Strategic Partnership to Advance Cancer Therapy Innovation

1ST Biotherapeutics and LigaChemBio Announce New Collaboration
The partnership between 1ST Biotherapeutics, Inc. and LigaChem Biosciences is a significant step towards revolutionizing cancer treatment. Both companies aim to bring their innovative research and development capabilities together to create trailblazing oncology therapeutics, which are expected to pave the way for improved patient outcomes.
Strengthening Oncology Therapeutics Development
In this strategic partnership, 1STBIO and LigaChemBio will pool their respective strengths to focus on the development of next-generation antibody-drug conjugate (ADC) payloads, as well as small molecule immuno-oncology therapies. These collaborative efforts underscore a commitment to addressing critical gaps in current oncology treatments.
Focused Innovation in ADC and Immuno-Oncology
The two organizations plan to identify and develop between two to four promising drug candidates over a three-year timeline. LigaChemBio will initiate funding to support the joint research and development (R&D) activities, and they will retain exclusive options to license the results of this collaboration. Once the options are exercised, LigaChemBio will have the opportunity to out-license the assets to third parties, sharing revenues with 1ST Biotherapeutics for any potential commercial success.
Expanding on an Existing Collaboration
This partnership builds upon a joint research project that commenced in late 2024. The teams recognized the complementary nature of their expertise and the significant potential for synergy, prompting LigaChemBio to extend the collaboration further. Together, they aspire not only to improve the existing ADC payloads but also to potentially develop first-in-class oncology treatment options.
Leadership Insights on the Collaboration
Jamie Jae Eun Kim, the CEO of 1ST Biotherapeutics, expressed confidence in their combined R&D capabilities, stating, “Our partnership aims to advance ADC payload innovation and significantly enhance small molecule immuno-oncology therapy. This alliance highlights our dedication to creating sustainable and innovation-driven relationships within the biotechnology sector.”
Likewise, Yong-Zu Kim, the CEO of LigaChemBio, conveyed enthusiasm for this collaboration, emphasizing the strength of 1ST Biotherapeutics in small molecule drug discovery and oncology. He also mentioned their ongoing commitment to pursue collaborations with biotech companies globally to develop transformative therapies that could benefit patients.
About 1ST Biotherapeutics, Inc.
Established in 2016, 1ST Biotherapeutics is a biopharmaceutical entity concentrating on cutting-edge therapies for immuno-oncology, neurodegenerative diseases, and rare diseases. The company has successfully built a pipeline of investigational drugs that aim to meet significant unmet medical needs. Based in South Korea, they are focused on advancing science through innovation, making strides in the biotech landscape to improve patient care.
About LigaChem Biosciences
LigaChem Biosciences, a clinical-stage biopharmaceutical firm founded in 2006, is renowned for its pioneering work in antibody-drug conjugates (ADCs) and anticancer therapies deriving from its proprietary ConjuAll™ platform technology. The company is devoted to developing groundbreaking therapeutics that leverage their medicinal drug discovery capabilities.
Frequently Asked Questions
What is the focus of the 1ST Biotherapeutics and LigaChemBio partnership?
The partnership primarily focuses on developing innovative antibody-drug conjugates and small molecule immuno-oncology therapies.
What is the timeframe for the development of new drug candidates?
1ST Biotherapeutics and LigaChemBio aim to develop 2–4 drug candidates over the next three years.
Will LigaChemBio have rights to commercialize the new therapies?
Yes, LigaChemBio will have licensing options to commercialize the new therapies once developed.
What types of diseases is 1ST Biotherapeutics targeting?
1ST Biotherapeutics targets immuno-oncology, neurodegenerative diseases, and rare diseases in its pipeline.
How does LigaChemBio innovate in drug development?
LigaChemBio utilizes its proprietary medicinal drug discovery technology and ADC platform technology to develop novel therapeutics.
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