previous claims suggested that achieving stability in such conditions was nearly impossible. However, evidence from multiple studies indicates that within their unique liquid-in-oil system, this notion is not entirely accurate. The findings suggest a new path for vaccine delivery, particularly as we consider the urgent needs of global health.
The Importance of Live Vaccines
Live vaccines play a crucial role in immunization, as they use a weakened form of the virus that they are designed to protect against. These vaccines often have stringent handling requirements, needing deep freezing during transportation and specific refrigeration at the point of use. Conventionally, once these vaccines are out of refrigeration, clinicians have only a brief window of three to five hours to administer them while they remain effective. These limitations pose significant barriers, particularly for remote regions where access to such cold chain capabilities is limited or non-existent.
Advancements in Delivery Systems
During their testing, Turn Therapeutics utilized a vaccine that is typically only stable for up to four hours at room temperature in its conventional liquid state. Through their lab's multi-step suspension technique, they not only preserved the vaccine’s viability but also ensured the vaccine remained effective when left uncovered at room temperature for a full 24 hours. This breakthrough is paving the way for improved delivery mechanisms that prioritize vaccine stability without compromising effectiveness.
Future Research Directions
Determined to explore the full range of this technology's capabilities, Turn Therapeutics is now studying the longer-term implications. The current focus is on advancing needle-free, intranasal vaccines that can endure transportation under less rigid conditions. As part of this exploration, researchers are examining whether the suspension method can extend the timeframe that vaccines remain viable at room temperature even further.
Revolutionizing Vaccine Access
After completing their ongoing studies, Turn Therapeutics plans to execute a comprehensive real-world simulation. This initiative aims to measure the stability of their vaccine delivery systems in both refrigerated and room-temperature scenarios. The end goal is to create a thermostable delivery mechanism that reduces the reliance on deep-freezing solutions, thereby extending the timeframe that vaccines remain viable under a variety of conditions. Success in this area could transform vaccine distribution for global health efforts, military operations, and rapid responses during outbreaks.
Bradley Burnam stated, "Currently, deep freeze storage requirements and brief stability periods contribute to making essential vaccines inaccessible in many remote areas. Turn Therapeutics envisions a future where the complexities of distribution won’t obstruct access to crucial therapeutics."
Contact and Company Information
For additional details or to schedule interviews, interested parties can reach out to Cooper Rumrill at (202) 980-4968. Turn Therapeutics specializes in developing pioneering solutions in the pharmaceutical and medical devices sector, particularly in advanced wound care and dermatological applications. The organization leverages proprietary technologies coupled with a patient-focused approach aimed at enhancing healthcare access and outcomes.
Frequently Asked Questions
What is the significance of Turn Therapeutics' breakthrough?
Turn Therapeutics has achieved a major milestone by maintaining vaccine viability at room temperature for 24 hours, enhancing access to vaccines globally.
How does this oil suspension technology work?
This technology stabilizes vaccine vectors in a viscous oil delivery system, making it easier to store and transport them without refrigeration.
What are the implications for live vaccines?
Live vaccines, typically requiring strict cold chain management, may become more accessible due to this new stability method.
What future studies are planned by Turn Therapeutics?
The company aims to conduct more research on extending vaccine viability and developing needle-free intranasal vaccines.
How can I learn more about Turn Therapeutics?
For more information, you can visit their official website or contact them directly through provided contact details.
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