TG Therapeutics Enhances 2025 Financial Outlook with BRIUMVI

Financial Performance Overview
TG Therapeutics, Inc. (NASDAQ: TGTX) recently provided an update on its financial results for the second quarter of 2025. The company proudly announced total revenues reaching $141.1 million, with BRIUMVI's U.S. net revenue contributing significantly at $138.8 million. This notable achievement underscores a remarkable growth trajectory, representing 91% increase from the previous year and an impressive 16% from the first quarter of 2025.
Updated Revenue Guidance
In light of its robust performance, TG Therapeutics has raised its full-year 2025 revenue expectations to approximately $570 - $575 million for BRIUMVI U.S. net revenue, reflecting the confidence the company has in its strategic approach to market penetration. The total global revenue target has also been raised to about $585 million, surpassing previous estimates.
Market Position and Product Highlights
Michael S. Weiss, the Chairman and CEO, expressed immense pride in the traction BRIUMVI has gained in the market. He emphasized that growing physician confidence in the product, along with positive patient experiences, reinforces the effectiveness of their launch strategy. BRIUMVI, a novel monoclonal antibody treating relapsing forms of multiple sclerosis (MS), continues to establish itself as a preferred option in this competitive space. The company is also focusing on significant innovations, including a subcutaneous formulation and streamlined dosing regimens.
Recent Developments
TG Therapeutics reported substantial progress in various aspects of commercialization:
- Expansion of BRIUMVI's market presence outside the U.S. in collaboration with Neuraxpharm, with approvals in the EU, UK, Switzerland, and Australia.
- Launching pivotal programs to study different dosing strategies within the ongoing ENHANCE trial.
- Advancing clinical trials for additional treatments targeting autoimmune diseases.
Financial Highlights from Q2 2025
For the three and six months ending June 30, 2025, TG Therapeutics reported the following key financial metrics:
- Net product revenue was $138.8 million compared to $72.6 million in the previous year.
- Total revenue for the same period was $141.1 million, compared to $73.5 million a year ago.
- Research and Development expenses increased to approximately $31.8 million, reflecting the company's commitment to further advancing BRIUMVI and related pipelines.
- Net income reached $28.2 million for the quarter, demonstrating a clear profitability progression.
Forward-Looking Strategy
As TG Therapeutics navigates through 2025, its strategies continue to evolve and expand. The company aims to enhance its ongoing pipeline development by:
- Initiating additional patient enrollment in the Phase 3 program for subcutaneous BRIUMVI.
- Continuing the enrollment in pivotal studies addressing various autoimmune disorders.
- Presenting findings at major medical conferences to further solidify its presence in the immunology field.
Investor Relations and Future Announcements
Investors and stakeholders are encouraged to stay updated by joining the ongoing discussions about TG Therapeutics' performance. A conference call was scheduled to delve deeper into these financial revelations and future prospects, hosted by TG Therapeutics' executive team.
Frequently Asked Questions
1. What is BRIUMVI used for?
BRIUMVI is used for treating adults with relapsing forms of multiple sclerosis (RMS), including relapsing-remitting MS.
2. How has TG Therapeutics performed in the recent quarters?
The company reported significant revenue growth, achieving $141.1 million in the second quarter of 2025, indicating strong market presence.
3. What revenue guidance has TG Therapeutics set for 2025?
The new revenue guidance for BRIUMVI is set between $570 - $575 million for the full year.
4. What innovations are being pursued by TG Therapeutics?
The company is enhancing its development of a subcutaneous formulation and exploring improved dosing regimens for BRIUMVI.
5. How can investors stay updated on TG Therapeutics?
Investors can stay informed through the company's website and by participating in scheduled conference calls with executive leadership.
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